RAB1A and GOLGA5

Number of citations of the paper that reports this interaction (PubMedID 12538640)
56

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		RAB1A	GOLGA5
Description		RAB1A, member RAS oncogene family	golgin A5
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endosome Early Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Endomembrane System Membrane Transport Vesicle Membrane Melanosome Extracellular Exosome	Golgi Membrane Golgi Apparatus Cis-Golgi Network Membrane Transport Vesicle Golgi Cisterna
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Cadherin Binding Metal Ion Binding	Small GTPase Binding Protein Homodimerization Activity
	Biological Process	Autophagosome Assembly Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endocytosis Autophagy Golgi Organization Protein Transport Vesicle-mediated Transport Cell Migration Virion Assembly Growth Hormone Secretion Melanosome Transport Positive Regulation Of Interleukin-8 Production Substrate Adhesion-dependent Cell Spreading Defense Response To Bacterium Vesicle Transport Along Microtubule Cilium Assembly COPII-coated Vesicle Cargo Loading Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process	Retrograde Transport, Vesicle Recycling Within Golgi Golgi Organization Golgi Vesicle Transport
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Intra-Golgi traffic
Drugs
Diseases
GWAS		High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Triglyceride levels ( 32154731)	Body mass index ( 26426971)
Interacting Genes		32 interacting genes: ADCK1 CAPNS1 CDKN1A CHML CREB1 CSNK1D FNDC3B FSCN1 GOLGA2 GOLGA5 GORASP2 HIVEP1 MAPRE3 MICAL1 MICALL1 MTOR OCRL PLK1 PSMD7 RABAC1 RABEP1 RABGGTA RABGGTB RFK RUSC2 SLC16A8 SNCA SSX2IP SYT5 TBC1D17 USO1 ZNF593	4 interacting genes: CUX1 ITSN1 OCRL RAB1A
Entrez ID		5861	9950
HPRD ID		01538	06079
Ensembl ID		ENSG00000138069	ENSG00000066455
Uniprot IDs		B7Z8M7 P62820 Q5U0I6	Q8TBA6
PDB IDs		2FOL 2WWX 3L0I 3SFV 3TKL 4FMB 4FMC 4FMD 4FME 4IRU 4JVS 7EQ2 9MHF 9MHG 9MHH
Enriched GO Terms of Interacting Partners?		Rab-protein Geranylgeranyltransferase Complex Protein Geranylgeranylation Small GTPase Binding Golgi Organization Protein Prenylation Vesicle-mediated Transport Organelle Organization Golgi Vesicle Transport Rab Geranylgeranyltransferase Activity Protein Geranylgeranyltransferase Activity Protein Prenyltransferase Activity Cytoplasm Organelle Assembly Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cellular Localization Protein Localization To Cytoskeleton Centrosome Cycle Cis-Golgi Network Establishment Of Localization In Cell Prenyltransferase Activity Protein Destabilization Cytoplasmic Vesicle Protein Localization To Cilium Spindle Organization Cytosol Ciliary Basal Body Cadherin Binding Intracellular Transport Behavioral Response To Cocaine Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Microtubule Organizing Center Organization Positive Regulation Of Protein-containing Complex Assembly Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Vesicle Fusion Establishment Of Protein Localization Cell Projection Assembly Spindle Assembly Protein Serine/threonine Kinase Binding Protein Localization To Organelle GTPase Activator Activity Chemotaxis To Arachidonate Regulation Of Protein-containing Complex Assembly Microtubule Nucleation Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Cilium Assembly Cellular Component Assembly Protein Localization To Centrosome Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Lamellipodium Assembly Regulation Of Organelle Assembly	Collagen Type XV Trimer Golgi Apparatus Clathrin-coated Pit Phosphatidylinositol Bisphosphate Phosphatase Activity Clathrin-dependent Synaptic Vesicle Endocytosis Cortical Microtubule Plus-end Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity Inositol Phosphate Phosphatase Activity Phosphatidylinositol-3,5-bisphosphate 5-phosphatase Activity Endosome Inositol-polyphosphate 5-phosphatase Activity Phosphatidylinositol Phosphate 5-phosphatase Activity Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Inositol-1,4,5-trisphosphate 5-phosphatase Activity Phosphatidylinositol Phosphate 4-phosphatase Activity Growth Hormone Secretion Positive Regulation Of Caveolin-mediated Endocytosis Regulation Of Caveolin-mediated Endocytosis Molecular Adaptor Activity Regulation Of Modification Of Postsynaptic Actin Cytoskeleton Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Cilium Assembly Endomembrane System Virion Assembly Postsynaptic Endocytic Zone Postsynaptic Actin Cytoskeleton Positive Regulation Of Growth Hormone Secretion Positive Regulation Of Microtubule Nucleation Golgi Vesicle Transport Astral Microtubule Organization
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