ZNF250 and CARD9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZNF250	CARD9
Gene Name		zinc finger protein 250	caspase recruitment domain family, member 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding	Protein Homodimerization Activity CARD Domain Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Response To Fungus Response To Peptidoglycan Response To Muramyl Dipeptide Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Stress-activated MAPK Cascade Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Drug Regulation Of Tumor Necrosis Factor Biosynthetic Process Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Exogenous DsRNA Regulation Of Interleukin-2 Biosynthetic Process Innate Immune Response Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of JNK Cascade Defense Response To Gram-positive Bacterium Defense Response To Virus Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Pathways		Generic Transcription Pathway	Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways NOD1/2 Signaling Pathway Innate Immune System
Drugs
Diseases
GWAS			Ankylosing spondylitis ( 21743469) Crohn's disease ( 22936669 21102463) Inflammatory bowel disease ( 23128233) Monocyte chemoattractant protein-1 ( 23017229) Obesity-related traits ( 23251661) Ulcerative colitis ( 19915572 20228799 21297633)
Protein-Protein Interactions		44 interactors: BEGAIN CARD9 CCDC102B CCDC136 CCDC155 CCDC85B CDCA7L CEP44 DPPA2 DVL2 FAM124A GMCL1 GNPTAB GOLGA2 HOOK1 HOOK2 KRT40 KRTAP10-3 KRTAP10-7 KRTAP4-12 LDOC1 LZTS2 MAGOHB MID2 MTUS2 NINL PLEKHF2 PRPF31 SSX2IP SYNE4 TFF1 TMCC2 TNNT1 TNS2 TRIM23 TRIM27 TRIM41 TRIM54 ZBTB8A ZC4H2 ZNF165 ZNF175 ZNF460 ZNF473	65 interactors: ABLIM1 AES ALS2CR11 AMOTL2 BCL10 BLZF1 C1orf94 CCDC36 CCDC85B CCHCR1 CDCA7L CEP57L1 CEP70 CSNK2A1 CWF19L2 DAXX DUSP13 EIF4E2 FAM124B FAM161A FAM208B FAM50B HMBOX1 IQCE KCTD9 KIAA0408 KIF9 KRT19 KRT31 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 LENG1 LMO1 LZTS2 MEOX2 MFAP1 NECAB2 PAK7 PBX2 PHC2 PNMA5 PPP1R18 RTP5 SSX2IP STX11 SUMO1 TCEANC TCL1A TFIP11 TNFAIP1 TRIM23 TRIM29 TRIM42 TRIM54 TSNAX USP15 VPS28 ZCCHC7 ZNF250 ZNF417 ZNF572 ZNF587 ZNF655
Entrez ID		58500	64170
HPRD ID		15758	06236
Ensembl ID		ENSG00000196150	ENSG00000187796
Uniprot IDs		B3KNS9 P15622	Q9H257
PDB IDs
Enriched GO Terms of Interacting Partners?		Lysosome Organization Negative Regulation Of Viral Release From Host Cell Early Endosome To Late Endosome Transport Vacuole Organization Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Transcription, DNA-templated Endosome To Lysosome Transport RNA Metabolic Process Endosome Organization RNA Biosynthetic Process Chromosome Localization To Nuclear Envelope Involved In Synapsis Gene Expression Lysosomal Transport	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Organelle Organization Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Developmental Process Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Wnt Signaling Pathway Spliceosomal Complex Disassembly Organelle Assembly Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Mast Cell Cytokine Production Histone H2B Conserved C-terminal Lysine Deubiquitination Lymphotoxin A Biosynthetic Process Interleukin-6 Biosynthetic Process Negative Regulation Of Biosynthetic Process
Tagcloud ?		automated calcein cloned fluorescence genomics initially integrated integrates jun lab luciferase modulating mtt opportunity plasmid prl profiling renilla reporter rnai screen sgol1 stain technologies throughput traf3 traf3ip3 znf306 znf434	adapter assembly danger defense discuss engaged framework fungal homeostasis inducible innate lectin links lymphoid lymphoma malt mucosa multifunctional nonredundant oligomerization paracaspase polymorphisms responds rig rlrs sensors spleen syk
Tagcloud (Difference) ?		automated calcein cloned fluorescence genomics initially integrated integrates jun lab luciferase modulating mtt opportunity plasmid prl profiling renilla reporter rnai screen sgol1 stain technologies throughput traf3 traf3ip3 znf306 znf434	adapter assembly danger defense discuss engaged framework fungal homeostasis inducible innate lectin links lymphoid lymphoma malt mucosa multifunctional nonredundant oligomerization paracaspase polymorphisms responds rig rlrs sensors spleen syk
Tagcloud (Intersection) ?