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BBS4 and EXOC7
Number of citations of the paper that reports this interaction (PubMedID
18000879
)
0
Data Source:
BioGRID
(two hybrid)
BBS4
EXOC7
Description
Bardet-Biedl syndrome 4
exocyst complex component 7
Image
No pdb structure
GO Annotations
Cellular Component
Pericentriolar Material
Photoreceptor Outer Segment
Photoreceptor Inner Segment
Nucleus
Cytoplasm
Centrosome
Centriole
Cytosol
Cytoskeleton
Plasma Membrane
Cilium
Membrane
Motile Cilium
Photoreceptor Connecting Cilium
Centriolar Satellite
BBSome
Ciliary Transition Zone
Ciliary Basal Body
Cell Projection
Ciliary Membrane
Non-motile Cilium
Exocyst
Cytoplasm
Microtubule Organizing Center
Cytosol
Plasma Membrane
Membrane
Midbody
Growth Cone Membrane
Centriolar Satellite
Flemming Body
Molecular Function
Protein Binding
Protein-macromolecule Adaptor Activity
Dynactin Binding
Alpha-tubulin Binding
Beta-tubulin Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Protein-macromolecule Adaptor Activity
Biological Process
Microtubule Cytoskeleton Organization
Mitotic Cytokinesis
Neuron Migration
Leukocyte Homeostasis
B Cell Homeostasis
Neural Tube Closure
Retina Homeostasis
Heart Looping
Lymphocyte Homeostasis
Myeloid Cell Homeostasis
Negative Regulation Of Systemic Arterial Blood Pressure
Centrosome Cycle
Spermatid Development
Sensory Perception
Visual Perception
Sensory Perception Of Smell
Intracellular Protein Localization
Gene Expression
Negative Regulation Of Gene Expression
Protein Transport
Wnt Signaling Pathway
Dendrite Development
Regulation Of Lipid Metabolic Process
Ventricular System Development
Striatum Development
Hippocampus Development
Cerebral Cortex Development
Cell Projection Organization
Adult Behavior
Negative Regulation Of Actin Filament Polymerization
Melanosome Transport
Regulation Of Cytokinesis
Leptin-mediated Signaling Pathway
Protein Localization To Organelle
Erythrocyte Homeostasis
Microtubule Anchoring At Centrosome
Social Behavior
Photoreceptor Cell Outer Segment Organization
Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway
Positive Regulation Of Multicellular Organism Growth
Response To Leptin
Fat Cell Differentiation
Photoreceptor Cell Maintenance
Positive Regulation Of Cilium Assembly
Retinal Rod Cell Development
Brain Morphogenesis
Homeostasis Of Number Of Cells
Sensory Processing
Maintenance Of Protein Location In Nucleus
Regulation Of Stress Fiber Assembly
Cilium Assembly
Regulation Of Cilium Beat Frequency Involved In Ciliary Motility
Face Development
Adipose Tissue Development
Fat Pad Development
Protein Localization To Cilium
Protein Localization To Centrosome
Sperm Flagellum Assembly
Regulation Of Non-motile Cilium Assembly
Protein Localization To Photoreceptor Outer Segment
Non-motile Cilium Assembly
Mitotic Cytokinesis
Exocytosis
Vesicle Docking Involved In Exocytosis
Protein Transport
Regulation Of Macroautophagy
Protein Transmembrane Transport
Membrane Fission
Vesicle Tethering Involved In Exocytosis
Positive Regulation Of Mitotic Cytokinetic Process
Regulation Of Entry Of Bacterium Into Host Cell
Pathways
BBSome-mediated cargo-targeting to cilium
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Insulin processing
VxPx cargo-targeting to cilium
Drugs
Diseases
Bardet-Biedl syndrome (BBS)
GWAS
Body mass index (
28448500
29273807
)
Body mass index (joint analysis main effects and physical activity interaction) (
28448500
)
Body mass index in physically active individuals (
28448500
)
Mild obesity-related type 2 diabetes (
34737425
)
Theory of mind score in adolescence (Emotional Triangles Task) (
29472613
)
Triglycerides (
30275531
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Body size at age 10 (
32376654
)
Interacting Genes
23 interacting genes:
ACTB
BHMT
CALCA
CATSPERT
DCTN1
EEF1A1
EIF3A
EPAS1
EXOC7
FHOD1
HSCB
KRT18
MYOG
OAS1
PAX2
PCM1
RARA
RARG
REL
SPIRE1
TOM1
TOM1L2
ZIC1
40 interacting genes:
AKTIP
ARFGEF2
ARPC1A
BBS1
BBS2
BBS4
CCDC85B
CCHCR1
CDC5L
CT55
DISC1
DLG3
EXOC2
EXOC4
FBXO28
GRIN2B
HGS
IFT20
KDM1A
KIFC3
KXD1
MSGN1
NRIP1
OLIG2
PKNOX1
PLEKHF2
PRPF19
RALA
RALY
RHOQ
RTN4IP1
SAPCD2
SMARCE1
SNAPIN
SSC5D
TRAF4
TRIM54
USHBP1
YAE1
ZC3H14
Entrez ID
585
23265
HPRD ID
08982
16292
Ensembl ID
ENSG00000140463
ENSG00000182473
Uniprot IDs
A0A0S2Z3A9
B4DQR5
Q96RK4
B4DJ07
B5MCY9
Q9UPT5
PDB IDs
6XT9
Enriched GO Terms of Interacting Partners
?
Nucleus Localization
Nuclear Migration
Trachea Cartilage Development
Glandular Epithelial Cell Development
Centriolar Satellite
DNA-binding Transcription Factor Activity
Microtubule Anchoring At Centrosome
Embryonic Organ Development
Growth Plate Cartilage Development
Positive Regulation Of Metabolic Process
Cytoplasm
Regulation Of Cell Development
Positive Regulation Of Macromolecule Biosynthetic Process
Cytosol
Response To Peptide
Vesicle-mediated Transport
Response To Cytokine
Microtubule Anchoring At Microtubule Organizing Center
Surfactant Homeostasis
Cis-regulatory Region Sequence-specific DNA Binding
Tube Closure
Camera-type Eye Development
Cellular Response To Retinoic Acid
Neural Tube Closure
Columnar/cuboidal Epithelial Cell Development
Embryonic Camera-type Eye Development
Nucleoplasm
Cartilage Development Involved In Endochondral Bone Morphogenesis
Positive Regulation Of Biosynthetic Process
Microtubule Organizing Center
Positive Regulation Of Cell Development
Positive Regulation Of Macromolecule Metabolic Process
Transcription Regulator Complex
Positive Regulation Of Transcription By RNA Polymerase II
Response To Retinoic Acid
Retinoic Acid Receptor Signaling Pathway
Face Development
Microtubule Anchoring
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Organelle Localization
Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Establishment Of Organelle Localization
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Eye Development
Protein-containing Complex
Tube Formation
Negative Regulation Of Cartilage Development
Chromatin
BBSome
Golgi To Plasma Membrane Transport
Vesicle-mediated Transport To The Plasma Membrane
Regulation Of Cilium Beat Frequency Involved In Ciliary Motility
Vesicle-mediated Transport
Localization Within Membrane
Cytoskeleton
Intracellular Protein Localization
Cellular Localization
Protein Transport
Establishment Of Protein Localization
Post-Golgi Vesicle-mediated Transport
Striatum Development
Regulation Of Cilium Beat Frequency
Non-motile Cilium Assembly
Microtubule-based Process
Brain Morphogenesis
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Regulation Of Cell Projection Organization
Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway
Endosome Organization
Cerebral Cortex Development
Flemming Body
Protein Binding
Regulation Of Cilium Movement
Organelle Localization
Exocytosis
Centrosome
Photoreceptor Cell Maintenance
Motile Cilium
Regulation Of Lysosome Size
BORC Complex
Membrane Fission
Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly
Positive Regulation Of Cell Projection Organization
Cytoplasm
Vesicle Tethering Involved In Exocytosis
Lysosomal Transport
Leptin-mediated Signaling Pathway
Regulation Of Microtubule-based Movement
Ciliary Membrane
Regulation Of Endosome Size
Endosome To Lysosome Transport
Cilium Assembly
Negative Regulation Of Appetite
Establishment Of Organelle Localization
Protein Localization To Cilium
DNA Replication Factor A Complex
Cytoplasmic Side Of Lysosomal Membrane
Golgi Vesicle Transport
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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