SNTB2 and SCN4A

Number of citations of the paper that reports this interaction (PMID 9412493)
66

Data Source:
HPRD (in vivo)

		SNTB2	SCN4A
Gene Name		syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	sodium channel, voltage gated, type IV alpha subunit
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule Focal Adhesion Dystrophin-associated Glycoprotein Complex Membrane Transport Vesicle Membrane Protein Complex Synapse Extracellular Vesicular Exosome	Voltage-gated Sodium Channel Complex Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Actin Binding Protein Binding Calmodulin Binding Poly(A) RNA Binding	Voltage-gated Sodium Channel Activity
	Biological Process		Sodium Ion Transport Muscle Contraction Neuronal Action Potential Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Membrane Depolarization During Action Potential
Pathways			Interaction between L1 and Ankyrins Axon guidance L1CAM interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: ABCA1 ADRA1D BAI1 DGKZ DMD DTNA ERBB4 KCNJ12 MAST1 MAST2 PTPRN SCN4A SCN5A UBC UTRN	10 interactors: CALM1 DLG1 DLG2 DLG3 ERBB2IP INADL SLC9A3R1 SNTA1 SNTB1 SNTB2
Entrez ID		6645	6329
HPRD ID		02491	04912
Ensembl ID		ENSG00000168807	ENSG00000007314
Uniprot IDs		Q13425	P35499
PDB IDs		2VRF
Enriched GO Terms of Interacting Partners?		Muscle Contraction Muscle System Process Signaling Cell Communication Regulation Of Sodium Ion Transmembrane Transport Regulation Of Heart Contraction Regulation Of Ion Transmembrane Transport Regulation Of Sodium Ion Transport Cell-cell Signaling Action Potential Striated Muscle Contraction Regulation Of Ion Transport Regulation Of Cellular Process Regulation Of Sodium Ion Transmembrane Transporter Activity Neuronal Action Potential Cardiac Muscle Cell Action Potential Membrane Depolarization During Action Potential Positive Regulation Of Sodium Ion Transport Signal Transduction Cellular Response To Stimulus Cardiac Muscle Contraction Positive Regulation Of Cell-matrix Adhesion Regulation Of Membrane Potential Transmission Of Nerve Impulse Cardiac Muscle Tissue Regeneration Negative Regulation Of The Force Of Heart Contraction Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Heart Contraction Peptide Secretion Blood Circulation Positive Regulation Of Transport Ion Transmembrane Transport Mitotic G1 DNA Damage Checkpoint Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Regulation Of Striated Muscle Contraction Central Nervous System Morphogenesis Establishment Of Glial Blood-brain Barrier Dense Core Granule Maturation Cell Projection Morphogenesis Cell Surface Receptor Signaling Pathway Peptide Transport Movement Of Cell Or Subcellular Component Mitotic DNA Damage Checkpoint Cell Part Morphogenesis Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Positive Regulation Of STAT Protein Import Into Nucleus Negative Regulation Of Peptidyl-cysteine S-nitrosylation	Receptor Localization To Synapse Protein Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Regulation Of Sodium Ion Transmembrane Transport Muscle Contraction Receptor Clustering Nucleotide Phosphorylation Muscle System Process Regulation Of Sodium Ion Transport Regulation Of Phosphatase Activity Regulation Of Ion Transmembrane Transport Regulation Of Dephosphorylation Establishment Or Maintenance Of Cell Polarity Synaptic Transmission Regulation Of Ion Transport Cellular Protein Localization Cellular Localization Negative Regulation Of Protein Kinase B Signaling Regulation Of Phosphorus Metabolic Process Negative Regulation Of Transporter Activity Negative Regulation Of Ion Transmembrane Transport Tight Junction Assembly Membrane Organization Negative Regulation Of Transmembrane Transport Negative Regulation Of Phosphatase Activity Cell-cell Signaling Protein Localization To Membrane Negative Regulation Of Dephosphorylation Protein Localization Apical Junction Assembly Regulation Of Heart Rate Organophosphate Metabolic Process Regulation Of Cardiac Muscle Contraction Regulation Of Vasoconstriction By Circulating Norepinephrine Renal Phosphate Ion Absorption Regulation Of Striated Muscle Contraction Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Ion Transport Negative Regulation Of Sodium:proton Antiporter Activity Basal Protein Localization Glutathione Transport Cell-cell Junction Assembly Regulation Of Catalytic Activity Regulation Of Protein Kinase B Signaling Signaling Nucleotide Metabolic Process Cell Communication Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity
Tagcloud ?		adp cleaved clonogenic concomitantly degs discovering ebp elucidating exhibiting fractionated grp78 h1299 h2ax h460 h460r helpful ionizing ir metalloproteinase organelles overcome parental radioresistance radioresistant ribose scattering syntrophin vesicular zymography	blotting chorionic cloned cs deoxyribonuclease evolutionarily genomes gh homologue hypersensitive immediately implies insert kb kilobases linkage loci locus orientation p1 physically pig pituitary somatomammotropin sug transcriptase trip ubiquitously unlike
Tagcloud (Difference) ?		adp cleaved clonogenic concomitantly degs discovering ebp elucidating exhibiting fractionated grp78 h1299 h2ax h460 h460r helpful ionizing ir metalloproteinase organelles overcome parental radioresistance radioresistant ribose scattering syntrophin vesicular zymography	blotting chorionic cloned cs deoxyribonuclease evolutionarily genomes gh homologue hypersensitive immediately implies insert kb kilobases linkage loci locus orientation p1 physically pig pituitary somatomammotropin sug transcriptase trip ubiquitously unlike
Tagcloud (Intersection) ?