SNTB2 and MAST1

Number of citations of the paper that reports this interaction (PubMedID 10404183)
0

Data Source:
HPRD (in vivo, two hybrid)

		SNTB2	MAST1
Description		syntrophin beta 2	microtubule associated serine/threonine kinase 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Microtubule Plasma Membrane Focal Adhesion Dystrophin-associated Glycoprotein Complex Membrane Transport Vesicle Membrane Cytoplasmic Vesicle Protein-containing Complex Centriolar Satellite Ciliary Basal Body Synapse Anchoring Junction	Cytoplasm Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Membrane Axon Dendrite Cell Projection Neuron Projection Neuronal Cell Body
	Molecular Function	RNA Binding Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process		Protein Phosphorylation Cytoskeleton Organization Brain Development Developmental Process Intracellular Signal Transduction
Pathways		Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs			Fostamatinib
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287) Logical memory (delayed recall) in normal cognition ( 29274321)	High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 32888494) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252 32888494) Red blood cell count ( 29403010) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		16 interacting genes: ABCA1 ADGRB1 ADRA1D DGKZ DMD DTNA ERBB4 KCNJ12 MAST1 MAST2 PTEN PTPRN SCN4A SCN5A UBC UTRN	41 interacting genes: A2M ACE2 AP1M2 APOE APP BLMH CDK5 CYP2C8 CYP2C9 DNAJB1 ECSIT EGFR ELAVL3 EXOC6 EXOSC1 FBXL12 FBXW4 GCDH IFIT3 IFIT5 LONP1 LOXL4 NOS3 OGA PAXIP1 PRAM1 PRDX2 PSEN2 PTEN RAB3A RAB3D RAD23A RNF32 RNLS RPP30 RPS6KA1 SNTA1 SNTB2 STAMBPL1 TIAM1 VANGL2
Entrez ID		6645	22983
HPRD ID		02491	17469
Ensembl ID		ENSG00000168807	ENSG00000105613
Uniprot IDs		Q13425	Q9Y2H9
PDB IDs		2VRF	2M9X 3PS4
Enriched GO Terms of Interacting Partners?		Plasma Membrane Muscle Contraction Muscle System Process Sarcolemma Regulation Of System Process Regulation Of Sodium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential Membrane Cell Communication System Process Regulation Of Sodium Ion Transport PDZ Domain Binding Vinculin Binding Striated Muscle Contraction Nitric-oxide Synthase Binding Voltage-gated Sodium Channel Complex Regulation Of Multicellular Organismal Process Regulation Of Blood Circulation Dystrophin-associated Glycoprotein Complex Regulation Of Striated Muscle Contraction Voltage-gated Sodium Channel Activity Synapse Regulation Of Monoatomic Ion Transmembrane Transport Filopodium Membrane Action Potential Regulation Of Skeletal Muscle Contraction Regulation Of Biological Quality Cell-cell Signaling Muscle Organ Development Monoatomic Ion Channel Complex Signaling Synaptic Signaling Muscle Structure Development Regulation Of Transport Phagocytosis, Engulfment Phosphorylation Monoatomic Cation Channel Activity Regulation Of Monoatomic Ion Transport Sodium Channel Activity Regulation Of Muscle Contraction Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Membrane Potential Cell Projection Cardiac Muscle Contraction Membrane Invagination Sphingolipid Floppase Activity Regulation Of Heart Contraction Positive Regulation Of Epithelial Cell Proliferation Establishment Of Planar Polarity Involved In Nephron Morphogenesis T-tubule	Lipoprotein Particle Acetylcholine Receptor Activator Activity Negative Regulation Of Smooth Muscle Cell Proliferation Caffeine Oxidase Activity Intermediate-density Lipoprotein Particle Positive Regulation Of Amyloid Fibril Formation Chemical Synaptic Transmission Catabolic Process Cytosol Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Trans-synaptic Signaling Oxidative Demethylation Synaptic Signaling Cellular Response To Amyloid-beta Positive Regulation Of Regulated Secretory Pathway Regulation Of Regulated Secretory Pathway Omega-hydroxylase P450 Pathway Oxidoreductase Activity Arachidonate Epoxygenase Activity Regulation Of Neuronal Synaptic Plasticity Regulation Of Wound Healing Negative Regulation Of Long-term Synaptic Potentiation Regulation Of System Process Regulation Of Blood Circulation Demethylation Regulation Of Dendritic Spine Maintenance Response To Amyloid-beta Regulation Of Smooth Muscle Cell Proliferation Learning Or Memory Axonogenesis Epoxygenase P450 Pathway Low-density Lipoprotein Particle Removal Of Superoxide Radicals Negative Regulation Of Wound Healing Regulation Of Blood Coagulation Positive Regulation Of Membrane Protein Ectodomain Proteolysis Myosin V Binding Dystrophin-associated Glycoprotein Complex Regulation Of Hemostasis Heparan Sulfate Proteoglycan Binding Intracellular Signaling Cassette Regulation Of Amyloid Fibril Formation Regulation Of Response To Wounding Negative Regulation Of Platelet Activation Cognition Cellular Oxidant Detoxification Regulation Of Transport Ubiquitin-specific Protease Binding Very-low-density Lipoprotein Particle Regulation Of Amyloid-beta Clearance
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