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PTPRG and PPFIA3
Number of citations of the paper that reports this interaction (PMID
9624153
)
49
Data Source:
BioGRID
(two hybrid)
PTPRG
PPFIA3
Gene Name
protein tyrosine phosphatase, receptor type, G
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Integral Component Of Plasma Membrane
Extracellular Vesicular Exosome
Cytosol
Cell Surface
Presynaptic Active Zone
Molecular Function
Protein Tyrosine Phosphatase Activity
Transmembrane Receptor Protein Tyrosine Phosphatase Activity
Protein Binding
Identical Protein Binding
Protein Binding
Biological Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Brain Development
Negative Regulation Of Epithelial Cell Migration
Negative Regulation Of Neuron Projection Development
Peptidyl-tyrosine Dephosphorylation
Toxin Transport
Regulation Of Homophilic Cell Adhesion
Synaptic Transmission
Neurotransmitter Secretion
Glutamate Secretion
Regulation Of Short-term Neuronal Synaptic Plasticity
Pathways
Dopamine Neurotransmitter Release Cycle
Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Serotonin Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Breast size (
22747683
)
Fuchs's corneal dystrophy (
20825314
)
Major depressive disorder (
20125088
)
Metabolite levels (HVA/5-HIAA ratio) (
23319000
)
QT interval (
20031603
)
Protein-Protein Interactions
4 interactors:
DLG4
PPFIA1
PPFIA2
PPFIA3
12 interactors:
CAST
ERC2
GIT1
PPFIA1
PPFIA2
PPFIBP1
PPFIBP2
PTPRD
PTPRF
PTPRG
PTPRS
PTPRU
Entrez ID
5793
8541
HPRD ID
01478
04393
Ensembl ID
ENSG00000177380
Uniprot IDs
P23470
Q49A02
O75145
PDB IDs
2H4V
2HY3
2NLK
2PBN
3JXH
3QCB
3QCC
3QCD
3QCE
3QCF
3QCG
3QCH
3QCI
3QCJ
3QCK
3QCL
3QCM
3QCN
Enriched GO Terms of Interacting Partners
?
Glutamate Secretion
Acid Secretion
Dicarboxylic Acid Transport
Secretion By Cell
Neurotransmitter Secretion
Synaptic Transmission
Secretion
Regulation Of Neurotransmitter Levels
Amino Acid Transport
Neurotransmitter Transport
Cell-cell Signaling
Carboxylic Acid Transport
Organic Acid Transport
Organic Anion Transport
Regulation Of Neuronal Synaptic Plasticity
Establishment Of Localization In Cell
Anion Transport
Cellular Localization
Regulation Of Synaptic Plasticity
Cell-matrix Adhesion
Cell-substrate Adhesion
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering
Regulation Of Grooming Behavior
Regulation Of Synaptic Transmission
Maintenance Of Apical/basal Cell Polarity
Receptor Localization To Synapse
Negative Regulation Of Receptor Internalization
Negative Regulation Of Stress Fiber Assembly
Ion Transport
Locomotory Exploration Behavior
Dendritic Spine Morphogenesis
Maintenance Of Cell Polarity
Synaptic Vesicle Maturation
Negative Regulation Of Actin Filament Bundle Assembly
Transport
Regulation Of Short-term Neuronal Synaptic Plasticity
Vocalization Behavior
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Dendritic Spine Development
Protein Localization To Synapse
Negative Regulation Of Receptor-mediated Endocytosis
Signaling
Dendritic Spine Organization
Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity
Negative Regulation Of Protein Localization To Plasma Membrane
Cell Communication
Cortical Actin Cytoskeleton Organization
Exploration Behavior
Postsynaptic Membrane Organization
Establishment Or Maintenance Of Apical/basal Cell Polarity
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Peptidyl-tyrosine Dephosphorylation
Protein Dephosphorylation
Cell Adhesion
Enzyme Linked Receptor Protein Signaling Pathway
Dephosphorylation
Signaling
Cell Communication
Glutamate Secretion
Signal Transduction
Acid Secretion
Dicarboxylic Acid Transport
Cell Surface Receptor Signaling Pathway
Cellular Response To Stimulus
Neurotransmitter Secretion
Regulation Of Neurotransmitter Levels
Amino Acid Transport
Neurotransmitter Transport
Cell-matrix Adhesion
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Negative Regulation Of Cell Migration
Negative Regulation Of Receptor Binding
Cell-substrate Adhesion
Presynaptic Membrane Assembly
Negative Regulation Of Cell Motility
Phosphate-containing Compound Metabolic Process
Negative Regulation Of Stress Fiber Assembly
Negative Regulation Of Cellular Component Movement
Response To Stimulus
Presynaptic Membrane Organization
Negative Regulation Of Locomotion
Negative Regulation Of Actin Filament Bundle Assembly
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Cellular Protein Modification Process
Corpus Callosum Development
Carboxylic Acid Transport
Organic Acid Transport
Protein Localization To Cell Surface
Negative Regulation Of Protein Localization To Plasma Membrane
Membrane Assembly
RRNA Transcription
Regulation Of Neuron Projection Development
Nervous System Development
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Membrane Biogenesis
Tagcloud
?
australian
australians
borderline
caucasian
caucasians
clu
col8a2
corneal
corneas
dystrophy
endothelium
fed
finger
fuchs
genotyped
haplotype
homoebox
polymorphisms
rs17466684
rs17595731
rs2286812
rs613872
rs9954153
snp
snps
tcf4
tgfbi
viii
zeb1
Tagcloud (Difference)
?
australian
australians
borderline
caucasian
caucasians
clu
col8a2
corneal
corneas
dystrophy
endothelium
fed
finger
fuchs
genotyped
haplotype
homoebox
polymorphisms
rs17466684
rs17595731
rs2286812
rs613872
rs9954153
snp
snps
tcf4
tgfbi
viii
zeb1
Tagcloud (Intersection)
?