PTPRG and PPFIA1

Number of citations of the paper that reports this interaction (PMID 9624153)
49

Data Source:
BioGRID (two hybrid)

		PTPRG	PPFIA1
Gene Name		protein tyrosine phosphatase, receptor type, G	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Integral Component Of Plasma Membrane Extracellular Vesicular Exosome	Cytoplasm Cytosol Focal Adhesion Presynaptic Active Zone
	Molecular Function	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Identical Protein Binding	Signal Transducer Activity Protein Binding
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Brain Development Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Neuron Projection Development Peptidyl-tyrosine Dephosphorylation Toxin Transport Regulation Of Homophilic Cell Adhesion	Cell-matrix Adhesion Signal Transduction Synaptic Transmission Neurotransmitter Secretion Glutamate Secretion Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Pathways			Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Breast size ( 22747683) Fuchs's corneal dystrophy ( 20825314) Major depressive disorder ( 20125088) Metabolite levels (HVA/5-HIAA ratio) ( 23319000) QT interval ( 20031603)
Protein-Protein Interactions		4 interactors: DLG4 PPFIA1 PPFIA2 PPFIA3	25 interactors: AGTPBP1 CAST CCNH CEP70 DTNB ERC1 ERC2 FAM161A GIT1 MBIP NCOA2 NDN PPFIA2 PPFIA3 PPFIBP1 PPFIBP2 PPP2R5D PTPRC PTPRD PTPRF PTPRG PTPRS TNNT1 TXLNA YWHAG
Entrez ID		5793	8500
HPRD ID		01478	11451
Ensembl ID			ENSG00000131626
Uniprot IDs		P23470 Q49A02	B3KVS8 Q13136
PDB IDs		2H4V 2HY3 2NLK 2PBN 3JXH 3QCB 3QCC 3QCD 3QCE 3QCF 3QCG 3QCH 3QCI 3QCJ 3QCK 3QCL 3QCM 3QCN
Enriched GO Terms of Interacting Partners?		Glutamate Secretion Acid Secretion Dicarboxylic Acid Transport Secretion By Cell Neurotransmitter Secretion Synaptic Transmission Secretion Regulation Of Neurotransmitter Levels Amino Acid Transport Neurotransmitter Transport Cell-cell Signaling Carboxylic Acid Transport Organic Acid Transport Organic Anion Transport Regulation Of Neuronal Synaptic Plasticity Establishment Of Localization In Cell Anion Transport Cellular Localization Regulation Of Synaptic Plasticity Cell-matrix Adhesion Cell-substrate Adhesion Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Regulation Of Synaptic Transmission Maintenance Of Apical/basal Cell Polarity Receptor Localization To Synapse Negative Regulation Of Receptor Internalization Negative Regulation Of Stress Fiber Assembly Ion Transport Locomotory Exploration Behavior Dendritic Spine Morphogenesis Maintenance Of Cell Polarity Synaptic Vesicle Maturation Negative Regulation Of Actin Filament Bundle Assembly Transport Regulation Of Short-term Neuronal Synaptic Plasticity Vocalization Behavior Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Dendritic Spine Development Protein Localization To Synapse Negative Regulation Of Receptor-mediated Endocytosis Signaling Dendritic Spine Organization Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Negative Regulation Of Protein Localization To Plasma Membrane Cell Communication Cortical Actin Cytoskeleton Organization Exploration Behavior Postsynaptic Membrane Organization Establishment Or Maintenance Of Apical/basal Cell Polarity	Peptidyl-tyrosine Dephosphorylation Protein Dephosphorylation Dephosphorylation Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Signaling Cell Communication Cell Cycle Phase Transition Nervous System Development G2/M Transition Of Mitotic Cell Cycle Glutamate Secretion Cellular Protein Modification Process Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Transcription Initiation From RNA Polymerase I Promoter Generation Of Neurons Transcription From RNA Polymerase I Promoter Neurogenesis Cell Adhesion Signal Transduction Negative Regulation Of Protein Kinase Activity Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Negative Regulation Of Kinase Activity Acid Secretion Mitotic Cell Cycle Phase Transition Cellular Response To Stimulus Immunoglobulin Biosynthetic Process Positive Regulation Of Hematopoietic Stem Cell Migration DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transferase Activity Phosphate-containing Compound Metabolic Process Dicarboxylic Acid Transport DNA-templated Transcription, Elongation Cellular Protein Metabolic Process Negative Regulation Of Protein Phosphorylation Neuron Differentiation C-terminal Protein Deglutamylation Regulation Of Catalytic Activity Regulation Of Protein Kinase Activity Response To Stimulus Neurotransmitter Secretion Cell Surface Receptor Signaling Pathway Developmental Process Histone Acetylation Negative Regulation Of Catalytic Activity Cerebellum Development Regulation Of Kinase Activity Negative Regulation Of Phosphorylation
Tagcloud ?		australian australians borderline caucasian caucasians clu col8a2 corneal corneas dystrophy endothelium fed finger fuchs genotyped haplotype homoebox polymorphisms rs17466684 rs17595731 rs2286812 rs613872 rs9954153 snp snps tcf4 tgfbi viii zeb1	11q13 aberrations acgh aiming amplicon apart band breakpoints candidates ccnd1 chosen chr comprised copies cttn distinguish fadd gain homogeneously laryngeal microarray oncogene oncogenes oraov1 q13 rearrangements reinvestigated sevenfold ways
Tagcloud (Difference) ?		australian australians borderline caucasian caucasians clu col8a2 corneal corneas dystrophy endothelium fed finger fuchs genotyped haplotype homoebox polymorphisms rs17466684 rs17595731 rs2286812 rs613872 rs9954153 snp snps tcf4 tgfbi viii zeb1	11q13 aberrations acgh aiming amplicon apart band breakpoints candidates ccnd1 chosen chr comprised copies cttn distinguish fadd gain homogeneously laryngeal microarray oncogene oncogenes oraov1 q13 rearrangements reinvestigated sevenfold ways
Tagcloud (Intersection) ?