PTPRG

Description		protein tyrosine phosphatase receptor type G
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity Identical Protein Binding
	Biological Process	Signal Transduction Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Neuron Projection Development Neuron Projection Development Regulation Of Homophilic Cell Adhesion
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Alzheimer disease and age of onset ( 26830138) Bacteremia ( 27236921) Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Breast size ( 22747683) Daytime sleep phenotypes ( 27126917) Evening vs. morning chronotype (sMEQ score) ( 32579418) Femur bone mineral density x serum urate levels interaction ( 34046847) Fuchs's corneal dystrophy ( 20825314) Ischemic stroke ( 26089329) Major depressive disorder ( 29317602 20125088) Metabolite levels ( 23823483) Metabolite levels (HVA/5-HIAA ratio) ( 23319000) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600) QT interval ( 20031603) Smoking initiation (ever regular vs never regular) ( 30679032) Spontaneous preterm birth without premature rupture of membranes ( 31194736) Stroke ( 26089329) Waist circumference adjusted for body mass index ( 34021172)
Novel Interacting Genes		1 novel interacting genes: WNT5A
Interacting Genes		3 interacting genes: DLG4 PKD1 PKD2
Entrez ID		5793
HPRD ID		01478
Ensembl ID		ENSG00000144724
Uniprot IDs		P23470 Q49A02
PDB IDs		2H4V 2HY3 2NLK 2PBN 3JXH 3QCB 3QCC 3QCD 3QCE 3QCF 3QCG 3QCH 3QCI 3QCJ 3QCK 3QCL 3QCM 3QCN 5E5R 8XQD
Enriched GO Terms of Interacting Partners?		Polycystin Complex Neural Tube Development Migrasome Metanephric Ascending Thin Limb Development Nephric Duct Development Mesonephric Duct Development Positive Regulation Of Neuron Projection Arborization Epithelial Tube Morphogenesis Branching Morphogenesis Of An Epithelial Tube Regulation Of Neuron Projection Arborization Cellular Response To Metal Ion Establishment Or Maintenance Of Cell Polarity Kidney Development Metanephric Epithelium Development Morphogenesis Of A Branching Structure Morphogenesis Of A Branching Epithelium Protein Heterotetramerization Metanephric Tubule Development Metanephric Nephron Tubule Development Cation Channel Complex Renal Tubule Morphogenesis Tube Development Nephron Tubule Development Epithelium Development Embryonic Placenta Development Renal Tubule Development Protein Heterooligomerization Wnt Signaling Pathway Spinal Cord Development Placenta Blood Vessel Development Tube Morphogenesis Monoatomic Cation Channel Activity Response To Metal Ion Morphogenesis Of An Epithelium Genitalia Development Transcription Regulator Inhibitor Activity Response To Fluid Shear Stress Postsynapse Organization Detection Of Mechanical Stimulus Mesonephric Tubule Development Mesonephric Epithelium Development Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Anatomical Structure Morphogenesis Tissue Morphogenesis Establishment Or Maintenance Of Apical/basal Cell Polarity Digestive Tract Development Ciliary Membrane Heart Looping Cell Surface Receptor Signaling Pathway Via JAK-STAT Embryonic Heart Tube Morphogenesis
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