PRKCA and HSP90AA1

  • Number of citations of the paper that reports this interaction (PMID 22939624)
  • 59
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

PRKCA

HSP90AA1

Gene Name protein kinase C, alpha heat shock protein 90kDa alpha (cytosolic), class A member 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Height ( 22021425)
  • Post-traumatic stress disorder (asjusted for relatedness) ( 23726511)
  • Ventricular conduction ( 21076409)
Protein-Protein Interactions 210 interactors: ACTA1 ADAP1 ADCY5 ADD3 ADRA1B ADRBK1 AFAP1 AKAP12 AKAP5 ANXA2 ANXA7 APLP2 ARHGEF1 ATP1A1 ATP2B1 ATP2B2 AVPR1A BCL2 BTG2 BTK C1QBP CASR CBL CD163 CD5 CD9 CDC42 CDKN2A CFTR CHAT CISH CORO1B CREM CYP3A4 CYTH2 DDX5 DGKD DGKZ DLG4 DLX3 DNM1 DVL2 EDF1 EEF1D EGFR EIF4E EIF4EBP1 ELAVL1 ENTPD5 EP300 EWSR1 EZR F11R FAS FBXO25 FLNA FLNC FSCN1 GABRB3 GABRG2 GABRR1 GABRR2 GFAP GFPT1 GJA1 GJB1 GLI3 GMFB GNA12 GNA15 GNB2L1 GPM6A GRIA1 GRIA2 GRIA4 GRIN1 GRIN2A GRIN2B GRM1 GRM5 GSK3A GSK3B HABP4 HAND1 HAND2 HES1 HIST1H1A HIST1H1B HIST1H1C HIST1H1D HIST1H1E HIST1H1T HIST1H3A HIST3H3 HLA-A HMGA1 HMGA2 HMGB1 HMGN1 HMGN2 HSP90AA1 HSPA1A HSPB8 IKBKB INSR ITGB1 ITGB2 ITGB4 ITPKA ITPKB KCNE1 KCNE4 KCNQ2 KIT KLF5 KRT18 LCK LMNA LMNB1 MARCKS MBP MGMT MTOR MYLK MYOD1 NCF1 NFATC1 NFE2L2 NFKBIA NOS1 NR1H2 NRGN NUMB OGG1 OPRD1 PA2G4 PAM PDLIM7 PEA15 PEBP1 PFKFB1 PFKFB2 PICK1 PLCB1 PLD1 PLD2 POLB PPARA PPARG PPP1R14A PRKCZ PRKG1 PSMB4 PTGIR PTPN11 PTPN12 PTPN6 RAC1 RAF1 RALBP1 RARA RBCK1 RGS19 RGS2 RGS7 RHO RHOA RNF31 RPL10 RRAD SACM1L SCRIB SCTR SDC2 SDC4 SDPR SELL SEMG1 SEMG2 SHC1 SLC1A1 SLC6A9 SNAP23 SNAP25 SPAG1 SPP1 SRC STXBP1 STXBP3 SYK TBXA2R TEP1 TERT THOC5 TIAM1 TNNI3 TNNT2 TNP1 TNP2 TOP2A TP53 TRIM29 TRIM41 TRPC3 TRPV6 VCL VTN XK YWHAG YWHAZ 130 interactors: AHR AHSA1 AHSA2 AIP AIPL1 AKT1 AKT2 APAF1 APOB AR ARNTL ASGR1 BIRC5 BRMS1 CALM1 CDC37 CDC37L1 CDK5R1 CDKN2A CERS2 CFTR CHEK1 CHUK CKS1B CKS2 CRNKL1 CSNK2A1 CSNK2A2 DAP3 DNAJC7 EIF2AK1 EIF2AK2 EIF2AK3 EPAS1 EPRS ERBB2 ERN1 ESR1 FAM162A FANCA FANCC FKBP4 FKBP5 FKBP6 FYN GNA12 GSK3B GUCY1B3 GZMA HDAC6 HIF1A HIF3A HSPA1A HSPA8 IKBKB IKBKE IKBKG IP6K2 IRAK1 IRF3 JUN KDR LCK LSM1 MAP3K14 MAP3K3 MAPK1 MCF2 MIS12 MMP2 MS4A2 MTRNR2L1 MYC MYOD1 NDRG1 NOS1 NOS3 NPAS2 NR2C2 NR3C1 NR3C2 NSL1 PAK1 PDPK1 PIM1 PMF1 PPARA PPARD PPID PPIL2 PPP5C PRKCA PRKCD PRKDC PTGDS PTGES3 RAF1 RIPK1 RPS3 RPS3A RUNX1T1 SGTA SIM1 SKP1 SLC2A4 SLC34A1 SMYD2 SMYD3 SNCA SRC ST13 STARD13 STAT3 STIP1 STUB1 SUGT1 SVIL TBK1 TERT TJP1 TNFRSF1A TOMM34 TOMM40 TOMM70A TP53 UBE2N UCHL1 USP19 USP50 WASL
Entrez ID 5578 3320
HPRD ID 01498 00777
Ensembl ID ENSG00000154229 ENSG00000080824
Uniprot IDs P17252 Q7Z727 K9JA46 P07900 Q86SX1
PDB IDs 2ELI 3IW4 4DNL 1BYQ 1OSF 1UY6 1UY7 1UY8 1UY9 1UYC 1UYD 1UYE 1UYF 1UYG 1UYH 1UYI 1UYK 1UYL 1YC1 1YC3 1YC4 1YER 1YES 1YET 2BSM 2BT0 2BUG 2BYH 2BYI 2BZ5 2C2L 2CCS 2CCT 2CCU 2CDD 2FWY 2FWZ 2H55 2JJC 2K5B 2QF6 2QFO 2QG0 2QG2 2UWD 2VCI 2VCJ 2WI1 2WI2 2WI3 2WI4 2WI5 2WI6 2WI7 2XAB 2XDK 2XDL 2XDS 2XDU 2XDX 2XHR 2XHT 2XHX 2XJG 2XJJ 2XJX 2XK2 2YE2 2YE3 2YE4 2YE5 2YE6 2YE7 2YE8 2YE9 2YEA 2YEB 2YEC 2YED 2YEE 2YEF 2YEG 2YEH 2YEI 2YEJ 2YI0 2YI5 2YI6 2YI7 2YJW 2YJX 2YK2 2YK9 2YKB 2YKC 2YKE 2YKI 2YKJ 3B24 3B25 3B26 3B27 3B28 3BM9 3BMY 3D0B 3EKO 3EKR 3FT5 3FT8 3HEK 3HHU 3HYY 3HYZ 3HZ1 3HZ5 3INW 3INX 3K97 3K98 3K99 3MNR 3O0I 3OW6 3OWB 3OWD 3Q6M 3Q6N 3QDD 3QTF 3R4M 3R4N 3R4O 3R4P 3R91 3R92 3RKZ 3RLP 3RLQ 3RLR 3T0H 3T0Z 3T10 3T1K 3T2S 3TUH 3VHA 3VHC 3VHD 4AIF 4AWO 4AWP 4AWQ 4B7P 4EEH 4EFT 4EFU 4EGH 4EGI 4EGK 4FCP 4FCQ 4FCR 4HY6 4JQL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
american  artiodactyla  assigned  block  blot  cattle  chr  conservative  conserved  cow  electrophoresis  erbb2  hybrid  hybridization  localization  localized  means  mink  nf1  pepa  pig  rara  representatives  sheep  southern  swine  synteny  tk1  umph2 
alphascreen  ammp  calnexin  cndp2  combines  hspa5  hspa9  identifier  imbalance  itraq  nfhcc  nonfibrotic  nontumor  p4hb  pdia6  phosphoproteomics  pointed  proteomexchange  proteomics  proteostasis  pxd001253  resident  ser583  txn  ubc  unraveling  vcp 
Tagcloud (Difference) ?
american  artiodactyla  assigned  block  blot  cattle  chr  conservative  conserved  cow  electrophoresis  erbb2  hybrid  hybridization  localization  localized  means  mink  nf1  pepa  pig  rara  representatives  sheep  southern  swine  synteny  tk1  umph2 
alphascreen  ammp  calnexin  cndp2  combines  hspa5  hspa9  identifier  imbalance  itraq  nfhcc  nonfibrotic  nontumor  p4hb  pdia6  phosphoproteomics  pointed  proteomexchange  proteomics  proteostasis  pxd001253  resident  ser583  txn  ubc  unraveling  vcp 
Tagcloud (Intersection) ?