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TRIB3 and RBM48
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
TRIB3
RBM48
Description
tribbles pseudokinase 3
RNA binding motif protein 48
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Plasma Membrane
Nucleoplasm
Spliceosomal Complex
Molecular Function
Transcription Corepressor Activity
Protein Kinase Inhibitor Activity
Protein Binding
ATP Binding
Kinase Activity
Enzyme Binding
Protein Kinase Binding
Protein Serine/threonine Kinase Inhibitor Activity
Mitogen-activated Protein Kinase Kinase Binding
Ubiquitin Protein Ligase Binding
Ubiquitin-protein Transferase Regulator Activity
Ubiquitin Ligase Activator Activity
Nucleic Acid Binding
RNA Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Regulation Of Autophagy
Regulation Of D-glucose Transmembrane Transport
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Insulin Stimulus
Response To Endoplasmic Reticulum Stress
Regulation Of MAP Kinase Activity
Negative Regulation Of MAPK Cascade
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Fatty Acid Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of Insulin Receptor Signaling Pathway
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
MRNA Processing
RNA Splicing
Pathways
PIP3 activates AKT signaling
Activation of AKT2
PPARA activates gene expression
Negative regulation of the PI3K/AKT network
CD28 dependent PI3K/Akt signaling
VEGFR2 mediated vascular permeability
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Drugs
Diseases
GWAS
Information processing speed (
21130836
)
Logical memory (delayed recall) (
29274321
)
Logical memory (immediate recall) (
29274321
)
Hip circumference adjusted for BMI (
34021172
)
Idiopathic dilated cardiomyopathy (
29495422
)
Interacting Genes
100 interacting genes:
ACACA
AKAP8L
AKT1
AKT2
APOBEC3A
APOBEC3C
APP
ARMC7
ATF4
BAG3
BCL6
BFSP2
BMPR2
C21orf58
C22orf39
CBX8
CHAF1A
CLCNKA
COPS6
CTAG1A
CTAG1B
DDIT3
DPPA3
DTX2
EEF1G
EFEMP2
EPHB6
EXOSC5
FAAP20
FAM161A
FAM90A1
FBXO7
GDF9
GIT1
GLIS3
GPATCH2L
GRB2
HAT1
HDAC4
HLA-B
HNRNPF
HOXB5
HOXC8
IL16
INCA1
INO80B
IRX6
KANK2
KAT5
KLHL38
KRT26
LENG1
LMO2
LMO3
MDFI
MDM2
MISP
MYC
OIP5
OSTF1
PADI4
PARD6B
PCSK5
PITX2
PKNOX2
PML
PPP1R26
PRKAB2
PRMT5
PRR19
PSMA3
RBM4
RBM48
RELA
RIDA
RPGRIP1
RPSA
SAMD11
SAXO1
SAXO4
SCNM1
SETDB1
SHFL
SNRPC
SPAG8
SPG21
SUOX
TCF19
TEKT3
TEKT4
TLE5
TRIM55
TRIM63
TTC23
TWIST1
UBTD2
USP20
UTP23
ZNF417
ZNF587
72 interacting genes:
AMOT
ANXA7
APLP1
ATPAF2
BID
BTBD2
CCDC106
CCDC57
CDK5RAP2
CDKN1A
CDKN2C
COX17
COX5B
CSTPP1
EIF1AD
ERH
FAM118B
FAM90A1
FXYD6
GADD45G
GLYAT
GSE1
GSTO1
GYS1
HSF2BP
HSPB1
HSPB3
ID2
JMY
KIF9
KPNA2
MAFG
MAP7D1
MLH1
MLLT3
MNAT1
MPHOSPH6
NTAQ1
NUDT21
OSGEP
PAFAH1B3
PCDHA4
PIBF1
PNP
POLR1C
PPP1R8
PRG2
PRKAB2
PSMD11
RAB27A
RAD51D
RFC5
RPA2
S100Z
SAT1
SCNM1
SERPINB9
SH3GL3
SMN1
SPRED2
SULT1E1
TAF9
TBC1D22B
TEKT4
TK1
TNFSF10
TRDMT1
TRIB3
TSR2
VIM
WDR33
ZNF24
Entrez ID
57761
84060
HPRD ID
09836
13173
Ensembl ID
ENSG00000101255
ENSG00000127993
Uniprot IDs
B4DMM9
J3KR25
Q96RU7
Q5RL73
PDB IDs
7DVQ
Enriched GO Terms of Interacting Partners
?
Nucleus
Protein Binding
Negative Regulation Of Gene Expression
DNA-binding Transcription Factor Binding
Identical Protein Binding
Chromatin Remodeling
Chromatin Organization
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Nucleoplasm
Epigenetic Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Metabolic Process
Regulation Of Gene Expression
Axonemal A Tubule Inner Sheath
Negative Regulation Of DNA-templated Transcription
Regulation Of Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Cytoplasm
Innate Immune Response
PERK-mediated Unfolded Protein Response
CHOP-ATF4 Complex
Axonemal Microtubule
DNA Deamination
Chromatin
RNA Metabolic Process
Response To Radiation
Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Macromolecule Metabolic Process
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Signal Transduction By P53 Class Mediator
Lewy Body Core
Regulation Of Apoptotic Signaling Pathway
Response To Growth Factor
Response To Light Stimulus
Defense Response To Symbiont
Regulation Of Fatty Acid Beta-oxidation
Response To Interleukin-1
Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Generation Of Precursor Metabolites And Energy
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Intracellular Signal Transduction
Defense Response To Other Organism
Regulation Of Macromolecule Metabolic Process
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Translational Initiation
Nucleobase-containing Compound Metabolic Process
Nucleic Acid Metabolic Process
Regulation Of G1/S Transition Of Mitotic Cell Cycle
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