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TRIB3 and SUOX
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
TRIB3
SUOX
Description
tribbles pseudokinase 3
sulfite oxidase
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Plasma Membrane
Mitochondrion
Mitochondrial Intermembrane Space
Mitochondrial Matrix
Molecular Function
Transcription Corepressor Activity
Protein Kinase Inhibitor Activity
Protein Binding
ATP Binding
Kinase Activity
Enzyme Binding
Protein Kinase Binding
Protein Serine/threonine Kinase Inhibitor Activity
Mitogen-activated Protein Kinase Kinase Binding
Ubiquitin Protein Ligase Binding
Ubiquitin-protein Transferase Regulator Activity
Ubiquitin Ligase Activator Activity
Protein Binding
Sulfite Oxidase Activity
Oxidoreductase Activity
Heme Binding
Molybdenum Ion Binding
Molybdopterin Cofactor Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Regulation Of Autophagy
Regulation Of D-glucose Transmembrane Transport
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Insulin Stimulus
Response To Endoplasmic Reticulum Stress
Regulation Of MAP Kinase Activity
Negative Regulation Of MAPK Cascade
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Fatty Acid Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of Insulin Receptor Signaling Pathway
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Sulfur Compound Metabolic Process
Pathways
PIP3 activates AKT signaling
Activation of AKT2
PPARA activates gene expression
Negative regulation of the PI3K/AKT network
CD28 dependent PI3K/Akt signaling
VEGFR2 mediated vascular permeability
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Sulfide oxidation to sulfate
Drugs
{[2-Amino-4-oxo-6,7-di(sulfanyl-κS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum
Diseases
GWAS
Information processing speed (
21130836
)
Logical memory (delayed recall) (
29274321
)
Logical memory (immediate recall) (
29274321
)
Allergic disease (asthma, hay fever or eczema) (
29083406
29785011
)
Anorexia nervosa (
28494655
)
Asthma (
32296059
31959851
31619474
)
Asthma (adult onset) (
31036433
)
Asthma (childhood onset) (
31036433
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Brain morphology (MOSTest) (
32665545
)
Cognitive function (
25644384
)
Eosinophil count (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Gastroesophageal reflux disease (
31527586
)
Intelligence (MTAG) (
29326435
)
Medication use (glucocorticoids) (
31015401
)
Pediatric autoimmune diseases (
26301688
)
Polycystic ovary syndrome (
22885925
)
Refractive error (
32231278
)
Type 1 diabetes (
31152121
18198356
)
Vitiligo (
22951725
)
Interacting Genes
100 interacting genes:
ACACA
AKAP8L
AKT1
AKT2
APOBEC3A
APOBEC3C
APP
ARMC7
ATF4
BAG3
BCL6
BFSP2
BMPR2
C21orf58
C22orf39
CBX8
CHAF1A
CLCNKA
COPS6
CTAG1A
CTAG1B
DDIT3
DPPA3
DTX2
EEF1G
EFEMP2
EPHB6
EXOSC5
FAAP20
FAM161A
FAM90A1
FBXO7
GDF9
GIT1
GLIS3
GPATCH2L
GRB2
HAT1
HDAC4
HLA-B
HNRNPF
HOXB5
HOXC8
IL16
INCA1
INO80B
IRX6
KANK2
KAT5
KLHL38
KRT26
LENG1
LMO2
LMO3
MDFI
MDM2
MISP
MYC
OIP5
OSTF1
PADI4
PARD6B
PCSK5
PITX2
PKNOX2
PML
PPP1R26
PRKAB2
PRMT5
PRR19
PSMA3
RBM4
RBM48
RELA
RIDA
RPGRIP1
RPSA
SAMD11
SAXO1
SAXO4
SCNM1
SETDB1
SHFL
SNRPC
SPAG8
SPG21
SUOX
TCF19
TEKT3
TEKT4
TLE5
TRIM55
TRIM63
TTC23
TWIST1
UBTD2
USP20
UTP23
ZNF417
ZNF587
77 interacting genes:
ACOT11
BAG4
C1D
CAMK2A
CDCA4
CEP76
COA7
COPS8
CRX
CTAG1A
CTAG1B
CYB5R2
DMAP1
DNAAF19
DUSP21
EIF3F
ERICH4
EYA2
FAM217B
FMNL2
FMR1
FNDC3B
GOLGA6L9
HADHB
HMG20A
INCA1
ING5
ISCA2
ITGB3BP
KIAA0753
KRT26
KRT27
KRT34
KRT40
LMO4
MAGEA11
MAGEB10
MBD3L1
MDFI
MED28
MEIS3
MORN3
MYL7
MYO1B
NUP62
PEX19
PIH1D2
POMC
PRRX1
PTTG2
REL
RELA
RHOH
RIMOC1
RINT1
RPLP1
RSKR
RUSC1
SERTAD3
SGTA
SH3BP5L
SNF8
SOHLH1
SPC24
STAT5B
STH
SYNGAP1
TEX12
TRIB3
TSC1
UBQLN2
UBR2
VBP1
VPS28
ZNF143
ZNF576
ZXDC
Entrez ID
57761
6821
HPRD ID
09836
06055
Ensembl ID
ENSG00000101255
ENSG00000139531
Uniprot IDs
B4DMM9
J3KR25
Q96RU7
P51687
PDB IDs
1MJ4
Enriched GO Terms of Interacting Partners
?
Nucleus
Protein Binding
Negative Regulation Of Gene Expression
DNA-binding Transcription Factor Binding
Identical Protein Binding
Chromatin Remodeling
Chromatin Organization
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Nucleoplasm
Epigenetic Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Metabolic Process
Regulation Of Gene Expression
Axonemal A Tubule Inner Sheath
Negative Regulation Of DNA-templated Transcription
Regulation Of Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Cytoplasm
Innate Immune Response
PERK-mediated Unfolded Protein Response
CHOP-ATF4 Complex
Axonemal Microtubule
DNA Deamination
Chromatin
RNA Metabolic Process
Response To Radiation
Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Macromolecule Metabolic Process
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Signal Transduction By P53 Class Mediator
Lewy Body Core
Regulation Of Apoptotic Signaling Pathway
Response To Growth Factor
Response To Light Stimulus
Defense Response To Symbiont
Regulation Of Fatty Acid Beta-oxidation
Response To Interleukin-1
Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Generation Of Precursor Metabolites And Energy
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Intracellular Signal Transduction
Defense Response To Other Organism
Regulation Of Macromolecule Metabolic Process
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Translational Initiation
Protein Binding
Structural Constituent Of Skin Epidermis
Regulation Of Primary Metabolic Process
Regulation Of RNA Metabolic Process
Cytosol
Positive Regulation Of Protein Catabolic Process
Intermediate Filament Cytoskeleton Organization
Keratin Filament
Intermediate Filament-based Process
Intermediate Filament Organization
Regulation Of Nucleobase-containing Compound Metabolic Process
NF-kappaB Complex
Regulation Of DNA-templated Transcription
Cytoplasm
Regulation Of RNA Biosynthetic Process
Nucleus
Regulation Of Protein Catabolic Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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