SUOX and MYO1B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SUOX	MYO1B
Description		sulfite oxidase	myosin IB
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix	Cytoplasm Early Endosome Actin Filament Plasma Membrane Microvillus Brush Border Endosome Membrane Actin Cytoskeleton Myosin Complex Filopodium Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery
	Molecular Function	Protein Binding Sulfite Oxidase Activity Oxidoreductase Activity Heme Binding Molybdenum Ion Binding Molybdopterin Cofactor Binding Metal Ion Binding	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Cadherin Binding Actin Filament Binding
	Biological Process	Sulfur Compound Metabolic Process	Post-Golgi Vesicle-mediated Transport Endocytosis Actin Filament Organization Actin Filament-based Movement Actin Filament Bundle Assembly
Pathways		Sulfide oxidation to sulfate
Drugs		{[2-Amino-4-oxo-6,7-di(sulfanyl-κS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Anorexia nervosa ( 28494655) Asthma ( 32296059 31959851 31619474) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 31527586) Intelligence (MTAG) ( 29326435) Medication use (glucocorticoids) ( 31015401) Pediatric autoimmune diseases ( 26301688) Polycystic ovary syndrome ( 22885925) Refractive error ( 32231278) Type 1 diabetes ( 31152121 18198356) Vitiligo ( 22951725)	Blond vs. brown/black hair color ( 30531825) Gamma glutamyl transferase levels ( 29403010 33339817) Hallux valgus ( 32131869) Liver enzyme levels (alkaline phosphatase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757 33972514) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		77 interacting genes: ACOT11 BAG4 C1D CAMK2A CDCA4 CEP76 COA7 COPS8 CRX CTAG1A CTAG1B CYB5R2 DMAP1 DNAAF19 DUSP21 EIF3F ERICH4 EYA2 FAM217B FMNL2 FMR1 FNDC3B GOLGA6L9 HADHB HMG20A INCA1 ING5 ISCA2 ITGB3BP KIAA0753 KRT26 KRT27 KRT34 KRT40 LMO4 MAGEA11 MAGEB10 MBD3L1 MDFI MED28 MEIS3 MORN3 MYL7 MYO1B NUP62 PEX19 PIH1D2 POMC PRRX1 PTTG2 REL RELA RHOH RIMOC1 RINT1 RPLP1 RSKR RUSC1 SERTAD3 SGTA SH3BP5L SNF8 SOHLH1 SPC24 STAT5B STH SYNGAP1 TEX12 TRIB3 TSC1 UBQLN2 UBR2 VBP1 VPS28 ZNF143 ZNF576 ZXDC	4 interacting genes: POGZ PTEN SUOX USP7
Entrez ID		6821	4430
HPRD ID		06055	08407
Ensembl ID		ENSG00000139531	ENSG00000128641
Uniprot IDs		P51687	B0I1S9 E9PDF6 O43795
PDB IDs		1MJ4
Enriched GO Terms of Interacting Partners?		Protein Binding Structural Constituent Of Skin Epidermis Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Cytosol Positive Regulation Of Protein Catabolic Process Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Regulation Of Nucleobase-containing Compound Metabolic Process NF-kappaB Complex Regulation Of DNA-templated Transcription Cytoplasm Regulation Of RNA Biosynthetic Process Nucleus Regulation Of Protein Catabolic Process	Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Protein Stabilization Regulation Of Ubiquitin-dependent Protein Catabolic Process Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity PML Body Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol Phosphate Phosphatase Activity Central Nervous System Myelin Maintenance Organelle Assembly Rhythmic Synaptic Transmission Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Sulfite Oxidase Activity Molybdenum Ion Binding Molybdopterin Cofactor Binding Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Synaptic Vesicle Clustering Postsynaptic Density Assembly Rhythmic Process Membraneless Organelle Assembly Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Retrograde Transport, Endosome To Golgi Locomotor Rhythm Regulation Of Protein Stability Cellular Response To Electrical Stimulus Ubiquitin Ligase Activator Activity Spindle Assembly Involved In Female Meiosis Regulation Of Proteolysis Postsynaptic Specialization Assembly Neuron-neuron Synaptic Transmission Negative Regulation Of Cell Size Maternal Behavior Presynaptic Membrane Organization Schmidt-Lanterman Incisure Anaphase-promoting Complex Binding Forebrain Morphogenesis Negative Regulation Of Excitatory Postsynaptic Potential Presynaptic Membrane Assembly Monoubiquitinated Protein Deubiquitination DNA Alkylation Repair Transcription-coupled Nucleotide-excision Repair Kinetochore Assembly Phosphatidylinositol-3-phosphate Phosphatase Activity Prepulse Inhibition Meiotic Spindle Assembly
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