SUOX and C1D

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		SUOX	C1D
Name		sulfite oxidase	C1D nuclear receptor corepressor
Structure			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytoplasm Transcription Repressor Complex
	Molecular Function	Protein Binding Sulfite Oxidase Activity Oxidoreductase Activity Heme Binding Molybdenum Ion Binding Molybdopterin Cofactor Binding Metal Ion Binding	DNA Binding Transcription Corepressor Activity RNA Binding Protein Binding Nuclear Receptor Binding
	Biological Process	Sulfur Compound Metabolic Process	Maturation Of 5.8S RRNA RRNA Processing Apoptotic Process Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription
Pathways		Sulfide oxidation to sulfate	Major pathway of rRNA processing in the nucleolus and cytosol Nuclear RNA decay
Drugs		{[2-Amino-4-oxo-6,7-di(sulfanyl-κS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum	None
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011 ) Anorexia nervosa ( 28494655 ) Asthma ( 32296059 31959851 31619474 ) Asthma (adult onset) ( 31036433 ) Asthma (childhood onset) ( 31036433 ) Asthma or allergic disease (pleiotropy) ( 29785011 ) Brain morphology (MOSTest) ( 32665545 ) Cognitive function ( 25644384 ) Eosinophil count ( 32888494 ) Eosinophil percentage of white cells ( 32888494 ) Gastroesophageal reflux disease ( 31527586 ) Intelligence (MTAG) ( 29326435 ) Medication use (glucocorticoids) ( 31015401 ) Pediatric autoimmune diseases ( 26301688 ) Polycystic ovary syndrome ( 22885925 ) Refractive error ( 32231278 ) Type 1 diabetes ( 31152121 18198356 ) Vitiligo ( 22951725 )	Familial lung adenocarcinoma ( 29924316 ) Male-pattern baldness ( 27182965 ) Obstetric antiphospholipid syndrome ( 28424481 ) PR interval ( 32439900 ) Restless legs syndrome ( 29029846 ) Schizophrenia x sex interaction ( 34099189 ) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415 )
Interacting Genes		77 interacting genes: ACOT11 BAG4 C1D CAMK2A CDCA4 CEP76 COA7 COPS8 CRX CTAG1A CTAG1B CYB5R2 DMAP1 DNAAF19 DUSP21 EIF3F ERICH4 EYA2 FAM217B FMNL2 FMR1 FNDC3B GOLGA6L9 HADHB HMG20A INCA1 ING5 ISCA2 ITGB3BP KIAA0753 KRT26 KRT27 KRT34 KRT40 LMO4 MAGEA11 MAGEB10 MBD3L1 MDFI MED28 MEIS3 MORN3 MYL7 MYO1B NUP62 PEX19 PIH1D2 POMC PRRX1 PTTG2 REL RELA RHOH RIMOC1 RINT1 RPLP1 RSKR RUSC1 SERTAD3 SGTA SH3BP5L SNF8 SOHLH1 SPC24 STAT5B STH SYNGAP1 TEX12 TRIB3 TSC1 UBQLN2 UBR2 VBP1 VPS28 ZNF143 ZNF576 ZXDC	15 interacting genes: APP GSC2 IL23R NCOR1 NCOR2 NR1D1 PCBD2 PRKDC SASH1 SH3GLB1 SUOX THRA THRB TSNAX ZGPAT
Entrez ID		6821	10438
HPRD ID		06055	07382
Ensembl ID		ENSG00000139531	ENSG00000197223
Uniprot IDs		P51687	Q13901
PDB IDs		1MJ4	Not available
GO Terms Enriched among Interactors		Protein Binding Structural Constituent Of Skin Epidermis Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Cytosol Positive Regulation Of Protein Catabolic Process Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Regulation Of Nucleobase-containing Compound Metabolic Process NF-kappaB Complex Regulation Of DNA-templated Transcription Cytoplasm Regulation Of RNA Biosynthetic Process Nucleus Regulation Of Protein Catabolic Process	Negative Regulation Of MiRNA Transcription Mating Behavior Sequence-specific DNA Binding Chromatin Thyroid Hormone Receptor Signaling Pathway Female Courtship Behavior Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway DNA Binding Reproductive Behavior Thyroid Hormone Binding Hormone-mediated Signaling Pathway Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Thyroid Hormone Receptor Signaling Pathway Nuclear Receptor Activity Negative Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Regulation Of Female Receptivity Female Mating Behavior Type I Pneumocyte Differentiation Negative Regulation Of Metabolic Process Regulation Of MiRNA Transcription Negative Regulation Of Macromolecule Biosynthetic Process Intracellular Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of MiRNA Metabolic Process Rhythmic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Nuclear Receptor-mediated Signaling Pathway Negative Regulation Of Androgen Receptor Signaling Pathway Regulation Of Macromolecule Biosynthetic Process Regulation Of Phosphorus Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Intracellular Signal Transduction Retinoic Acid Receptor Signaling Pathway Regulation Of Ketone Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Lung Epithelial Cell Differentiation Lung Cell Differentiation Nuclear Body Negative Regulation Of Phosphate Metabolic Process Regulation Of Androgen Receptor Signaling Pathway