NLGN2 and INADL

Number of citations of the paper that reports this interaction (PMID 9647694)
18

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		NLGN2	INADL
Gene Name		neuroligin 2	InaD-like (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Integral Component Of Plasma Membrane Cell Surface Membrane Cell Junction Presynaptic Membrane Synapse Postsynaptic Membrane Inhibitory Synapse	Plasma Membrane Tight Junction Apical Plasma Membrane Protein Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity Neurexin Family Protein Binding Cell Adhesion Molecule Binding Carboxylic Ester Hydrolase Activity	Protein Binding
	Biological Process	Regulation Of Respiratory Gaseous Exchange By Neurological System Process Neuron Cell-cell Adhesion Synapse Assembly Metabolic Process Single Organismal Cell-cell Adhesion Sensory Perception Of Pain Positive Regulation Of Synaptic Transmission, GABAergic Protein Localization To Synapse Locomotory Exploration Behavior Cell-cell Junction Maintenance Regulation Of Synaptic Transmission Synapse Organization Neuromuscular Process Controlling Balance Positive Regulation Of Synapse Assembly Positive Regulation Of Synaptic Transmission, Glutamatergic Terminal Button Organization Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Gephyrin Clustering Postsynaptic Density Protein 95 Clustering Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Positive Regulation Of Excitatory Postsynaptic Membrane Potential	Cell Junction Assembly Intracellular Signal Transduction Cell-cell Junction Organization Tight Junction Assembly
Pathways			Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		7 interactors: DLG2 DLG3 DLG4 INADL NRXN1 NRXN2 NRXN3	28 interactors: ASIC3 BAI1 CACNG2 CLDN1 CNKSR2 CRB3 CRIPT DDX18 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 MPP5 NLGN2 NRXN2 PARD3 PAX6 PRDM16 SCN4A SCN5A TJP3
Entrez ID		57555	10207
HPRD ID		07348	04434
Ensembl ID		ENSG00000169992	ENSG00000132849
Uniprot IDs		Q8NFZ4	Q8NI35
PDB IDs			1VF6 2D92 2DAZ 2DB5 2DLU 2DM8 2DMZ 2EHR
Enriched GO Terms of Interacting Partners?		Receptor Localization To Synapse Vocalization Behavior Protein Localization To Synapse Social Behavior Receptor Clustering Synaptic Transmission Synapse Assembly Neuron Cell-cell Adhesion Protein Localization To Membrane Cell-cell Signaling Postsynaptic Membrane Organization Learning Neuroligin Clustering Synapse Organization Gephyrin Clustering Nucleotide Phosphorylation Learning Or Memory Vocal Learning Regulation Of Grooming Behavior Cognition Postsynaptic Membrane Assembly Membrane Organization Postsynaptic Density Protein 95 Clustering Axon Guidance Neurotransmitter Secretion Auditory Behavior Single-organism Behavior Positive Regulation Of Synapse Maturation Neurological System Process Nervous System Development Regulation Of Neurotransmitter Levels Secretion By Cell Cellular Localization Axonogenesis Regulation Of Synapse Maturation Mechanosensory Behavior Axon Development Neurotransmitter Transport Adult Behavior Cellular Protein Localization Cell Morphogenesis Involved In Neuron Differentiation Behavior Response To Auditory Stimulus Chemotaxis Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Membrane Assembly Secretion Neuron Projection Morphogenesis Membrane Biogenesis Establishment Or Maintenance Of Apical/basal Cell Polarity	Synaptic Transmission Cell-cell Signaling Membrane Depolarization Regulation Of Membrane Potential Neurological System Process Cation Transmembrane Transport Ion Transmembrane Transport Neuron-neuron Synaptic Transmission Regulation Of Ion Transmembrane Transport Metal Ion Transport Ion Transport Cation Transport Signaling Cell Communication Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Transmembrane Transport Regulation Of Ion Transport Neuromuscular Process Regulation Of Neurological System Process Glutamate Receptor Signaling Pathway Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Potassium Ion Import Sensory Perception Of Pain Regulation Of Sensory Perception Of Pain Cell-cell Junction Organization Startle Response Monovalent Inorganic Cation Transport Directional Locomotion Membrane Depolarization During Action Potential Membrane Hyperpolarization Single-organism Behavior Gephyrin Clustering Transport Tight Junction Assembly Nervous System Development Regulation Of Resting Membrane Potential Postsynaptic Membrane Assembly Transmission Of Nerve Impulse Behavior Potassium Ion Transmembrane Transport Protein Localization To Membrane Glial Cell Differentiation Postsynaptic Density Protein 95 Clustering Neurogenesis Membrane Depolarization During Cardiac Muscle Cell Action Potential Apical Junction Assembly Potassium Ion Transport Response To Mechanical Stimulus
Tagcloud ?		17p13 adipocytes array cgh disability duplication dysmorphic encodes encompassing facial fingers fissures fxr2 glut4 hyperpigmentation intellectual mandible nostrils obesity p13 palpebral proposita recognizable referred seizures slc2a4 slender tp53 upturned	10p12 255j24 adopter ak057360 ak078849 apicobasal av260217 bc038105 crb d10s588 drosoplila emp55 flj32798 gukc lin7a lin7b lin7c mpdz mpp2 mpp3 mpp7 mupp1 pals2 patj rp24 scrib scribble sdt stardust
Tagcloud (Difference) ?		17p13 adipocytes array cgh disability duplication dysmorphic encodes encompassing facial fingers fissures fxr2 glut4 hyperpigmentation intellectual mandible nostrils obesity p13 palpebral proposita recognizable referred seizures slc2a4 slender tp53 upturned	10p12 255j24 adopter ak057360 ak078849 apicobasal av260217 bc038105 crb d10s588 drosoplila emp55 flj32798 gukc lin7a lin7b lin7c mpdz mpp2 mpp3 mpp7 mupp1 pals2 patj rp24 scrib scribble sdt stardust
Tagcloud (Intersection) ?