INADL and MAPK12

Number of citations of the paper that reports this interaction (PMID 16637659)
18

Data Source:
HPRD (in vitro)

		INADL	MAPK12
Gene Name		InaD-like (Drosophila)	mitogen-activated protein kinase 12
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Tight Junction Apical Plasma Membrane Protein Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding
	Biological Process	Cell Junction Assembly Intracellular Signal Transduction Cell-cell Junction Organization Tight Junction Assembly	MAPK Cascade Transcription, DNA-templated Regulation Of Transcription, DNA-templated DNA Damage Induced Protein Phosphorylation Organelle Organization Mitochondrion Organization Cell Cycle Arrest Signal Transduction Ras Protein Signal Transduction Muscle Organ Development Positive Regulation Of Peptidase Activity Peptidyl-serine Phosphorylation Muscle Cell Differentiation Myoblast Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Muscle Cell Differentiation
Pathways		Cell junction organization Cell-cell junction organization Tight junction interactions	Signalling to ERKs Signalling by NGF Organelle biogenesis and maintenance CDO in myogenesis NGF signalling via TRKA from the plasma membrane VEGFA-VEGFR2 Pathway Mitochondrial biogenesis DSCAM interactions Activation of PPARGC1A (PGC-1alpha) by phosphorylation Myogenesis Signaling by VEGF NOD1/2 Signaling Pathway Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways p38MAPK events Signalling to RAS Innate Immune System
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		28 interactors: ASIC3 BAI1 CACNG2 CLDN1 CNKSR2 CRB3 CRIPT DDX18 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 MPP5 NLGN2 NRXN2 PARD3 PAX6 PRDM16 SCN4A SCN5A TJP3	25 interactors: DLG1 DLG2 DLG3 DLG4 DUSP1 EEF2K ERBB2IP GRB2 GTF2I HTRA2 INADL MAP2K3 MAP2K4 MAP2K6 MAPKAPK5 MAPT MBP PKN1 RGS3 SH3BP5 SIAH1 SNTA1 SNTB1 SRPK1 TERF1
Entrez ID		10207	6300
HPRD ID		04434	03868
Ensembl ID		ENSG00000132849	ENSG00000188130
Uniprot IDs		Q8NI35	B7Z274 P53778
PDB IDs		1VF6 2D92 2DAZ 2DB5 2DLU 2DM8 2DMZ 2EHR	1CM8
Enriched GO Terms of Interacting Partners?		Synaptic Transmission Cell-cell Signaling Membrane Depolarization Regulation Of Membrane Potential Neurological System Process Cation Transmembrane Transport Ion Transmembrane Transport Neuron-neuron Synaptic Transmission Regulation Of Ion Transmembrane Transport Metal Ion Transport Ion Transport Cation Transport Signaling Cell Communication Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Transmembrane Transport Regulation Of Ion Transport Neuromuscular Process Regulation Of Neurological System Process Glutamate Receptor Signaling Pathway Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Potassium Ion Import Sensory Perception Of Pain Regulation Of Sensory Perception Of Pain Cell-cell Junction Organization Startle Response Monovalent Inorganic Cation Transport Directional Locomotion Membrane Depolarization During Action Potential Membrane Hyperpolarization Single-organism Behavior Gephyrin Clustering Transport Tight Junction Assembly Nervous System Development Regulation Of Resting Membrane Potential Postsynaptic Membrane Assembly Transmission Of Nerve Impulse Behavior Potassium Ion Transmembrane Transport Protein Localization To Membrane Glial Cell Differentiation Postsynaptic Density Protein 95 Clustering Neurogenesis Membrane Depolarization During Cardiac Muscle Cell Action Potential Apical Junction Assembly Potassium Ion Transport Response To Mechanical Stimulus	Receptor Localization To Synapse Regulation Of Phosphorus Metabolic Process Protein Localization To Synapse Regulation Of Catalytic Activity Regulation Of MAP Kinase Activity Regulation Of Cellular Protein Metabolic Process Establishment Or Maintenance Of Apical/basal Cell Polarity Regulation Of Phosphorylation Regulation Of Protein Kinase Activity Signaling Regulation Of Intracellular Signal Transduction Regulation Of Protein Phosphorylation Regulation Of Kinase Activity Regulation Of Protein Metabolic Process Cell Communication Regulation Of Metabolic Process Regulation Of MAPK Cascade Muscle System Process Receptor Clustering Activation Of Protein Kinase Activity Activation Of MAPK Activity Nucleotide Phosphorylation Response To Stimulus Regulation Of Cellular Process Phosphorylation Intracellular Signal Transduction Signal Transduction Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of MAP Kinase Activity Muscle Contraction Cellular Response To Sorbitol MAPK Cascade Positive Regulation Of Protein Polymerization Positive Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Phosphate-containing Compound Metabolic Process Positive Regulation Of Catalytic Activity Axonogenesis Positive Regulation Of Transferase Activity Regulation Of Signaling Axon Development Cell Morphogenesis Involved In Neuron Differentiation Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Positive Regulation Of Apoptotic Process
Tagcloud ?		10p12 255j24 adopter ak057360 ak078849 apicobasal av260217 bc038105 crb d10s588 drosoplila emp55 flj32798 gukc lin7a lin7b lin7c mpdz mpp2 mpp3 mpp7 mupp1 pals2 patj rp24 scrib scribble sdt stardust	6j acpp canonical carcinogenic cdk5 delineate e2f6 elf1 glands gprc5a hindered ingenuity ionizing ipa map2 mapped microarray nab2 persistently perturbed plcg1 ppp4c radiation runx1 scarcity sema4d stathmin1 surgically undertook
Tagcloud (Difference) ?		10p12 255j24 adopter ak057360 ak078849 apicobasal av260217 bc038105 crb d10s588 drosoplila emp55 flj32798 gukc lin7a lin7b lin7c mpdz mpp2 mpp3 mpp7 mupp1 pals2 patj rp24 scrib scribble sdt stardust	6j acpp canonical carcinogenic cdk5 delineate e2f6 elf1 glands gprc5a hindered ingenuity ionizing ipa map2 mapped microarray nab2 persistently perturbed plcg1 ppp4c radiation runx1 scarcity sema4d stathmin1 surgically undertook
Tagcloud (Intersection) ?