CGN and F11R

Number of citations of the paper that reports this interaction (PubMedID 10877843)
0

Data Source:
HPRD (in vivo, in vitro)

		CGN	F11R
Description		cingulin	F11 receptor
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Myosin Complex Cell Junction Anchoring Junction	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Membrane Cell Junction Protein-containing Complex Extracellular Exosome Tight Junction Anchoring Junction
	Molecular Function	Actin Binding Protein Binding Microtubule Binding Cadherin Binding	Virus Receptor Activity Integrin Binding Protein Binding PDZ Domain Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Microtubule Cytoskeleton Organization	Regulation Of Cytokine Production System Process Inflammatory Response Cell Adhesion Leukocyte Cell-cell Adhesion Regulation Of Cell Shape Cell Differentiation Epithelial Cell Differentiation Actomyosin Structure Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Rho Protein Signal Transduction Maintenance Of Blood-brain Barrier Memory T Cell Extravasation Symbiont Entry Into Host Cell Intestinal Absorption Leukocyte Migration Regulation Of Cytoskeleton Organization Negative Regulation Of Stress Fiber Assembly Regulation Of Biological Quality Cellular Response To Mechanical Stimulus Protein Localization To Plasma Membrane Establishment Of Endothelial Intestinal Barrier Regulation Of Membrane Permeability Cell-cell Adhesion Positive Regulation Of Platelet Aggregation Protein Localization To Bicellular Tight Junction Positive Regulation Of Establishment Of Endothelial Barrier Regulation Of Bicellular Tight Junction Assembly
Pathways		TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Cell surface interactions at the vascular wall Integrin cell surface interactions TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Tight junction interactions
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Inflammatory bowel disease ( 23128233) Night sleep phenotypes ( 27126917)
Interacting Genes		10 interacting genes: ARHGEF2 CDC42 F11R LNX1 PPP1R13B RNF10 TJP1 TJP2 TP53BP2 YWHAG	30 interacting genes: AFDN ASIP BDNF CAMLG CASK CGN CSNK2A1 F2RL2 ITGAL JAGN1 MARCHF2 MMP14 MPDZ MYADM PARD3 PEX19 PGAP2 PICK1 PRKCA PTPRB RABAC1 SGTA SLC30A2 SLC35A1 SNAP47 STRIT1 TJP1 TMEM100 TMEM147 TMEM86B
Entrez ID		57530	50848
HPRD ID		10827	12038
Ensembl ID		ENSG00000143375	ENSG00000158769
Uniprot IDs		Q9P2M7	Q6FIB4 Q9Y624
PDB IDs			1NBQ 3EOY 3TSZ 4ODB
Enriched GO Terms of Interacting Partners?		Establishment Of Endothelial Intestinal Barrier Protein Localization To Cell-cell Junction Maintenance Of Blood-brain Barrier Tight Junction Establishment Of Endothelial Barrier Bicellular Tight Junction Endothelial Cell Development Positive Regulation Of Blood-brain Barrier Permeability Protein Localization To Bicellular Tight Junction Regulation Of Blood-brain Barrier Permeability Protein Localization To Cell Junction Regulation Of Stress Fiber Assembly Positive Regulation Of Vascular Permeability Regulation Of Supramolecular Fiber Organization Epithelial Cell Development Anchoring Junction Regulation Of Bicellular Tight Junction Assembly Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Supramolecular Fiber Organization Cell Junction Organization Cell-cell Junction Organization Positive Regulation Of Cell Adhesion Intestinal Absorption Anatomical Structure Homeostasis Tissue Homeostasis Negative Regulation Of Stress Fiber Assembly Regulation Of Cytoskeleton Organization Intracellular Protein Localization Cell Junction Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Vascular Permeability Regulation Of Actin Filament Organization Adherens Junction Organization Negative Regulation Of Cellular Component Organization Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Protein-containing Complex Cadherin Binding Regulation Of Membrane Permeability Circulatory System Process Regulation Of Cell Adhesion Positive Regulation Of Cell-cell Adhesion P53 Binding Regulation Of Actin Cytoskeleton Organization Digestive System Process Ubiquitin Protein Ligase Activity Actin Cytoskeleton Organization PDZ Domain Binding Regulation Of Actin Filament-based Process Apical Part Of Cell GBD Domain Binding	Localization Within Membrane Plasma Membrane Membrane Cell-cell Junction Organization Establishment Of Protein Localization To Membrane Cell-cell Junction Assembly Cell Junction Assembly Cell Junction Organization Protein Insertion Into ER Membrane Cell Junction Cellular Localization Tight Junction Establishment Of Endothelial Barrier Endothelial Cell Development Bicellular Tight Junction Tight Junction Assembly Tight Junction Organization Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Protein Localization To Membrane Regulation Of Insulin Secretion Protein Insertion Into Membrane Cellular Component Maintenance Establishment Of Protein Localization Establishment Of Endothelial Intestinal Barrier Tail-anchored Membrane Protein Insertion Into ER Membrane Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Peptide Hormone Secretion Protein Targeting Cell-cell Junction Regulation Of Actin Filament-based Process Cell Adhesion Molecule Binding Cell-cell Junction Maintenance Signaling Receptor Binding Anchoring Junction Intracellular Protein Localization Regulation Of Protein Localization Positive Regulation Of Calcium Ion Import Regulation Of Cell Junction Assembly Regulation Of Hormone Secretion Regulation Of Protein Secretion Glial Cell Migration Apical Junction Complex Regulation Of Actin Filament Organization Negative Regulation Of Protein Catabolic Process Melanocortin Receptor Binding Epithelial Cell Development Cellular Response To Genistein Negative Regulation Of GDF15-GFRAL Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?