CGN and F11R

Number of citations of the paper that reports this interaction (PMID 10877843)
62

Data Source:
HPRD (in vitro, in vivo)

		CGN	F11R
Gene Name		cingulin	F11 receptor
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Tight Junction Myosin Complex Cell Junction	Plasma Membrane Cell-cell Junction Tight Junction Microtubule Cytoskeleton Integral Component Of Membrane Cell Junction Cytoplasmic Vesicle Slit Diaphragm Extracellular Vesicular Exosome
	Molecular Function	Motor Activity Actin Binding Protein Binding Microtubule Binding	Protein Binding PDZ Domain Binding
	Biological Process	Microtubule Cytoskeleton Organization Epithelial Cell Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Biological_process Metabolic Process Tight Junction Assembly	Inflammatory Response Cell Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Blood Coagulation Response To Radiation Viral Process Extracellular Matrix Organization Actomyosin Structure Organization Positive Regulation Of Rap GTPase Activity Negative Regulation Of Rho GTPase Activity Cell Junction Assembly Cell-cell Junction Organization Positive Regulation Of Blood Pressure Intestinal Absorption Leukocyte Migration Tight Junction Assembly Establishment Of Protein Localization To Plasma Membrane Establishment Of Endothelial Intestinal Barrier Regulation Of Membrane Permeability Regulation Of Actin Cytoskeleton Reorganization
Pathways		Loss of Function of TGFBR2 in Cancer TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) TGFBR2 MSI Frameshift Mutants in Cancer SMAD2/3 Phosphorylation Motif Mutants in Cancer Loss of Function of SMAD2/3 in Cancer TGFBR2 Kinase Domain Mutants in Cancer SMAD2/3 MH2 Domain Mutants in Cancer Loss of Function of SMAD4 in Cancer TGFBR1 KD Mutants in Cancer TGFBR1 LBD Mutants in Cancer Loss of Function of TGFBR1 in Cancer Signaling by TGF-beta Receptor Complex Signaling by TGF-beta Receptor Complex in Cancer SMAD4 MH2 Domain Mutants in Cancer	Loss of Function of TGFBR2 in Cancer Cell junction organization TGFBR2 MSI Frameshift Mutants in Cancer TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) SMAD2/3 Phosphorylation Motif Mutants in Cancer Tight junction interactions Loss of Function of SMAD2/3 in Cancer TGFBR2 Kinase Domain Mutants in Cancer SMAD2/3 MH2 Domain Mutants in Cancer Loss of Function of SMAD4 in Cancer TGFBR1 KD Mutants in Cancer TGFBR1 LBD Mutants in Cancer Loss of Function of TGFBR1 in Cancer Cell surface interactions at the vascular wall Cell-cell junction organization Signaling by TGF-beta Receptor Complex Signaling by TGF-beta Receptor Complex in Cancer Integrin cell surface interactions SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		6 interactors: ARHGEF2 F11R LNX1 TJP1 TJP2 YWHAG	16 interactors: ASIP BDNF CASK CGN CSNK2A1 F2RL2 ITGAL MLLT4 MPDZ PARD3 PEX19 PICK1 PRKCA PTPRB SGTA TJP1
Entrez ID		57530	50848
HPRD ID		10827	12038
Ensembl ID		ENSG00000143375	ENSG00000158769
Uniprot IDs		Q9P2M7	B7Z941 Q6FIB4 Q9Y624
PDB IDs			1NBQ 3EOY 3TSZ
Enriched GO Terms of Interacting Partners?		Establishment Of Endothelial Intestinal Barrier Establishment Of Endothelial Barrier Endothelial Cell Development Endothelial Cell Differentiation Endothelium Development Epithelial Cell Development Intestinal Absorption Hippo Signaling Regulation Of Membrane Permeability Apoptotic Process Programmed Cell Death Cell Death Death Response To Organic Substance Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Epithelial Cell Differentiation Cell-cell Signaling Involved In Cell-cell Junction Organization Cell Differentiation Digestion Cell-cell Junction Assembly Intracellular Signal Transduction Cellular Response To Organic Substance Cellular Response To Muramyl Dipeptide Membrane Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Response To Magnetism Cell Junction Assembly Regulation Of Organelle Organization Cell-cell Junction Organization Epithelium Development Response To Abiotic Stimulus Anatomical Structure Development Regulation Of Rho GTPase Activity Regulation Of Response To Osmotic Stress Cellular Hyperosmotic Response Blood Circulation Signal Transduction Cellular Response To Peptide Regulation Of Rho Protein Signal Transduction Apoptotic Signaling Pathway Developmental Process Cellular Protein Localization Negative Regulation Of Vascular Permeability Negative Regulation Of Rho GTPase Activity Signaling Negative Regulation Of Necroptotic Process Cell Communication Establishment Of Protein Localization Positive Regulation Of Rap GTPase Activity	Cell Junction Assembly Cell-cell Junction Organization Cell-cell Junction Assembly Establishment Of Endothelial Intestinal Barrier Signal Transduction Epithelial Cell Development Membrane Organization Cell-cell Signaling Signaling Cell Communication Anatomical Structure Development Protein Localization To Membrane Cell Development Cellular Response To Stimulus Developmental Process Establishment Of Endothelial Barrier Epithelial Cell Differentiation Cell Surface Receptor Signaling Pathway Endothelial Cell Development Tight Junction Assembly Regulation Of Body Fluid Levels Cellular Response To Growth Factor Stimulus Epithelial Cell Morphogenesis Epithelium Development Anatomical Structure Morphogenesis Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Wound Healing Response To Growth Factor Receptor Clustering Tissue Development G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling Involved In Cell-cell Junction Organization Response To Anesthetic Negative Regulation Of Lipid Binding Positive Regulation Of Dense Core Granule Biogenesis Response To Fluoxetine Response To L-glutamate Cell Differentiation Cell Adhesion Chaperone-mediated Protein Folding Negative Regulation Of Synaptic Transmission Cellular Response To Organic Substance Response To Wounding Response To Stimulus Locomotion Apical Junction Assembly Cell Morphogenesis Involved In Differentiation Endothelial Cell Differentiation Cellular Response To Carbohydrate Stimulus Multicellular Organismal Development
Tagcloud ?		ac attenuate believed blots caspase cerebellar cho cytochrome cytosol cytosolic devd ensuing extracts fmk granule hydroxydopamine involves lacking laddering mitochondria neurotoxicity ohda pna points precedes protease reveal ultimately zvad
Tagcloud (Difference) ?		ac attenuate believed blots caspase cerebellar cho cytochrome cytosol cytosolic devd ensuing extracts fmk granule hydroxydopamine involves lacking laddering mitochondria neurotoxicity ohda pna points precedes protease reveal ultimately zvad
Tagcloud (Intersection) ?