SDHD

Description		succinate dehydrogenase complex subunit D
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Envelope Mitochondrial Inner Membrane Membrane Respiratory Chain Complex II (succinate Dehydrogenase)
	Molecular Function	Protein Binding Succinate Dehydrogenase (quinone) Activity Electron Transfer Activity Heme Binding Metal Ion Binding Ubiquinone Binding
	Biological Process	Tricarboxylic Acid Cycle Mitochondrial Electron Transport, Succinate To Ubiquinone Proton Motive Force-driven Mitochondrial ATP Synthesis Regulation Of Catecholamine Secretion Cellular Response To Hypoxia
Pathways		Respiratory electron transport Citric acid cycle (TCA cycle) Maturation of TCA enzymes and regulation of TCA cycle
Drugs		Hexachlorophene 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Ubiquinone Q1
Diseases		Carcinoid
GWAS		Brain morphology (MOSTest) ( 32665545) General risk tolerance (MTAG) ( 30643258) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		5 interacting genes: F2RL1 GPR35 MTNR1B RHBDD2 SLC13A1
Entrez ID		6392
HPRD ID		04069
Ensembl ID		ENSG00000204370
Uniprot IDs		A0A0S2Z4H7 A0A0S2Z4J3 O14521
PDB IDs		8GS8
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Insulin Secretion Negative Regulation Of Peptide Secretion G Protein-coupled Receptor Activity Negative Regulation Of Protein Secretion Negative Regulation Of Hormone Secretion Negative Regulation Of Transport Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Renin Secretion Into Blood Stream Proteinase-activated Receptor Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Blood Vessel Diameter Maintenance Negative Regulation Of Secretion By Cell Positive Regulation Of Glomerular Filtration G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Protein Transport Regulation Of Renin Secretion Into Blood Stream Regulation Of Tube Size Positive Regulation Of Eosinophil Degranulation Negative Regulation Of Establishment Of Protein Localization Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Sodium:sulfate Symporter Activity Monoatomic Anion:sodium Symporter Activity Regulation Of Insulin Secretion Negative Regulation Of Secretion Positive Regulation Of Killing Of Cells Of Another Organism Melatonin Receptor Activity Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Regulation Of Peptide Hormone Secretion Mature Conventional Dendritic Cell Differentiation Thrombin-activated Receptor Activity Regulation Of Neuronal Action Potential Negative Regulation Of Protein Localization Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Cytotoxicity Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Positive Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Regulation Of Hormone Secretion Regulation Of Protein Secretion Vascular Process In Circulatory System C-X-C Chemokine Receptor Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Secondary Active Sulfate Transmembrane Transporter Activity Signal Recognition Particle Binding Regulation Of Glomerular Filtration Thrombin-activated Receptor Signaling Pathway
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