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RBM10 and TLE5
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
RBM10
TLE5
Description
RNA binding motif protein 10
TLE family member 5, transcriptional modulator
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Nuclear Speck
Protein-containing Complex
Nucleus
Molecular Function
Nucleic Acid Binding
RNA Binding
Protein Binding
Zinc Ion Binding
MiRNA Binding
Identical Protein Binding
Metal Ion Binding
Transcription Corepressor Activity
Protein Binding
Identical Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
MRNA Splicing, Via Spliceosome
MRNA Processing
Negative Regulation Of Cell Population Proliferation
RNA Splicing
Negative Regulation Of MRNA Splicing, Via Spliceosome
3'-UTR-mediated MRNA Stabilization
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Vascular Associated Smooth Muscle Cell Apoptotic Process
Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process
Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process
Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Ribosomal Large Subunit Export From Nucleus
Negative Regulation Of Transcription By RNA Polymerase II
Skeletal System Development
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Gene Expression
Wnt Signaling Pathway
Regulation Of Growth
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of Response To Cytokine Stimulus
Response To Interleukin-1
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Anoikis
Pathways
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Repression of WNT target genes
Drugs
Diseases
TARP syndrome
GWAS
Interacting Genes
73 interacting genes:
AKAP9
ATN1
BAHD1
BEND7
CASK
CBLL1
CCAR1
CEP70
CPSF7
CSNK2A1
DDX17
DDX5
FAM124A
GTSE1
HNRNPH2
HNRNPK
HNRNPLL
IK
KHDRBS2
KLF1
MAPRE2
MBD6
MDM2
MEOX2
MIR106B
MIR107
MIR128-1
MIR21
MIR214
MIRLET7A1
MIRLET7A3
MIRLET7D
MIRLET7E
MIRLET7G
MIRLET7I
NDEL1
NIN
PATZ1
PCBP1
PRC1
PRCC
PRDM14
PRR20A
PTBP1
PTBP2
RBM12
RBM12B
RBM14
RBM4
RBM7
RBMY1F
RNF10
SF1
SF3A1
SF3B2
SF3B4
SLAIN1
SNRPA
SNU13
SREK1
SRSF6
TBC1D22B
THAP1
TLE5
U2AF1
UBQLN4
ZBTB24
ZFP64
ZNF275
ZNF317
ZNF408
ZNF473
ZNF526
363 interacting genes:
ABI2
ACTMAP
AEN
AGR2
AIRIM
AKAP8L
ANAPC11
ANKRD11
AR
ARHGAP32
ARX
ASB3
ATN1
ATOSB
ATP6V0D1
BAG4
BAHD1
BCL6
BHLHE40
BIRC7
BPIFA1
BYSL
C10orf55
C14orf119
C1orf216
C1orf94
C7orf57
CABP2
CABP4
CABP5
CALCOCO2
CAPN1
CARD9
CATSPERT
CCDC120
CCDC57
CCL7
CCNJL
CCNK
CFAP206
CFAP68
CIB3
CLIC3
CLIP3
CNFN
COA7
CPSF7
CRACR2A
CSNK1E
CSNK2A1
CSTF2
CSTF2T
CT55
CTBP2
CYSRT1
DAZAP2
DCUN1D1
DDX6
DGCR6
DIP2A
DMRT2
DMRT3
DMRTB1
DNMT3L
DOK6
DVL2
DVL3
DYDC1
EAF1
EAF2
EFEMP2
EFHC1
EIF1AD
EIF4E2
ERF
EXOSC5
EYA2
FAM124A
FAM124B
FAM168B
FAM217B
FAM90A1
FANCG
FBF1
FCHSD2
FHL3
FOSB
FOXD2
FOXN1
FOXP2
FRS3
FSD2
FXR1
FXR2
GABARAP
GATA1
GCC1
GEM
GFAP
GFI1B
GIGYF1
GLIS2
GLRX3
GOLGA2
GOLGA6L9
GORASP2
GPANK1
GPATCH2L
GRAP2
GRB2
GRN
GTF2E1
GYS1
HDAC4
HDHD3
HELT
HEXIM2
HGS
HHEX
HMGB1
HNF1A
HNRNPF
HNRNPH2
HNRNPK
HNRNPLL
HOMEZ
HOXA1
HOXB5
HOXC8
HOXC9
IKZF3
INO80B
INO80E
INPP5J
IRX2
IRX6
KANK2
KDM1A
KIFC3
KLF1
KLF4
KLHDC7B
KRT13
KRT15
KRT31
KRT34
KRT35
KRT40
KRTAP1-1
KRTAP10-11
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP11-1
KRTAP12-2
KRTAP13-2
KRTAP13-3
KRTAP17-1
KRTAP19-5
KRTAP19-7
KRTAP6-2
KRTAP6-3
KRTAP7-1
KRTAP8-1
L3MBTL2
LDLR
LDOC1
LENG8
LINC00526
LMO1
LMO2
LMO4
LSM2
LZTS2
MAGOHB
MAPK1
MAPK14
MAPRE3
MBNL1
MCRS1
MDFI
MECOM
MED12L
MED25
MED31
MED4
MEIS3
MFAP1
MIA2
MIIP
MKRN3
MLH1
MLLT6
MLX
MORF4L1
MORF4L2
MSS51
MSX1
MSX2
MTUS2
MVP
MYF5
MYH7B
MYO15B
MYOG
NAB2
NAF1
NBPF19
NCDN
NDOR1
NDUFB7
NEK6
NLGN3
NOTCH2NLA
NTAQ1
NUDT22
NUTF2
NUTM1
OLIG3
OSGIN1
OXER1
P4HA3
PARVG
PATZ1
PCBP1
PCSK5
PFDN5
PHF1
PICK1
PITX1
PITX2
PLAGL1
POLR1C
POU2F1
PPP1R16A
PPP1R16B
PRDM1
PRDM14
PRDM6
PRKAA1
PRKAA2
PRKAB2
PROP1
PRPF31
PRR3
PRR35
PSMB1
PSMB4
PSMF1
PTRH2
QARS1
RAD51D
RBM10
RBPMS
REL
RELA
RFX6
RHOXF2
RIBC1
RIMBP3
RNF31
RORB
RPL18A
RUNX1
RUSC1
SAT1
SCNM1
SDCBP
SERTAD3
SET
SF3B4
SH2B2
SH3GL3
SHFL
SHISA6
SIX1
SIX2
SIX3
SIX6
SKIL
SKP2
SMAD3
SMAD4
SMARCB1
SMARCD1
SNCAIP
SNRPA
SNRPC
SOHLH1
SPATA25
SPG21
SPMIP9
SRPK2
SSC4D
STK16
STX11
SUFU
SUPT5H
TBX3
TBX6
TCEANC
TCF4
TCF7L2
TEAD4
TENT5B
TFAP2D
THAP7
TIGD3
TMCC2
TNS2
TOX3
TRAF1
TRAF2
TRIB3
TRIM26
TRIM27
TRIM41
TRIP6
TRMT2A
TSC1
TSC22D4
TSEN15
TSGA10
TSGA10IP
TSSK3
TTC23
U2AF2
UBAP2
UBE2H
UBL5
UBXN11
USP2
USP54
VEZF1
VGLL1
VIM
VPS37B
VPS37C
YPEL3
YTHDF1
ZBTB16
ZBTB24
ZBTB47
ZFHX3
ZGPAT
ZIC1
ZMYND12
ZNF330
ZNF34
ZNF383
ZNF408
ZNF414
ZNF417
ZNF467
ZNF48
ZNF503
ZNF524
ZNF576
ZNF688
ZNF792
ZNF835
ZRANB1
Entrez ID
8241
166
HPRD ID
02095
02556
Ensembl ID
ENSG00000182872
ENSG00000104964
Uniprot IDs
A0A0S2Z4W4
A0A0S2Z4X1
P98175
Q08117
PDB IDs
2LXI
2M2B
2MXV
2MXW
5ZSW
5ZSY
Enriched GO Terms of Interacting Partners
?
MRNA Processing
MRNA Metabolic Process
Regulation Of RNA Splicing
Nucleic Acid Binding
RNA Splicing
Regulatory NcRNA-mediated Gene Silencing
MiRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
RNA Processing
Post-transcriptional Gene Silencing
Spliceosomal Complex
MRNA Splicing, Via Spliceosome
MRNA Base-pairing Post-transcriptional Repressor Activity
RNA Splicing, Via Transesterification Reactions
RNA Metabolic Process
Regulation Of MRNA Metabolic Process
Regulation Of MRNA Splicing, Via Spliceosome
RNA Binding
MRNA Binding
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Regulation Of MRNA Processing
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Nucleoplasm
Nuclear Speck
Regulation Of Macromolecule Metabolic Process
Nucleic Acid Metabolic Process
Regulation Of Primary Metabolic Process
Nucleus
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Extracellular Vesicle
Negative Regulation Of Translation
Regulation Of Metabolic Process
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Metabolic Process
MiRNA-mediated Gene Silencing By MRNA Destabilization
Ribonucleoprotein Complex
Pre-mRNA Binding
MRNA 3'-UTR Binding
Post-transcriptional Regulation Of Gene Expression
U2-type Precatalytic Spliceosome
Negative Regulation Of RNA Splicing
Microtubule Nucleation
Protein Binding
Regulation Of RNA Metabolic Process
Nucleus
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of Gene Expression
Regulation Of Primary Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Negative Regulation Of RNA Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Chromatin
Positive Regulation Of RNA Metabolic Process
DNA-binding Transcription Factor Activity
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Intermediate Filament
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
DNA Binding
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Nucleoplasm
Negative Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Metabolic Process
Transcription Regulator Complex
Negative Regulation Of Macromolecule Biosynthetic Process
Sequence-specific DNA Binding
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Sequence-specific Double-stranded DNA Binding
Negative Regulation Of Metabolic Process
Keratin Filament
Identical Protein Binding
Transcription Cis-regulatory Region Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Transcription Corepressor Binding
Cellular Developmental Process
Cell Differentiation
Pattern Specification Process
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
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