RBM10 and NIN

Number of citations of the paper that reports this interaction (PubMedID 30217970)
38

Data Source:
BioGRID (two hybrid)

		RBM10	NIN
Description		RNA binding motif protein 10	ninein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Speck Protein-containing Complex	Pericentriolar Material Spindle Pole Nucleoplasm Nucleolus Cytoplasm Centrosome Centriole Cytoskeleton Microtubule Cytoplasmic Microtubule Plasma Membrane Axon Dendrite Ciliary Basal Body Axonal Growth Cone Apical Part Of Cell Mitotic Spindle Mitotic Spindle Pole Ciliary Transition Fiber Centriolar Subdistal Appendage
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding MiRNA Binding Identical Protein Binding Metal Ion Binding	Nucleotide Binding Calcium Ion Binding Protein Binding GTP Binding Microtubule Minus-end Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II MRNA Splicing, Via Spliceosome MRNA Processing Negative Regulation Of Cell Population Proliferation RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome 3'-UTR-mediated MRNA Stabilization Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Vascular Associated Smooth Muscle Cell Apoptotic Process Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Ribosomal Large Subunit Export From Nucleus	Intracellular Protein Localization Centriole-centriole Cohesion Corpus Callosum Morphogenesis Corticospinal Tract Morphogenesis Microtubule Anchoring At Centrosome Collateral Sprouting Positive Regulation Of Axonogenesis Centrosome Localization Centrosome-templated Microtubule Nucleation
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases		TARP syndrome
GWAS			Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 34315874) Asthma (time to childhood onset) x early life tobacco smoke interaction ( 31379025) Cognitive performance ( 20125193) Diastolic blood pressure ( 30578418) Lupus nephritis in systemic lupus erythematosus ( 24925725) Mean platelet volume ( 27863252) Periodontal disease-related phenotype (Socransky) ( 24347629) Pulse pressure ( 30578418) Rectal cancer ( 33632709) Refractive error ( 32231278) Schizophrenia ( 33169155) Stroke ( 32693751) Systolic blood pressure ( 30578418)
Interacting Genes		73 interacting genes: AKAP9 ATN1 BAHD1 BEND7 CASK CBLL1 CCAR1 CEP70 CPSF7 CSNK2A1 DDX17 DDX5 FAM124A GTSE1 HNRNPH2 HNRNPK HNRNPLL IK KHDRBS2 KLF1 MAPRE2 MBD6 MDM2 MEOX2 MIR106B MIR107 MIR128-1 MIR21 MIR214 MIRLET7A1 MIRLET7A3 MIRLET7D MIRLET7E MIRLET7G MIRLET7I NDEL1 NIN PATZ1 PCBP1 PRC1 PRCC PRDM14 PRR20A PTBP1 PTBP2 RBM12 RBM12B RBM14 RBM4 RBM7 RBMY1F RNF10 SF1 SF3A1 SF3B2 SF3B4 SLAIN1 SNRPA SNU13 SREK1 SRSF6 TBC1D22B THAP1 TLE5 U2AF1 UBQLN4 ZBTB24 ZFP64 ZNF275 ZNF317 ZNF408 ZNF473 ZNF526	17 interacting genes: ABI1 AUNIP AURKA BICD1 GSK3B GTSE1 KLC1 PIAS1 PRKACA PRPF6 RBM10 RTRAF SNW1 SUMO1 UBE2I UTP14A YWHAE
Entrez ID		8241	51199
HPRD ID		02095	09785
Ensembl ID		ENSG00000182872	ENSG00000100503
Uniprot IDs		A0A0S2Z4W4 A0A0S2Z4X1 P98175	C9J066 E9PN67 Q5XUU0 Q8N4C6
PDB IDs		2LXI 2M2B 2MXV 2MXW 5ZSW 5ZSY
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process Regulation Of RNA Splicing Nucleic Acid Binding RNA Splicing Regulatory NcRNA-mediated Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RNA Processing Post-transcriptional Gene Silencing Spliceosomal Complex MRNA Splicing, Via Spliceosome MRNA Base-pairing Post-transcriptional Repressor Activity RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome RNA Binding MRNA Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleoplasm Nuclear Speck Regulation Of Macromolecule Metabolic Process Nucleic Acid Metabolic Process Regulation Of Primary Metabolic Process Nucleus Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Extracellular Vesicle Negative Regulation Of Translation Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Ribonucleoprotein Complex Pre-mRNA Binding MRNA 3'-UTR Binding Post-transcriptional Regulation Of Gene Expression U2-type Precatalytic Spliceosome Negative Regulation Of RNA Splicing Microtubule Nucleation	Regulation Of Nucleocytoplasmic Transport Nuclear Speck Ubiquitin Protein Ligase Binding Positive Regulation Of Protein Export From Nucleus Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Glutamatergic Synapse Presynaptic Cytosol Postsynaptic Cytosol Regulation Of Protein Export From Nucleus Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Small Protein Activating Enzyme Binding PML Body Centrosome Peptidyl-serine Phosphorylation Regulation Of Intracellular Transport Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Protein Localization To Centrosome Regulation Of Intracellular Protein Transport Cellular Response To Heat Protein Sumoylation Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Ubiquitin-dependent Protein Catabolic Process RNA Processing Regulation Of Protein Localization To Centrosome RNA Binding Regulation Of Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Proteolysis Protein Localization To Organelle Dynactin Binding Positive Regulation Of Protein Catabolic Process Enzyme Binding Response To Heat Positive Regulation Of Intracellular Protein Transport Intracellular Potassium Ion Homeostasis Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Protein Localization Transcription Factor Binding SUMO Transferase Activity Membraneless Organelle Assembly Cytoskeleton Negative Regulation Of Metabolic Process Regulation Of Cellular Localization Protein Serine/threonine/tyrosine Kinase Activity Regulation Of Protein Metabolic Process Nuclear Export Negative Regulation Of Nucleobase-containing Compound Metabolic Process
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