PTAFR and GTPBP3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		PTAFR	GTPBP3
Description		platelet activating factor receptor	GTP binding protein 3, mitochondrial
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Secretory Granule Membrane Tertiary Granule Membrane	Nucleus Cytoplasm Mitochondrion Transferase Complex
	Molecular Function	Lipopolysaccharide Binding Lipopolysaccharide Immune Receptor Activity G Protein-coupled Receptor Activity Platelet Activating Factor Receptor Activity Protein Binding Phospholipid Binding G Protein-coupled Purinergic Nucleotide Receptor Activity	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity TRNA 5-taurinomethyluridine Synthase Activity
	Biological Process	Chemotaxis Inflammatory Response Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Lipopolysaccharide-mediated Signaling Pathway Response To Lipopolysaccharide Inositol Trisphosphate Biosynthetic Process G Protein-coupled Purinergic Nucleotide Receptor Signaling Pathway	TRNA Wobble Uridine Modification TRNA Modification TRNA Processing TRNA Methylation Mitochondrial TRNA Wobble Uridine Modification
Pathways		Class A/1 (Rhodopsin-like receptors) G alpha (q) signalling events Interleukin-10 signaling Neutrophil degranulation Interferon gamma signaling	tRNA modification in the mitochondrion
Drugs		Platelet Activating Factor Etizolam Rupatadine
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825)	Mitochondrial DNA copy number ( 30704525)
Interacting Genes		19 interacting genes: ARR3 ARRB2 CALM1 GORAB GRIN1 GTPBP3 IFITM3 MBP PLLP PPM1J PRNP RGS4 RHBDD2 SERINC5 SLC33A2 SPATA24 TMEM120A TMX2 TYK2	29 interacting genes: BEND7 CAPN3 CCDC32 CIC COPS5 DCAF8 DPPA4 GNE INCA1 ITGB3BP MBD3L1 MEOX2 MESD OGT PARP11 PFKL POLDIP3 PPP1R18 PRPF3 PTAFR RALY RIBC2 SERTAD3 SINHCAF TBC1D3B TBC1D3G ZFP90 ZNF69 ZNF774
Entrez ID		5724	84705
HPRD ID		01422	12255
Ensembl ID		ENSG00000169403	ENSG00000130299
Uniprot IDs		A8K7N8 P25105	B7Z563 Q969Y2
PDB IDs		5ZKP 5ZKQ 8XYD
Enriched GO Terms of Interacting Partners?		Myelin Sheath Compact Myelin G Protein-coupled Receptor Internalization Modulation Of Chemical Synaptic Transmission Regulation Of Calcium Ion Transport Regulation Of Monoatomic Cation Transmembrane Transport Structural Constituent Of Myelin Sheath Myelination Axon Ensheathment Regulation Of Monoatomic Ion Transmembrane Transport Protein Heterooligomerization Positive Regulation Of Synaptic Transmission Regulation Of Calcium Ion Transmembrane Transport Regulation Of Metal Ion Transport Positive Regulation Of Excitatory Postsynaptic Potential Response To Interferon-beta Positive Regulation Of Signal Transduction Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Substantia Nigra Development Regulation Of Monoatomic Ion Transport Terminal Bouton Propylene Metabolic Process Positive Regulation Of Metalloendopeptidase Activity Type 8 Metabotropic Glutamate Receptor Binding Response To Virus Regulation Of Membrane Potential Positive Regulation Of Receptor Signaling Pathway Via STAT Calmodulin Binding Modulation Of Excitatory Postsynaptic Potential Regulation Of Synaptic Plasticity Cellular Response To Amyloid-beta Angiotensin Receptor Binding Positive Regulation Of Cell Communication Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Excitatory Postsynaptic Potential Intracellular Signal Transduction Positive Regulation Of Signaling Negative Regulation Of High Voltage-gated Calcium Channel Activity Neural Nucleus Development Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Response To Glycine Response To Amyloid-beta Negative Regulation Of Glycine Import Across Plasma Membrane Type I Interferon-mediated Signaling Pathway Regulation Of Transcytosis TRNA 5-taurinomethyluridine Synthase Activity Mitochondrial TRNA Wobble Uridine Modification Nervous System Process Cell Surface Receptor Signaling Pathway Via JAK-STAT Regulation Of Potassium Ion Transmembrane Transport
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?