PTAFR and GORAB

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PTAFR	GORAB
Gene Name		platelet-activating factor receptor	golgin, RAB6-interacting
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus
	Molecular Function	Lipopolysaccharide Binding Lipopolysaccharide Receptor Activity G-protein Coupled Receptor Activity Platelet Activating Factor Receptor Activity Phospholipid Binding G-protein Coupled Purinergic Nucleotide Receptor Activity	Protein Binding
	Biological Process	Cytokine Production Chemotaxis Inflammatory Response Immune Response G-protein Coupled Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Lipopolysaccharide-mediated Signaling Pathway Inositol Trisphosphate Biosynthetic Process G-protein Coupled Purinergic Nucleotide Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Interferon-gamma-mediated Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events Signaling by GPCR Class A/1 (Rhodopsin-like receptors) Interferon Signaling Cytokine Signaling in Immune system Metabolic disorders of biological oxidation enzymes GPCR ligand binding Interferon gamma signaling G alpha (q) signalling events GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ARR3 ARRB1 ARRB2 CALM1 GORAB GTPBP3 RGS4 SPATA24 TYK2	12 interactors: APP BET1L FARSA HOXD9 HSD17B7 MDM2 NEDD4L NKG7 PTAFR RCHY1 SCYL1 ZNF16
Entrez ID		5724	92344
HPRD ID		01422	12144
Ensembl ID		ENSG00000169403	ENSG00000120370
Uniprot IDs		A8K7N8 P25105	B3KQ87 Q5T7V8
PDB IDs		2B0X
Enriched GO Terms of Interacting Partners?		Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway G-protein Coupled Receptor Internalization Regulation Of Protein Phosphorylation Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Receptor Internalization Detection Of Abiotic Stimulus Regulation Of Phosphorylation Platelet Activation Regulation Of Receptor Internalization Regulation Of Phosphorus Metabolic Process Negative Regulation Of Interleukin-6 Production Positive Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Cellular Protein Metabolic Process Receptor Internalization Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Protein Metabolic Process Blood Coagulation Hemostasis Receptor Metabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Calcium Ion Transport Phototransduction Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Protein Ubiquitination Regulation Of Interleukin-6 Production Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Endocytosis Detection Of Light Stimulus Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Detection Of Stimulus Regulation Of Body Fluid Levels Vesicle-mediated Transport Positive Regulation Of ERK1 And ERK2 Cascade Wound Healing Regulation Of MAPK Cascade Regulation Of Signal Transduction Notch Signaling Pathway Regulation Of Protein Binding Endocytosis Cell Activation Response To Wounding Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Protein Phosphorylation	Positive Regulation Of Cell Cycle Phase Transition Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Alcohol Metabolic Process Cellular Response To UV-C Cellular Response To Vitamin B1 Cellular Response To Sodium Dodecyl Sulfate Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER Synaptic Growth At Neuromuscular Junction Positive Regulation Of Caveolin-mediated Endocytosis Regulation Of Cell Cycle Process Cholesterol Metabolic Process Adult Locomotory Behavior Positive Regulation Of Mitotic Cell Cycle Ubiquitin-dependent Protein Catabolic Process Cellular Metabolic Process Collateral Sprouting In Absence Of Injury Modification-dependent Protein Catabolic Process RNA Metabolic Process Sterol Metabolic Process Positive Regulation Of Protein Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Phosphatidylinositol-mediated Signaling Phenylalanyl-tRNA Aminoacylation Inositol Trisphosphate Biosynthetic Process Traversing Start Control Point Of Mitotic Cell Cycle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Metabolic Process Biosynthetic Process Gene Expression Positive Regulation Of Cellular Protein Catabolic Process Protein Modification By Small Protein Conjugation Response To Vitamin B1 Response To Ether Collateral Sprouting Axon Midline Choice Point Recognition Protein Catabolic Process Adult Behavior Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
Tagcloud ?		10d a2a adenosine adora1 adora2a adora3 b4 c5ar1 calving chemoattractant deaminase holstein hydroxybutyrate leukotriene ltb4r mcal multiparous nonesterified nucleotidase p2ry2 p2y parturition peripartal pmnl purinergic sell selplg slc29a1 slc29a2
Tagcloud (Difference) ?		10d a2a adenosine adora1 adora2a adora3 b4 c5ar1 calving chemoattractant deaminase holstein hydroxybutyrate leukotriene ltb4r mcal multiparous nonesterified nucleotidase p2ry2 p2y parturition peripartal pmnl purinergic sell selplg slc29a1 slc29a2
Tagcloud (Intersection) ?