PTAFR and SLC33A2

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		PTAFR	SLC33A2
Description		platelet activating factor receptor	solute carrier family 33 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Secretory Granule Membrane Tertiary Granule Membrane	Membrane
	Molecular Function	Lipopolysaccharide Binding Lipopolysaccharide Immune Receptor Activity G Protein-coupled Receptor Activity Platelet Activating Factor Receptor Activity Protein Binding Phospholipid Binding G Protein-coupled Purinergic Nucleotide Receptor Activity	Protein Binding Transmembrane Transporter Activity
	Biological Process	Chemotaxis Inflammatory Response Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Lipopolysaccharide-mediated Signaling Pathway Response To Lipopolysaccharide Inositol Trisphosphate Biosynthetic Process G Protein-coupled Purinergic Nucleotide Receptor Signaling Pathway	Transmembrane Transport
Pathways		Class A/1 (Rhodopsin-like receptors) G alpha (q) signalling events Interleukin-10 signaling Neutrophil degranulation Interferon gamma signaling
Drugs		Platelet Activating Factor Etizolam Rupatadine
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825)
Interacting Genes		19 interacting genes: ARR3 ARRB2 CALM1 GORAB GRIN1 GTPBP3 IFITM3 MBP PLLP PPM1J PRNP RGS4 RHBDD2 SERINC5 SLC33A2 SPATA24 TMEM120A TMX2 TYK2	10 interacting genes: APPBP2 AQP6 DPAGT1 KRTAP10-6 MDFI MMGT1 PCDHGC3 PTAFR SLC7A8 UBE2J1
Entrez ID		5724	113655
HPRD ID		01422	14003
Ensembl ID		ENSG00000169403	ENSG00000167700
Uniprot IDs		A8K7N8 P25105	Q96ES6
PDB IDs		5ZKP 5ZKQ 8XYD
Enriched GO Terms of Interacting Partners?		Myelin Sheath Compact Myelin G Protein-coupled Receptor Internalization Modulation Of Chemical Synaptic Transmission Regulation Of Calcium Ion Transport Regulation Of Monoatomic Cation Transmembrane Transport Structural Constituent Of Myelin Sheath Myelination Axon Ensheathment Regulation Of Monoatomic Ion Transmembrane Transport Protein Heterooligomerization Positive Regulation Of Synaptic Transmission Regulation Of Calcium Ion Transmembrane Transport Regulation Of Metal Ion Transport Positive Regulation Of Excitatory Postsynaptic Potential Response To Interferon-beta Positive Regulation Of Signal Transduction Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Substantia Nigra Development Regulation Of Monoatomic Ion Transport Terminal Bouton Propylene Metabolic Process Positive Regulation Of Metalloendopeptidase Activity Type 8 Metabotropic Glutamate Receptor Binding Response To Virus Regulation Of Membrane Potential Positive Regulation Of Receptor Signaling Pathway Via STAT Calmodulin Binding Modulation Of Excitatory Postsynaptic Potential Regulation Of Synaptic Plasticity Cellular Response To Amyloid-beta Angiotensin Receptor Binding Positive Regulation Of Cell Communication Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Excitatory Postsynaptic Potential Intracellular Signal Transduction Positive Regulation Of Signaling Negative Regulation Of High Voltage-gated Calcium Channel Activity Neural Nucleus Development Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Response To Glycine Response To Amyloid-beta Negative Regulation Of Glycine Import Across Plasma Membrane Type I Interferon-mediated Signaling Pathway Regulation Of Transcytosis TRNA 5-taurinomethyluridine Synthase Activity Mitochondrial TRNA Wobble Uridine Modification Nervous System Process Cell Surface Receptor Signaling Pathway Via JAK-STAT Regulation Of Potassium Ion Transmembrane Transport	PH-gated Chloride Channel Activity Monoatomic Anion Channel Activity Nitrate Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transporter Activity Ammonium Transmembrane Transport Ammonium Channel Activity Nitrate Transmembrane Transport Renal Water Transport Cytoplasmic Vesicle Membrane Carbon Dioxide Transmembrane Transport UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase Activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity Glycoprotein Biosynthetic Process Protein N-linked Glycosylation Platelet Activating Factor Receptor Activity G Protein-coupled Purinergic Nucleotide Receptor Signaling Pathway Inositol Trisphosphate Biosynthetic Process G Protein-coupled Purinergic Nucleotide Receptor Activity Inositol Trisphosphate Metabolic Process Lipopolysaccharide Immune Receptor Activity L-alanine Transport Tryptophan Transport Branched-chain Amino Acid Transport Proline Transmembrane Transport Aromatic Amino Acid Transport L-alanine Transmembrane Transport L-leucine Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity L-leucine Transport L-leucine Import Across Plasma Membrane Glycine Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-alanine Import Across Plasma Membrane Thyroid Hormone Transmembrane Transporter Activity Valine Transport Negative Regulation Of Protein Exit From Endoplasmic Reticulum Hrd1p Ubiquitin Ligase Complex Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence EMC Complex Inorganic Cation Transmembrane Transporter Activity Cobalt Ion Transmembrane Transporter Activity Cobalt Ion Transport Ferrous Iron Transmembrane Transporter Activity Phosphotransferase Activity, For Other Substituted Phosphate Groups Organic Cation Transmembrane Transporter Activity Thyroid Hormone Transport
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