CYTH2 and CUX1

Number of citations of the paper that reports this interaction (PMID 12052827)
16

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		CYTH2	CUX1
Gene Name		cytohesin 2	cut-like homeobox 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Trans-Golgi Network Plasma Membrane Membrane	Nucleus Cytosol Integral Component Of Golgi Membrane
	Molecular Function	ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding Inositol 1,4,5 Trisphosphate Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding
	Biological Process	Endocytosis Vesicle-mediated Transport Actin Cytoskeleton Organization Regulation Of Cell Adhesion Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity	Negative Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Intra-Golgi Vesicle-mediated Transport Multicellular Organismal Development Lung Development Auditory Receptor Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Dendrite Morphogenesis
Pathways			Signaling by FGFR in disease Signaling by FGFR1 mutants Signaling by FGFR mutants Signaling by FGFR1 fusion mutants
Drugs
Diseases
GWAS			Response to antidepressants ( 22584459)
Protein-Protein Interactions		21 interactors: ADORA2A APC ARF1 ARF6 ARFGAP1 ARRB1 ARRB2 ATP6V0A2 CCDC120 CUX1 CYTIP DYT10 GNAQ IPCEF1 ITGB2 MAPK6 PNPLA2 PRKCA PRKCB PRKCG TRIM23	20 interactors: BIN1 CA12 CCNA1 CDC25A CDK1 CDK7 CREBBP CTSL CYTH2 EHMT2 ELAC2 GOLGA5 HMGB1 KAT2B MAX RB1 RECQL5 SATB1 SDC3 TLE4
Entrez ID		9266	1523
HPRD ID		03925	00295
Ensembl ID		ENSG00000105443	ENSG00000257923
Uniprot IDs		Q99418	P39880 Q13948 Q3LIA3
PDB IDs		1PBV 1R8M 1R8Q 1R8S 1S9D
Enriched GO Terms of Interacting Partners?		Blood Coagulation Hemostasis Platelet Activation Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Signal Transduction Apoptotic Process Programmed Cell Death Signaling Histone H3-T6 Phosphorylation Cell Death Death Cell Communication Positive Regulation Of Metabolic Process Regulation Of Receptor Internalization Cellular Response To Stimulus Regulation Of Phosphorus Metabolic Process Activation Of Phospholipase C Activity Regulation Of Protein Phosphorylation Response To Stimulus Positive Regulation Of Phospholipase C Activity Regulation Of Endocytosis Response To Stress Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phospholipase Activity Regulation Of Catalytic Activity Membrane Organization COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Regulation Of Phosphorylation Regulation Of Cellular Process Cell Surface Receptor Signaling Pathway Regulation Of Phospholipase Activity G-protein Coupled Receptor Internalization Negative Regulation Of Protein Metabolic Process Positive Regulation Of Lipase Activity Enzyme Linked Receptor Protein Signaling Pathway Golgi Vesicle Transport Protein Localization Golgi Vesicle Budding Positive Regulation Of Cellular Metabolic Process Protein Transport Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Glucose Transport Vesicle-mediated Transport Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Establishment Of Protein Localization	Regulation Of Transcription From RNA Polymerase II Promoter Organelle Organization G1/S Transition Of Mitotic Cell Cycle Chromatin Modification Negative Regulation Of Gene Expression Chromosome Organization Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cell Division Cell Cycle Process Chromatin Organization Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription From RNA Polymerase II Promoter N-terminal Peptidyl-lysine Acetylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G2/M Transition Of Mitotic Cell Cycle Viral Process Mitotic Nuclear Division Regulation Of Cell Cycle Cell Cycle Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Histone Modification Mitotic Cell Cycle Process Chromatin Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Protein Kinase Activity Negative Regulation Of RNA Biosynthetic Process Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Kinase Activity Regulation Of Nucleic Acid-templated Transcription Protein Localization To Chromosome, Centromeric Region Regulation Of RNA Biosynthetic Process N-terminal Protein Amino Acid Acetylation Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Catalytic Activity Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Apoptotic Process Regulation Of Gene Expression Programmed Cell Death Regulation Of Nitrogen Compound Metabolic Process Cell Death
Tagcloud ?			accumulated activators ancillary base burden cut ectopic excision framework haploinsufficiency homeobox implicated isoform isoforms mechanistic opposite paradoxically progression promotes protection reconcile repressors supports suppression transgenic tumorigenesis tumour whereby yet
Tagcloud (Difference) ?			accumulated activators ancillary base burden cut ectopic excision framework haploinsufficiency homeobox implicated isoform isoforms mechanistic opposite paradoxically progression promotes protection reconcile repressors supports suppression transgenic tumorigenesis tumour whereby yet
Tagcloud (Intersection) ?