CYTH2 and IPCEF1

Number of citations of the paper that reports this interaction (PMID 12920129)
16

Data Source:
BioGRID (pull down, affinity chromatography technology)
HPRD (two hybrid, in vitro, in vivo)

		CYTH2	IPCEF1
Gene Name		cytohesin 2	interaction protein for cytohesin exchange factors 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Trans-Golgi Network Plasma Membrane Membrane	Cytoplasm Plasma Membrane
	Molecular Function	ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding Inositol 1,4,5 Trisphosphate Binding	Peroxidase Activity Oxygen Transporter Activity
	Biological Process	Endocytosis Vesicle-mediated Transport Actin Cytoskeleton Organization Regulation Of Cell Adhesion Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity	Response To Oxidative Stress Oxygen Transport Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: ADORA2A APC ARF1 ARF6 ARFGAP1 ARRB1 ARRB2 ATP6V0A2 CCDC120 CUX1 CYTIP DYT10 GNAQ IPCEF1 ITGB2 MAPK6 PNPLA2 PRKCA PRKCB PRKCG TRIM23	4 interactors: CYTH1 CYTH2 CYTH3 CYTH4
Entrez ID		9266	26034
HPRD ID		03925	17851
Ensembl ID		ENSG00000105443	ENSG00000074706
Uniprot IDs		Q99418	Q8WWN9
PDB IDs		1PBV 1R8M 1R8Q 1R8S 1S9D
Enriched GO Terms of Interacting Partners?		Blood Coagulation Hemostasis Platelet Activation Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Signal Transduction Apoptotic Process Programmed Cell Death Signaling Histone H3-T6 Phosphorylation Cell Death Death Cell Communication Positive Regulation Of Metabolic Process Regulation Of Receptor Internalization Cellular Response To Stimulus Regulation Of Phosphorus Metabolic Process Activation Of Phospholipase C Activity Regulation Of Protein Phosphorylation Response To Stimulus Positive Regulation Of Phospholipase C Activity Regulation Of Endocytosis Response To Stress Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phospholipase Activity Regulation Of Catalytic Activity Membrane Organization COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Regulation Of Phosphorylation Regulation Of Cellular Process Cell Surface Receptor Signaling Pathway Regulation Of Phospholipase Activity G-protein Coupled Receptor Internalization Negative Regulation Of Protein Metabolic Process Positive Regulation Of Lipase Activity Enzyme Linked Receptor Protein Signaling Pathway Golgi Vesicle Transport Protein Localization Golgi Vesicle Budding Positive Regulation Of Cellular Metabolic Process Protein Transport Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Glucose Transport Vesicle-mediated Transport Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Establishment Of Protein Localization	Regulation Of ARF Protein Signal Transduction Regulation Of Cell Adhesion Regulation Of Ras Protein Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Establishment Of Epithelial Cell Polarity Positive Regulation Of Hydrolase Activity Positive Regulation Of Catalytic Activity Regulation Of Intracellular Signal Transduction Regulation Of Catalytic Activity Establishment Of Cell Polarity Regulation Of Signal Transduction Regulation Of Signaling Establishment Or Maintenance Of Cell Polarity Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Vesicle-mediated Transport
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