KRTAP21-2 and RNF38

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP21-2	RNF38
Description		keratin associated protein 21-2	ring finger protein 38
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Nucleus Nucleoplasm Sperm Flagellum
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process		Male Gonad Development Protein Ubiquitination
Pathways		Keratinization
Drugs
Diseases
GWAS			Bipolar disorder (inflammation and infection response interaction) ( 25781172)
Interacting Genes		30 interacting genes: ADAMTSL4 ATXN1L BEX2 CLCNKA DMRTB1 EFEMP1 FAM221A FOXD2 GATA2 KRTAP10-1 KRTAP12-2 KRTAP26-1 LCE1A LCE2A LCE5A MKRN3 NTN4 PLSCR4 POU4F2 PRR13 RNF38 RNF44 SMARCC1 SMN1 SMN2 SNRPC SPAG8 TCF7L2 VENTX ZIC1	29 interacting genes: CYSRT1 DTX3 DZIP3 KPNA4 KPRP KRTAP10-8 KRTAP11-1 KRTAP19-5 KRTAP21-2 KRTAP6-2 KRTAP7-1 KRTAP8-1 LASP1 NEDD4 OXER1 RBM11 RNF114 RNF208 RUNX1 TP53 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2H UBE2N YAP1 ZDHHC17
Entrez ID		337978	152006
HPRD ID		11215	11519
Ensembl ID		ENSG00000187026	ENSG00000137075
Uniprot IDs		Q3LI59	Q9H0F5
PDB IDs			1X4J 4V3K 4V3L 7OJX
Enriched GO Terms of Interacting Partners?		Developmental Process Sequence-specific DNA Binding SMN Complex Cajal Body Spliceosomal SnRNP Assembly Gemini Of Cajal Bodies Keratinization SMN-Sm Protein Complex DNA-templated Transcription Termination	Ubiquitin Conjugating Enzyme Activity Protein Ubiquitination Ubiquitin-protein Transferase Activity Protein Polyubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Intermediate Filament Ubiquitin Protein Ligase Activity Modification-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Protein Modification Process Proteolysis Involved In Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cardiac Muscle Tissue Regeneration Proteolysis Protein K11-linked Ubiquitination Macromolecule Catabolic Process Transferase Activity Protein Monoubiquitination Protein Metabolic Process Protein Autoubiquitination Regulation Of Cellular Response To Growth Factor Stimulus Protein K63-linked Ubiquitination Catabolic Process Proline-rich Region Binding Positive Regulation Of Protein Polyubiquitination Protein Binding Protein K6-linked Ubiquitination
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