DDX24 and SPTAN1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DDX24	SPTAN1
Gene Name		DEAD (Asp-Glu-Ala-Asp) box helicase 24	spectrin, alpha, non-erythrocytic 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Membrane	Cytosol Fascia Adherens Spectrin Microtubule Cytoskeleton Membrane Lateral Plasma Membrane Z Disc Vesicle Cuticular Plate Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	RNA Helicase Activity ATP Binding Poly(A) RNA Binding	Actin Binding Structural Constituent Of Cytoskeleton Calcium Ion Binding Protein Binding Calmodulin Binding Spectrin Binding Protein Heterodimerization Activity
	Biological Process	RNA Metabolic Process	Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Axon Guidance Actin Filament Capping
Pathways			Interaction between L1 and Ankyrins Apoptotic cleavage of cellular proteins Axon guidance Programmed Cell Death Apoptotic execution phase Nephrin interactions L1CAM interactions Caspase-mediated cleavage of cytoskeletal proteins NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS
Protein-Protein Interactions		31 interactors: BCS1L BRCA1 C9orf9 CSNK2A1 EIF3E EP300 FADD GIT1 GLRA2 HSP90AB1 HSPA5 IDO1 ITGB3BP MKS1 MRPL4 NRXN2 PAFAH1B3 PIN1 POLA2 PRF1 PTPN23 RAE1 SPTAN1 SUMO1 TERF1 TERF2 TERF2IP TMEM9B TPI1 TRDMT1 VDAC3	48 interactors: ABI1 ABL1 ACP1 ACTA1 ACTB ADD1 ANK1 CAPN1 CASP3 CASP7 CEP63 CTNNA1 DDX24 DES DISC1 EPB41 EPB41L2 EPB42 ERCC4 EVL EXOC1 FANCA FANCC GAP43 GRIA2 GRIN1 GRIN2A GRIN2B GRIN2D MAPK6 NEFL PIN4 PLEC PLEKHA5 PRKCB PTOV1 SHANK1 SHANK3 SLC9A2 SOS1 SPTB SPTBN1 SRC STAT1 SYN1 TANC1 TES TSSC4
Entrez ID		57062	6709
HPRD ID		05860	01684
Ensembl ID		ENSG00000089737	ENSG00000197694
Uniprot IDs		G3V529 Q4V9L5 Q9GZR7	Q13813
PDB IDs			2FOT 3F31 3FB2
Enriched GO Terms of Interacting Partners?		Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Chromosome Organization Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomere Maintenance RNA-dependent DNA Replication Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of Chromosome Organization Telomere Maintenance Via Telomere Shortening Protection From Non-homologous End Joining At Telomere Regulation Of Organelle Organization Telomere Capping DNA Replication Protein Localization To Chromosome, Telomeric Region Cell Cycle Regulation Of Cell Cycle Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Replicative Cell Aging Response To Stimulus Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Component Organization Cellular Response To Cytokine Stimulus Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Apoptotic Process Mitotic Cell Cycle Process Programmed Cell Death Regulation Of Protein Metabolic Process Response To Cytokine Organelle Organization Cell Cycle Process DNA Metabolic Process Cell Death Death Regulation Of Cytokine-mediated Signaling Pathway Response To External Stimulus Negative Regulation Of DNA Metabolic Process Developmental Process Regulation Of Cell Division Mitotic Cell Cycle Regulation Of Apoptotic Process Regulation Of Signal Transduction	Cell Morphogenesis Neuron Projection Morphogenesis Neuron Projection Development Cell Projection Organization Axon Development Cell Projection Morphogenesis Cell Development Cell Part Morphogenesis Cell Morphogenesis Involved In Differentiation Cell Morphogenesis Involved In Neuron Differentiation Cytoskeleton Organization Neuron Differentiation Neuron Development Axon Guidance Cell Differentiation Neurogenesis Anatomical Structure Morphogenesis Generation Of Neurons Axonogenesis Neuromuscular Process Movement Of Cell Or Subcellular Component Ionotropic Glutamate Receptor Signaling Pathway Chemotaxis Organelle Organization System Development Synaptic Transmission, Glutamatergic Response To External Stimulus Anatomical Structure Development Homeostatic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Component Organization Locomotion Glutamate Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Nervous System Development Membrane Depolarization Synaptic Transmission Neuron-neuron Synaptic Transmission Cellular Component Assembly Startle Response Actin Filament-based Process Developmental Process Regulation Of Excitatory Postsynaptic Membrane Potential Learning Multicellular Organismal Development Regulation Of Postsynaptic Membrane Potential Signaling Response To Wounding Cell Communication Cellular Response To Stimulus
Tagcloud ?		abrogation box consequent consistently dead degradation elicit helicase interacts mdm2 mediates networks nonproteolytic nucleolar polyubiquitylation pre preribosomal processing promoted proteasomal ribonucleoprotein rrna rrnp stabilization steps triggers ubiquitylation unexpected unexpectedly	adenocarcinomas atxn2 biology consistently couple deregulation dhx9 driver exome hundreds kras mutations myof never overlap preferentially ptpn13 recurrent respective rps6kb2 seq sequenced smokers somatic sp1 stratification targetable ten thousands
Tagcloud (Difference) ?		abrogation box consequent dead degradation elicit helicase interacts mdm2 mediates networks nonproteolytic nucleolar polyubiquitylation pre preribosomal processing promoted proteasomal ribonucleoprotein rrna rrnp stabilization steps triggers ubiquitylation unexpected unexpectedly	adenocarcinomas atxn2 biology couple deregulation dhx9 driver exome hundreds kras mutations myof never overlap preferentially ptpn13 recurrent respective rps6kb2 seq sequenced smokers somatic sp1 stratification targetable ten thousands
Tagcloud (Intersection) ?		consistently