PNO1 and KLF6

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PNO1	KLF6
Gene Name		partner of NOB1 homolog (S. cerevisiae)	Kruppel-like factor 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus	Nucleus Cytoplasm
	Molecular Function	Poly(A) RNA Binding	DNA Binding Metal Ion Binding
	Biological Process		Transcription, DNA-templated Cytokine-mediated Signaling Pathway B Cell Differentiation Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS			Asthma (bronchodilator response) ( 23508266)
Protein-Protein Interactions		10 interactors: ATP5C1 CSNK1E FRZB GSTP1 IGFBP5 KLF6 PDPK1 RXRG SGSM2 SUPT5H	16 interactors: APOM APP CELSR2 EHMT2 FBL GTF3C1 HDAC3 KLF4 LCOR NOP56 NUFIP1 PNO1 POLA2 SP1 TAF9 TP53
Entrez ID		56902	1316
HPRD ID		14250	03632
Ensembl ID		ENSG00000115946	ENSG00000067082
Uniprot IDs		Q9NRX1	D3GC14 Q99612
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Positive Regulation Of Metabolic Process Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Regulation Of Signal Transduction Negative Regulation Of Hepatocyte Differentiation Nitric Oxide Storage Cellular Response To Organic Substance Regulation Of Signaling Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Cellular Nitrogen Compound Metabolic Process Nitric Oxide Homeostasis Negative Regulation Of Monocyte Chemotactic Protein-1 Production Skeletal Muscle Tissue Growth Late Endosome To Golgi Transport Skeletal Muscle Tissue Development Common Myeloid Progenitor Cell Proliferation Negative Regulation Of Nitric-oxide Synthase Biosynthetic Process Skeletal Muscle Organ Development Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Cell Proliferation Convergent Extension Involved In Organogenesis Mammary Gland Involution Negative Regulation Of Wnt Signaling Pathway System Development Negative Regulation Of Protein Kinase Activity Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Superoxide Anion Generation Negative Regulation Of Cellular Protein Metabolic Process Tissue Development Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Kinase Activity Response To Stimulus Regulation Of Intracellular Signal Transduction Organ Development Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Nucleobase-containing Compound Metabolic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of JUN Kinase Activity Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Striated Muscle Cell Apoptotic Process Type B Pancreatic Cell Proliferation Wnt Signaling Pathway Muscle Organ Development Regulation Of Cellular Component Organization Regulation Of Superoxide Anion Generation	Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Chromosome Organization Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Fluid Shear Stress Chromatin Organization Gene Expression Regulation Of RNA Metabolic Process Regulation Of DNA Replication Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Component Assembly RRNA Transcription Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Notch Signaling Pathway Protein Import Into Nucleus, Translocation Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Histone H3-K9 Modification Transcription, DNA-templated Response To Fluid Shear Stress RNA Biosynthetic Process Regulation Of Signal Transduction By P53 Class Mediator Cellular Response To Growth Factor Stimulus Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Response To Growth Factor Chromatin Modification Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Growth Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Neuron Apoptotic Process Negative Regulation Of Signaling Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process
Tagcloud ?			allowed anchorage arrest challenged constitutive conversion decreasing driven ectopic foci g12v highlighting hindering impaired jnk jun knockdown kruppel nih3t3 oncogenic p21 physiology ras relevance spontaneous stably transformed tumorigenesis tumorigenic
Tagcloud (Difference) ?			allowed anchorage arrest challenged constitutive conversion decreasing driven ectopic foci g12v highlighting hindering impaired jnk jun knockdown kruppel nih3t3 oncogenic p21 physiology ras relevance spontaneous stably transformed tumorigenesis tumorigenic
Tagcloud (Intersection) ?