PNO1 and RXRG

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PNO1	RXRG
Gene Name		partner of NOB1 homolog (S. cerevisiae)	retinoid X receptor, gamma
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus	Nucleoplasm
	Molecular Function	Poly(A) RNA Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Steroid Hormone Receptor Activity 9-cis Retinoic Acid Receptor Activity Protein Binding Zinc Ion Binding
	Biological Process		Transcription Initiation From RNA Polymerase II Promoter Peripheral Nervous System Development Heart Development Skeletal Muscle Tissue Development Gene Expression Neuron Differentiation Regulation Of Myelination Response To Retinoic Acid Steroid Hormone Mediated Signaling Pathway Retinoic Acid Receptor Signaling Pathway Protein Homotetramerization Transmembrane Transport Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus
Pathways			Generic Transcription Pathway Signaling by Retinoic Acid Nuclear Receptor transcription pathway Orphan transporters
Drugs			Adapalene Bexarotene Acitretin Alitretinoin Tretinoin Etretinate
Diseases
GWAS			AIDS ( 19754311) Menarche (age at onset) ( 21102462) Personality dimensions ( 21368711)
Protein-Protein Interactions		10 interactors: ATP5C1 CSNK1E FRZB GSTP1 IGFBP5 KLF6 PDPK1 RXRG SGSM2 SUPT5H	29 interactors: CAMK2B CEBPZ CHGB CREBBP DCK HOXD4 ITGB3BP LRSAM1 MAP4 MPPED2 NCOA6 NCOR2 NR0B2 NR1H2 NR1H3 NR1H4 NR1I2 NR4A1 PNO1 PPARA PPARD PPARG RARA RARB RARG SRF THRA THRB VDR
Entrez ID		56902	6258
HPRD ID		14250	01579
Ensembl ID		ENSG00000115946	ENSG00000143171
Uniprot IDs		Q9NRX1	F1D8Q7 F1T097 P48443
PDB IDs			2GL8
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Positive Regulation Of Metabolic Process Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Regulation Of Signal Transduction Negative Regulation Of Hepatocyte Differentiation Nitric Oxide Storage Cellular Response To Organic Substance Regulation Of Signaling Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Cellular Nitrogen Compound Metabolic Process Nitric Oxide Homeostasis Negative Regulation Of Monocyte Chemotactic Protein-1 Production Skeletal Muscle Tissue Growth Late Endosome To Golgi Transport Skeletal Muscle Tissue Development Common Myeloid Progenitor Cell Proliferation Negative Regulation Of Nitric-oxide Synthase Biosynthetic Process Skeletal Muscle Organ Development Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Cell Proliferation Convergent Extension Involved In Organogenesis Mammary Gland Involution Negative Regulation Of Wnt Signaling Pathway System Development Negative Regulation Of Protein Kinase Activity Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Superoxide Anion Generation Negative Regulation Of Cellular Protein Metabolic Process Tissue Development Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Kinase Activity Response To Stimulus Regulation Of Intracellular Signal Transduction Organ Development Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Nucleobase-containing Compound Metabolic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of JUN Kinase Activity Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Striated Muscle Cell Apoptotic Process Type B Pancreatic Cell Proliferation Wnt Signaling Pathway Muscle Organ Development Regulation Of Cellular Component Organization Regulation Of Superoxide Anion Generation	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Cellular Response To Steroid Hormone Stimulus Intracellular Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Response To Steroid Hormone Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Response To Hormone Transcription, DNA-templated RNA Biosynthetic Process Cellular Response To Hormone Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Response To Lipid Positive Regulation Of Transcription, DNA-templated Response To Organic Cyclic Compound Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Organic Substance Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To Organic Substance Gene Expression Cellular Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Cholesterol Storage Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process
Tagcloud ?			band bands chromosome chromosomes cosmid cosmids cytogenetic encoded establishing heterodimeric location loci pairwise partners proximity q22 q23 q34 reference respond retinoic retinoid rxra rxrb rxrs separate tr vdr
Tagcloud (Difference) ?			band bands chromosome chromosomes cosmid cosmids cytogenetic encoded establishing heterodimeric location loci pairwise partners proximity q22 q23 q34 reference respond retinoic retinoid rxra rxrb rxrs separate tr vdr
Tagcloud (Intersection) ?