Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
PNO1 and IGFBP5
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
PNO1
IGFBP5
Gene Name
partner of NOB1 homolog (S. cerevisiae)
insulin-like growth factor binding protein 5
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleolus
Extracellular Region
Extracellular Space
Insulin-like Growth Factor Binding Protein Complex
Molecular Function
Poly(A) RNA Binding
Fibronectin Binding
Protein Binding
Insulin-like Growth Factor I Binding
Insulin-like Growth Factor II Binding
Biological Process
Regulation Of Cell Growth
Osteoblast Differentiation
Glucose Metabolic Process
Signal Transduction
Regulation Of Glucose Metabolic Process
Negative Regulation Of Smooth Muscle Cell Migration
Negative Regulation Of Translation
Negative Regulation Of Cell Migration
Hair Follicle Morphogenesis
Intracellular Signal Transduction
Glucose Homeostasis
Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Cellular Protein Metabolic Process
Type B Pancreatic Cell Proliferation
Negative Regulation Of Osteoblast Differentiation
Skeletal Muscle Tissue Growth
Negative Regulation Of Smooth Muscle Cell Proliferation
Striated Muscle Cell Differentiation
Positive Regulation Of Protein Kinase B Signaling
Mammary Gland Involution
Cellular Response To CAMP
Cellular Response To Organic Cyclic Compound
Pathways
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Drugs
Diseases
GWAS
Thyroid hormone levels (
23408906
)
Visceral fat (
22589738
)
Protein-Protein Interactions
10 interactors:
ATP5C1
CSNK1E
FRZB
GSTP1
IGFBP5
KLF6
PDPK1
RXRG
SGSM2
SUPT5H
17 interactors:
ADAM12
BAG6
F2
FHL2
FN1
IGF1
IGF2
IGFALS
KPNB1
PAPPA2
PNO1
RASSF1
SERPINE1
SPP1
TF
THBS1
VTN
Entrez ID
56902
3488
HPRD ID
14250
00901
Ensembl ID
ENSG00000115946
ENSG00000115461
Uniprot IDs
Q9NRX1
P24593
PDB IDs
1BOE
1H59
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Signal Transduction
Negative Regulation Of Signaling
Positive Regulation Of Metabolic Process
Response To Organic Substance
Positive Regulation Of Cellular Metabolic Process
Regulation Of Signal Transduction
Negative Regulation Of Hepatocyte Differentiation
Nitric Oxide Storage
Cellular Response To Organic Substance
Regulation Of Signaling
Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Cellular Nitrogen Compound Metabolic Process
Nitric Oxide Homeostasis
Negative Regulation Of Monocyte Chemotactic Protein-1 Production
Skeletal Muscle Tissue Growth
Late Endosome To Golgi Transport
Skeletal Muscle Tissue Development
Common Myeloid Progenitor Cell Proliferation
Negative Regulation Of Nitric-oxide Synthase Biosynthetic Process
Skeletal Muscle Organ Development
Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of Cell Proliferation
Convergent Extension Involved In Organogenesis
Mammary Gland Involution
Negative Regulation Of Wnt Signaling Pathway
System Development
Negative Regulation Of Protein Kinase Activity
Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Superoxide Anion Generation
Negative Regulation Of Cellular Protein Metabolic Process
Tissue Development
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Kinase Activity
Response To Stimulus
Regulation Of Intracellular Signal Transduction
Organ Development
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of JUN Kinase Activity
Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Negative Regulation Of Striated Muscle Cell Apoptotic Process
Type B Pancreatic Cell Proliferation
Wnt Signaling Pathway
Muscle Organ Development
Regulation Of Cellular Component Organization
Regulation Of Superoxide Anion Generation
Platelet Degranulation
Platelet Activation
Blood Coagulation
Hemostasis
Positive Regulation Of Wound Healing
Negative Regulation Of Fibrinolysis
Regulation Of Body Fluid Levels
Exocytosis
Wound Healing
Regulation Of Fibrinolysis
Cell Activation
Response To Wounding
Regulation Of Blood Coagulation
Secretion By Cell
Regulation Of Cellular Component Organization
Regulation Of Cellular Protein Metabolic Process
Response To Stress
Positive Regulation Of Blood Coagulation
Response To Stimulus
Regulation Of Wound Healing
Regulation Of Cell Adhesion
Secretion
Positive Regulation Of Coagulation
Negative Regulation Of Proteolysis
Regulation Of Protein Metabolic Process
Regulation Of Proteolysis
Regulation Of Smooth Muscle Cell Migration
Negative Regulation Of Protein Processing
Extracellular Matrix Organization
Extracellular Structure Organization
Positive Regulation Of Cell Adhesion
Positive Regulation Of Cellular Protein Metabolic Process
Anatomical Structure Development
Regulation Of Protein Processing
Negative Regulation Of Blood Coagulation
Anatomical Structure Morphogenesis
Positive Regulation Of Protein Metabolic Process
Regulation Of Cell-substrate Adhesion
Negative Regulation Of Coagulation
Negative Regulation Of Plasminogen Activation
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Wound Healing
Cell Differentiation
Striated Muscle Cell Differentiation
Developmental Process
Exocrine Pancreas Development
Positive Regulation Of Protein Modification Process
Positive Regulation Of Protein Kinase B Signaling
Vesicle-mediated Transport
Ossification
Tagcloud
?
4h
antisense
autocrine
benzopyran
c2
igfr
igfs
indirectly
ly294002
messenger
modulated
morpholinyl
myoblast
myoblasts
p70
p70s6k
persisted
phenyl
phosphatidylinositol
pi3
prevents
proliferating
quiescent
rapamycin
s6
stably
wortmaninn
Tagcloud (Difference)
?
4h
antisense
autocrine
benzopyran
c2
igfr
igfs
indirectly
ly294002
messenger
modulated
morpholinyl
myoblast
myoblasts
p70
p70s6k
persisted
phenyl
phosphatidylinositol
pi3
prevents
proliferating
quiescent
rapamycin
s6
stably
wortmaninn
Tagcloud (Intersection)
?