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PNO1 and FRZB
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
PNO1
FRZB
Gene Name
partner of NOB1 homolog (S. cerevisiae)
frizzled-related protein
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleolus
Extracellular Space
Membrane
Integral Component Of Membrane
Molecular Function
Poly(A) RNA Binding
G-protein Coupled Receptor Activity
Wnt-protein Binding
Wnt-activated Receptor Activity
Biological Process
Skeletal System Development
Negative Regulation Of Cell Proliferation
Negative Regulation Of Cell Development
Neural Crest Cell Differentiation
Negative Regulation Of Wnt Signaling Pathway
Negative Regulation Of Cell Growth
Non-canonical Wnt Signaling Pathway
Positive Regulation Of Apoptotic Process
Positive Regulation Of Fat Cell Differentiation
Convergent Extension Involved In Organogenesis
Negative Regulation Of Cartilage Development
Somite Development
Negative Regulation Of Hepatocyte Differentiation
Negative Regulation Of Canonical Wnt Signaling Pathway
Cochlea Morphogenesis
Pathways
Drugs
Diseases
GWAS
Waist-to-hip circumference ratio (interaction) (
23192594
)
Protein-Protein Interactions
10 interactors:
ATP5C1
CSNK1E
FRZB
GSTP1
IGFBP5
KLF6
PDPK1
RXRG
SGSM2
SUPT5H
7 interactors:
BBS10
EHF
ELF5
PNO1
POLA2
RBX1
SMAD1
Entrez ID
56902
2487
HPRD ID
14250
07282
Ensembl ID
ENSG00000115946
ENSG00000162998
Uniprot IDs
Q9NRX1
D9ZGF6
Q92765
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Signal Transduction
Negative Regulation Of Signaling
Positive Regulation Of Metabolic Process
Response To Organic Substance
Positive Regulation Of Cellular Metabolic Process
Regulation Of Signal Transduction
Negative Regulation Of Hepatocyte Differentiation
Nitric Oxide Storage
Cellular Response To Organic Substance
Regulation Of Signaling
Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Cellular Nitrogen Compound Metabolic Process
Nitric Oxide Homeostasis
Negative Regulation Of Monocyte Chemotactic Protein-1 Production
Skeletal Muscle Tissue Growth
Late Endosome To Golgi Transport
Skeletal Muscle Tissue Development
Common Myeloid Progenitor Cell Proliferation
Negative Regulation Of Nitric-oxide Synthase Biosynthetic Process
Skeletal Muscle Organ Development
Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of Cell Proliferation
Convergent Extension Involved In Organogenesis
Mammary Gland Involution
Negative Regulation Of Wnt Signaling Pathway
System Development
Negative Regulation Of Protein Kinase Activity
Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Superoxide Anion Generation
Negative Regulation Of Cellular Protein Metabolic Process
Tissue Development
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Kinase Activity
Response To Stimulus
Regulation Of Intracellular Signal Transduction
Organ Development
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of JUN Kinase Activity
Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Negative Regulation Of Striated Muscle Cell Apoptotic Process
Type B Pancreatic Cell Proliferation
Wnt Signaling Pathway
Muscle Organ Development
Regulation Of Cellular Component Organization
Regulation Of Superoxide Anion Generation
Regulation Of Transcription From RNA Polymerase II Promoter
Cell Proliferation
Transcription From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Primary MiRNA Processing
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Heterocycle Metabolic Process
Epithelium Development
Cellular Aromatic Compound Metabolic Process
Osteoblast Fate Commitment
Cellular Nitrogen Compound Metabolic Process
Protein Neddylation
SMAD Protein Complex Assembly
Cellular Protein Complex Assembly
Positive Regulation Of Transcription, DNA-templated
Nitrogen Compound Metabolic Process
Homeostatic Process
Chaperone-mediated Protein Complex Assembly
Mesodermal Cell Fate Commitment
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Cardiac Muscle Cell Proliferation
Telomere Maintenance Via Semi-conservative Replication
Positive Regulation Of Cellular Biosynthetic Process
Production Of MiRNAs Involved In Gene Silencing By MiRNA
Cellular Response To BMP Stimulus
Mammary Gland Epithelial Cell Differentiation
Nuclear DNA Replication
Telomere Maintenance Via Recombination
Cellular Macromolecule Biosynthetic Process
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Ectoderm Development
Tissue Development
Nonmotile Primary Cilium Assembly
Mesodermal Cell Differentiation
Macromolecule Biosynthetic Process
Epithelial Cell Differentiation
Mitotic Recombination
DNA Strand Elongation Involved In DNA Replication
Cell Fate Commitment Involved In Formation Of Primary Germ Layer
Protein Import Into Nucleus, Translocation
DNA Strand Elongation
Cardiac Muscle Tissue Growth
Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Muscle Cell Apoptotic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus
Photoreceptor Cell Maintenance
DNA Replication Initiation
Tagcloud
?
abcb1b
administrated
brosis
colla1
corroborated
dkk1
dkk2
dkk3
dkk4
fi
frizzled
fz1
fz5
fz7
nano
nephrotoxicity
osteopontin
sfrp
tio2
wnt1
wnt10a
wnt11
wnt2
wnt3
wnt4
wnt5a
wnt6
wnt7a
wnt9a
Tagcloud (Difference)
?
abcb1b
administrated
brosis
colla1
corroborated
dkk1
dkk2
dkk3
dkk4
fi
frizzled
fz1
fz5
fz7
nano
nephrotoxicity
osteopontin
sfrp
tio2
wnt1
wnt10a
wnt11
wnt2
wnt3
wnt4
wnt5a
wnt6
wnt7a
wnt9a
Tagcloud (Intersection)
?