C10orf2 and AKTIP

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		C10orf2	AKTIP
Gene Name		chromosome 10 open reading frame 2	AKT interacting protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix Mitochondrial Nucleoid	Nucleolus Cytoplasm Golgi Apparatus Plasma Membrane HOPS Complex FHF Complex
	Molecular Function	Protease Binding Single-stranded DNA Binding ATP Binding 5'-3' DNA Helicase Activity	Protein Binding Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Mitochondrial DNA Replication DNA Unwinding Involved In DNA Replication Transcription From Mitochondrial Promoter Organelle Organization Mitochondrion Organization Protein Hexamerization Protein Homooligomerization	Positive Regulation Of Protein Phosphorylation Apoptotic Process Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Protein Ubiquitination Positive Regulation Of Protein Binding Early Endosome To Late Endosome Transport
Pathways		Organelle biogenesis and maintenance Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: AKTIP SMAD9	23 interactors: AKT1 ASS1 C10orf2 CTBP2 DZIP3 EXOC7 FAM160A2 GTF3C1 HOOK1 HOOK2 HOOK3 IMMT KIAA1377 MARCH5 PDPK1 POLA2 RPA1 TRIM23 TRIM41 UTP14A VPS16 VPS18 VPS41
Entrez ID		56652	64400
HPRD ID		05830	07467
Ensembl ID		ENSG00000107815	ENSG00000166971
Uniprot IDs		E5KSY5 Q96RR1 Q9H6V3	Q9H8T0
PDB IDs
Enriched GO Terms of Interacting Partners?			Endosome Organization Vacuole Organization Lysosome Organization Early Endosome To Late Endosome Transport Vacuolar Transport Endosome To Lysosome Transport Regulation Of SNARE Complex Assembly Lysosomal Transport Protein Transport Establishment Of Protein Localization Protein Localization Organelle Organization Endosomal Transport Endomembrane System Organization Cytoplasmic Transport Cellular Localization Intracellular Transport Establishment Of Localization In Cell Regulation Of Vesicle Fusion Protein Localization To Organelle DNA-dependent DNA Replication Telomere Maintenance Via Semi-conservative Replication Protein Ubiquitination Cellular Protein Localization Nuclear DNA Replication Telomere Maintenance Via Recombination Protein Modification By Small Protein Conjugation Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Cellular Response To Epidermal Growth Factor Stimulus Vesicle-mediated Transport Positive Regulation Of Protein Localization To Plasma Membrane Response To Epidermal Growth Factor Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Protein Import Into Nucleus, Translocation Regulation Of Vesicle-mediated Transport DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening G1/S Transition Of Mitotic Cell Cycle Response To Fluid Shear Stress Cytoplasmic Microtubule Organization Viral Entry Into Host Cell Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Temperature Stimulus Viral Life Cycle Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Entry Into Host Cell Argininosuccinate Metabolic Process Regulation Of Vacuole Fusion, Non-autophagic
Tagcloud ?		autosomal cofactor controversial dguok dysmotility efficacious encephalomyopathic encephalopathy hepatocerebral heterogeneous hypotonia infancy mngie mpv17 mtdna myopathic neurogastrointestinal neurological neuropathy phenotypically polg recessive rrm2b sucla2 suclg1 tk2 tymp typically weakness	apoa1bp apolipoprotein behaves biophysical cathepsin cellulo characterisation ctsb differently forkhead foxe3 implication initiating milieu modules mrnas naturally neighbouring pg4 qrt quadruplex quadruplexes recognises render scans though untranslated utr works
Tagcloud (Difference) ?		autosomal cofactor controversial dguok dysmotility efficacious encephalomyopathic encephalopathy hepatocerebral heterogeneous hypotonia infancy mngie mpv17 mtdna myopathic neurogastrointestinal neurological neuropathy phenotypically polg recessive rrm2b sucla2 suclg1 tk2 tymp typically weakness	apoa1bp apolipoprotein behaves biophysical cathepsin cellulo characterisation ctsb differently forkhead foxe3 implication initiating milieu modules mrnas naturally neighbouring pg4 qrt quadruplex quadruplexes recognises render scans though untranslated utr works
Tagcloud (Intersection) ?