EIF4ENIF1 and DDX6

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EIF4ENIF1	DDX6
Gene Name		eukaryotic translation initiation factor 4E nuclear import factor 1	DEAD (Asp-Glu-Ala-Asp) box helicase 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane PML Body Nuclear Speck Intracellular Membrane-bounded Organelle	Cytoplasmic MRNA Processing Body Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane RISC Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Protein Transporter Activity Poly(A) RNA Binding	RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Protein Domain Specific Binding Poly(A) RNA Binding
	Biological Process	Protein Transport	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Gene Expression Cytoplasmic MRNA Processing Body Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways			mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS			Celiac disease and Rheumatoid arthritis ( 21383967) Vitiligo ( 22951725)
Protein-Protein Interactions		19 interactors: ATXN1 CDK6 DDX6 DEF6 DTX2 EFHC1 EIF3E EIF4E EIF4E2 FANCL FDPS HNRNPF KRT19 MGAT5B OIP5 SMAD3 SPAG5 TTC19 TXLNA	24 interactors: AES BEND7 BIRC7 CALCOCO2 CEP70 EDC3 EIF4ENIF1 GOLGA2 IKZF1 KRT40 KRTAP10-3 KRTAP10-8 NONO PNMA5 RUNDC3A SDCCAG3 SRPK2 TCF4 TRIM27 TRIM37 U2AF2 VPS52 ZBTB8A ZNF24
Entrez ID		56478	1656
HPRD ID		10456	02638
Ensembl ID		ENSG00000184708
Uniprot IDs		Q9NRA8	B2R858 P26196
PDB IDs			1VEC 2WAX 2WAY
Enriched GO Terms of Interacting Partners?		Cellular Macromolecular Complex Assembly Cell Cycle Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Cell Division RNA Catabolic Process Posttranscriptional Regulation Of Gene Expression Cell Cycle Negative Regulation Of Osteoblast Differentiation Translational Initiation MRNA Metabolic Process Positive Regulation Of Cell-matrix Adhesion Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Viral Process Cell Dedifferentiation Positive Regulation Of Transforming Growth Factor Beta3 Production RNA Processing Regulation Of Translation Geranyl Diphosphate Biosynthetic Process Farnesyl Diphosphate Biosynthetic Process Negative Regulation Of Ossification Mitotic Cell Cycle Process Negative Regulation Of Translation Evasion Or Tolerance Of Host Defenses By Virus Mitotic Cell Cycle Cellular Component Assembly Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Farnesyl Diphosphate Metabolic Process Regulation Of Cell-matrix Adhesion Lymphocyte Activation Positive Regulation Of Cell-substrate Adhesion Regulation Of Extracellular Matrix Assembly Nuclear Export	Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Protein Binding Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Embryonic Digestive Tract Development Regulation Of Nitrogen Compound Metabolic Process MRNA Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Neutrophil Differentiation Nuclear Speck Organization Regulation Of Natural Killer Cell Apoptotic Process Negative Regulation Of Protein Binding Regulation Of Cell Death Regulation Of Binding Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cell Death Nucleobase-containing Compound Metabolic Process Negative Regulation Of Interleukin-2 Secretion Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Embryonic Ectodermal Digestive Tract Development Negative Regulation Of Viral Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Histone H2A-K119 Monoubiquitination Regulation Of MRNA Processing RNA Splicing Regulation Of Gene Expression Negative Regulation Of Binding Regulation Of RNA Splicing Maintenance Of DNA Repeat Elements Positive Regulation Of Anoikis Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Ectodermal Cell Differentiation Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Tagcloud ?			concerted contain continuum cpeb dendritic dormant engaged fmrp foci fus granules hud masked messengers mrnas polysomes pumilio rbps repressed smaug stalled staufen synapse thousands tls transcriptome translational trapped zbp1
Tagcloud (Difference) ?			concerted contain continuum cpeb dendritic dormant engaged fmrp foci fus granules hud masked messengers mrnas polysomes pumilio rbps repressed smaug stalled staufen synapse thousands tls transcriptome translational trapped zbp1
Tagcloud (Intersection) ?