BRAF and RAF1

  • Number of citations of the paper that reports this interaction (PMID 11325826)
  • 43
  • Data Source:
  • HPRD (in vivo)

BRAF

RAF1

Gene Name B-Raf proto-oncogene, serine/threonine kinase Raf-1 proto-oncogene, serine/threonine kinase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Response to Vitamin E supplementation ( 22437554)
Protein-Protein Interactions 25 interactors: AKT1 BAD CCDC88A HRAS MAP2K1 MAP2K2 MAPK1 MRAS NEDD4L OIP5 PAK2 PRKACA PRKCE RAF1 RAP1A RAP1GAP RHEB RPS6KB2 SGK1 TERF1 YWHAB YWHAG YWHAH YWHAQ YWHAZ 123 interactors: ADCY6 AGTR1 AKT1 AR ARRB2 BAD BAG1 BCL2 BCL2L1 BCL6 BIRC2 BIRC3 BRAF CCT3 CDC25A CFLAR CNKSR1 COPS3 COPS7A CPS1 DCAF8 DMPK EFEMP1 ERBB2IP FYCO1 FYN GNB2 GNG4 GRB10 HRAS HSP90AA1 HSPA4 HSPA8 IL2RB INSR INTS10 JAK1 JAK2 KRAS KRT18 KRT8 KSR1 KSR2 LCK LRPAP1 MAP2K1 MAP2K2 MAP3K1 MAP3K5 MAPK1 MAPK3 MAPK7 MAPK8 MAPK8IP3 MRAS MYBPC1 MYC NEDD4 NPLOC4 NR3C1 NRAS NUDT14 OIP5 PACSIN3 PAK1 PAK2 PAK3 PBK PDGFRB PEBP1 PEBP4 PEX5L PHB PHKA2 PIN1 PKM PPP1CC PPP2CB PRKAA1 PRKACA PRKAR1A PRKCA PRKCD PRKCE PRKCZ PRKG1 PRPF6 PURA RANBP9 RAP1A RAP2A RASD2 RB1 RBBP8 RBL2 RFXANK RHEB RRAS RRAS2 RSU1 SHOC2 SPRY2 SPRY4 SRC STK26 STK3 STUB1 TBXA2R TIMM50 TMEM70 TSC22D3 UBC UBE2D2 VAV1 VDAC1 XIAP YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ YY1
Entrez ID 673 5894
HPRD ID 01264 01265
Ensembl ID ENSG00000157764 ENSG00000132155
Uniprot IDs P15056 B4E0X2 L7RRS6 P04049
PDB IDs 1UWH 1UWJ 2FB8 2L05 3C4C 3D4Q 3IDP 3II5 3NY5 3OG7 3PPJ 3PPK 3PRF 3PRI 3PSB 3PSD 3Q4C 3Q96 3SKC 3TV4 3TV6 4DBN 4E26 4E4X 4EHE 4EHG 4FK3 4G9C 4G9R 4H58 4JVG 4KSP 4KSQ 4MBJ 1C1Y 1FAQ 1FAR 1GUA 1RFA 3CU8 3IQJ 3IQU 3IQV 3KUC 3KUD 3NKX 3O8I 3OMV 4FJ3 4G0N 4G3X 4IEA 4IHL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
al  araf  augmentation  craf1  die  differentiated  disruption  dramatically  drosophila  elegans  embryos  enlarged  establish  failed  finding  gestation  interacts  mek  membranes  mid  mutagenesis  programmed  ras  signalling  unlike  unpublished  vessels  w 
cot  densitometry  erk2  hog  immunoreactivities  jnks  kinases  mapkapk2  mapks  mek1  mekkl  mkk3  mlk3  mos  myocytes  pak2  pakl  phenomena  probed  proliferate  proto  rafb  resist  rsk1  rsk2  sekl  tpl  ventricle  ventricles 
Tagcloud (Difference) ?
al  araf  augmentation  craf1  die  differentiated  disruption  dramatically  drosophila  elegans  embryos  enlarged  establish  failed  finding  gestation  interacts  mek  membranes  mid  mutagenesis  programmed  ras  signalling  unlike  unpublished  vessels  w 
cot  densitometry  erk2  hog  immunoreactivities  jnks  kinases  mapkapk2  mapks  mek1  mekkl  mkk3  mlk3  mos  myocytes  pak2  pakl  phenomena  probed  proliferate  proto  rafb  resist  rsk1  rsk2  sekl  tpl  ventricle  ventricles 
Tagcloud (Intersection) ?