DMAP1 and ING1

Number of citations of the paper that reports this interaction (PubMedID 14665632)
0

Data Source:
HPRD (in vitro, in vivo)

		DMAP1	ING1
Description		DNA methyltransferase 1 associated protein 1	inhibitor of growth family member 1
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GO Annotations	Cellular Component	Nucleosome Swr1 Complex Nucleus Nucleoplasm Replication Fork Chromosome Cytoplasm Cytosol NuA4 Histone Acetyltransferase Complex	Nucleus Sin3-type Complex
	Molecular Function	Transcription Corepressor Activity Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Protein Binding Zinc Ion Binding Metal Ion Binding Histone H3K4me3 Reader Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Repair Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Positive Regulation Of Protein Import Into Nucleus Regulation Of Apoptotic Process Response To Ethanol Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Protein Import Into Nucleus Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Programmed Cell Death Positive Regulation Of DNA-templated Transcription Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Blood protein levels ( 30072576) Erosive tooth wear (severe vs non-severe) ( 29898447)
Interacting Genes		41 interacting genes: ARFIP2 BFSP2 BTG3 C1orf216 CCHCR1 CDCA7L CEBPB DAXX DNMT1 DRC4 EXOC8 GINS4 HDAC2 HSF2BP HSPB1 ING1 KRT75 LMNB1 LRSAM1 MIS18A MNAT1 MORF4L1 MRGBP NAP1L2 OGT PFDN1 PIBF1 RGS6 SAAL1 SBK3 SUOX TCEANC TCHP TLK2 TOMM34 TRIM21 TSG101 TSGA10IP TXLNA TXLNB URI1	29 interacting genes: BRMS1 BRMS1L COPS2 CYTOR DMAP1 EP300 ESR1 EXOC4 H3C14 HDAC1 HDAC2 KAT2B MRGBP NQO1 PCNA RBBP4 RBBP7 RBP1 SAP30 SFN SIN3A TP53 UBC YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Entrez ID		55929	3621
HPRD ID		05465	03337
Ensembl ID		ENSG00000178028	ENSG00000153487
Uniprot IDs		Q9NPF5	A0A0C4DFW2 Q9UK53
PDB IDs		3HM5 4IEJ 8QR1 8X15 8X19 8X1C 8XVG 8XVT 9C57 9C62 9C6N	2QIC
Enriched GO Terms of Interacting Partners?		Sin3-type Complex Chromatin Organization Negative Regulation Of Stem Cell Population Maintenance	Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Stem Cell Population Maintenance Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Stem Cell Population Maintenance Negative Regulation Of Biosynthetic Process Histone Deacetylase Binding Negative Regulation Of Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Transcription By RNA Polymerase II Histone Deacetylase Complex Phosphoserine Residue Binding Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of RNA Metabolic Process Chromatin Organization Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Chromatin Remodeling Nucleus Rhythmic Process Regulation Of Gene Expression Protein Sequestering Activity NuRD Complex Regulation Of Cell Fate Commitment Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Signal Transduction Regulation Of Metabolic Process Protein-containing Complex Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Cell Migration Cellular Response To Stress Chromatin Binding Regulation Of Cell Fate Specification Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Nucleoplasm Enzyme Binding
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