DMAP1 and TOMM34

Number of citations of the paper that reports this interaction (PMID 11913976)
5

Data Source:
BioGRID (two hybrid)
HPRD (in vitro, two hybrid)

		DMAP1	TOMM34
Gene Name		DNA methyltransferase 1 associated protein 1	translocase of outer mitochondrial membrane 34
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Replication Fork Cytoplasm NuA4 Histone Acetyltransferase Complex	Nucleus Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Chromatin Binding Transcription Corepressor Activity Protein Binding	Heat Shock Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Repair DNA Methylation Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Regulation Of Growth Positive Regulation Of Transcription Factor Import Into Nucleus Histone H4 Acetylation Histone H2A Acetylation Negative Regulation Of Transcription, DNA-templated	Protein Targeting To Mitochondrion
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: DAXX DNMT1 HDAC2 ING1 MNAT1 MRGBP RGS6 TOMM34 TSG101 URI1	10 interactors: ACD ATP6V1D DMAP1 HSP90AA1 POT1 PRKAA1 RAB11FIP3 TERF1 TINF2 VCP
Entrez ID		55929	10953
HPRD ID		05465	11641
Ensembl ID		ENSG00000178028	ENSG00000025772
Uniprot IDs		B4DQG8 Q9NPF5	Q15785
PDB IDs		3HM5 4IEJ
Enriched GO Terms of Interacting Partners?		Chromatin Modification Regulation Of Growth Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression Chromatin Organization Chromosome Organization Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Organelle Organization Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Cell Proliferation Regulation Of Cell Death Regulation Of Metabolic Process Regulation Of Cell Growth Regulation Of Cellular Component Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway RNA Metabolic Process Gene Silencing Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Maintenance Of Chromatin Silencing Viral Process Epidermal Cell Differentiation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cell Cycle C-5 Methylation Of Cytosine Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Cellular Metabolic Process Regulation Of Extracellular Vesicular Exosome Assembly Maintenance Of DNA Methylation Negative Regulation Of MHC Class II Biosynthetic Process Chromatin Remodeling Positive Regulation Of Gene Expression Fungiform Papilla Formation Negative Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Transcription From RNA Polymerase II Promoter	Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Assembly Negative Regulation Of DNA Replication Telomere Maintenance Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Cellular Component Assembly Organelle Organization Regulation Of DNA Replication Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Biosynthetic Process Chromosome Organization Regulation Of Chromosome Organization DNA Metabolic Process Protein Localization To Chromosome, Telomeric Region Telomere Capping Positive Regulation Of Telomerase Activity Negative Regulation Of Biosynthetic Process Homeostatic Process Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Positive Regulation Of DNA Metabolic Process Positive Regulation Of DNA Biosynthetic Process RNA-dependent DNA Replication Protein Localization To Organelle Negative Regulation Of DNA Biosynthetic Process Response To Temperature Stimulus Protein Localization To Chromosome Negative Regulation Of Cellular Metabolic Process Cellular Protein Localization Regulation Of Catalytic Activity Cellular Localization Cellular Response To Stress Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Cellular Response To Heat Positive Regulation Of DNA Replication Regulation Of Organelle Organization Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation
Tagcloud ?		1p 1p34 ataxia atm avian cip1 coded dnmt1 doxo doxorubicin heterozygosity histology intriguingly loh mycn myelocytomatosis nb nbs neuroblastoma originates paediatric reagent situations stabilisation sympathetic telangiectasia tumourigenesis unfavourable waf1	biosynthetic cd47 cycs dataset dj e2f6 eif2s1 eif2s2 encyclopedia extra fmr1 fxr2 gpr37 logical mapt nrf1 paelr park2 park6 park7 parkin pen2 perturbation pink1 psenen retrieved seq stringent unrecognized
Tagcloud (Difference) ?		1p 1p34 ataxia atm avian cip1 coded dnmt1 doxo doxorubicin heterozygosity histology intriguingly loh mycn myelocytomatosis nb nbs neuroblastoma originates paediatric reagent situations stabilisation sympathetic telangiectasia tumourigenesis unfavourable waf1	biosynthetic cd47 cycs dataset dj e2f6 eif2s1 eif2s2 encyclopedia extra fmr1 fxr2 gpr37 logical mapt nrf1 paelr park2 park6 park7 parkin pen2 perturbation pink1 psenen retrieved seq stringent unrecognized
Tagcloud (Intersection) ?