ZC4H2 and PLEKHN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZC4H2	PLEKHN1
Description		zinc finger C4H2-type containing	pleckstrin homology domain containing N1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Membrane Protein-containing Complex Neuronal Cell Body Synapse Postsynaptic Membrane	Mitochondrion Cytosol Cytoskeleton Plasma Membrane Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Phosphatidylserine Binding Protein Binding Phosphatidic Acid Binding Cardiolipin Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Noradrenergic Neuron Development Protein Monoubiquitination Nervous System Development Neuromuscular Junction Development Spinal Cord Motor Neuron Differentiation Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Transcription Regulatory Region DNA Binding	Response To Hypoxia Positive Regulation Of Apoptotic Process 3'-UTR-mediated MRNA Destabilization
Pathways
Drugs
Diseases
GWAS		Male-pattern baldness ( 28196072)	Height ( 31562340) Parkinson's disease ( 26227905)
Interacting Genes		22 interacting genes: ATP4B CMIP DGCR6 FAM161B GCC1 GEM HOXB5 KXD1 MECOM PLEKHN1 PRPH RNF151 SORBS3 TRIM14 ZNF223 ZNF250 ZNF408 ZNF490 ZNF524 ZNF669 ZNF688 ZNF76	42 interacting genes: ABI2 AKAP8L ARID5A ATXN1 CBY2 CYSRT1 FHL5 HOXA1 KRT31 KRT36 KRT83 KRTAP1-3 KRTAP19-6 KRTAP6-2 LPXN LZTS2 MTUS2 NBPF19 NFKBID NOTCH2NLA PDLIM7 PIH1D1 PPM1J PPP1R16B PRICKLE4 PRKAA2 REL RFX6 SAXO4 SORBS3 SSC4D TAX1BP1 TCF4 TP53BP2 TRAF1 TRIM27 TRIP6 USP54 WWOX ZC4H2 ZNF438 ZRANB1
Entrez ID		55906	84069
HPRD ID		06584	13190
Ensembl ID		ENSG00000126970	ENSG00000187583
Uniprot IDs		Q9NQZ6	Q494U1
PDB IDs
Enriched GO Terms of Interacting Partners?		Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Nucleus	Intermediate Filament Structural Constituent Of Skin Epidermis Keratin Filament
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