ZC4H2 and KXD1

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		ZC4H2	KXD1
Description		zinc finger C4H2-type containing	KxDL motif containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Membrane Protein-containing Complex Neuronal Cell Body Synapse Postsynaptic Membrane	Lysosome Lysosomal Membrane Membrane BLOC-1 Complex Cytoplasmic Side Of Lysosomal Membrane BORC Complex
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Noradrenergic Neuron Development Protein Monoubiquitination Nervous System Development Neuromuscular Junction Development Spinal Cord Motor Neuron Differentiation Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Transcription Regulatory Region DNA Binding	Vesicle-mediated Transport Lysosome Localization Regulation Of Endosome Size Regulation Of Lysosome Size Organelle Transport Along Microtubule
Pathways
Drugs
Diseases
GWAS		Male-pattern baldness ( 28196072)
Interacting Genes		22 interacting genes: ATP4B CMIP DGCR6 FAM161B GCC1 GEM HOXB5 KXD1 MECOM PLEKHN1 PRPH RNF151 SORBS3 TRIM14 ZNF223 ZNF250 ZNF408 ZNF490 ZNF524 ZNF669 ZNF688 ZNF76	42 interacting genes: APPL1 ARHGDIG C4orf46 CCDC185 CCDC33 CEP170P1 CEP19 CEP63 DYRK2 ELOA ELOA2 EWSR1 EXOC7 FXR2 GABARAPL1 HAUS1 IFT20 ING5 ITSN2 KRT81 LMO3 LNX1 LRRC45 MAB21L3 MAP1LC3A MAP1LC3B MCRS1 MOB1A MYH7 NIF3L1 NUDT18 RABGEF1 RNF183 RPL9 STX11 TCEA2 TPM1 TPM3 UTP6 ZBTB25 ZC4H2 ZNF417
Entrez ID		55906	79036
HPRD ID		06584	14526
Ensembl ID		ENSG00000126970	ENSG00000105700
Uniprot IDs		Q9NQZ6	Q9BQD3
PDB IDs
Enriched GO Terms of Interacting Partners?		Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Nucleus	Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Elongin Complex Muscle Thin Filament Tropomyosin Ciliary Basal Body Centrosome Transcription Elongation By RNA Polymerase II Cytoskeleton Protein Binding DNA-templated Transcription Elongation Autophagosome Maturation Autophagosome Membrane Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Mitophagy Muscle Filament Sliding Spindle Pole
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