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DCAF6 and SUPT5H
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
DCAF6
SUPT5H
Gene Name
DDB1 and CUL4 associated factor 6
suppressor of Ty 5 homolog (S. cerevisiae)
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Focal Adhesion
Cul4-RING E3 Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
DSIF Complex
Molecular Function
Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Chromatin Binding
Protein Binding
Enzyme Binding
Poly(A) RNA Binding
Protein Heterodimerization Activity
Biological Process
Protein Ubiquitination
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Remodeling
DNA-templated Transcription, Elongation
Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Cell Cycle
Response To Organic Substance
Gene Expression
Viral Process
Positive Regulation Of Macroautophagy
Negative Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of DNA-templated Transcription, Elongation
Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Viral Transcription
Pathways
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription
Abortive elongation of HIV-1 transcript in the absence of Tat
mRNA Capping
HIV Infection
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
Late Phase of HIV Life Cycle
Pausing and recovery of Tat-mediated HIV elongation
Formation of RNA Pol II elongation complex
HIV elongation arrest and recovery
HIV Life Cycle
RNA Pol II CTD phosphorylation and interaction with CE
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
HIV Transcription Elongation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Schizophrenia (
22037555
)
Protein-Protein Interactions
9 interactors:
ACVR1
AR
BMPR1B
NR3C1
SMAD2
SUPT5H
TGFBR1
TRIM55
TRIM63
37 interactors:
C9orf78
CCNH
CCNT1
CCNT2
CDK7
CDK9
CSNK2A1
DBN1
DCAF6
GTF3C1
H2AFX
HTATSF1
IK
IKBKG
LMAN2
MAML3
MNAT1
PCBD1
PHYHIP
PIN1
PNO1
POLR2A
PPIA
PPP2R2D
PRMT1
PRMT5
SAP30BP
SIK1
SNX4
SSBP3
SUPT4H1
TERF1
XRCC5
ZBTB3
ZFYVE9
ZNF496
ZNF512B
Entrez ID
55827
6829
HPRD ID
17156
03655
Ensembl ID
ENSG00000143164
ENSG00000196235
Uniprot IDs
Q58WW2
O00267
PDB IDs
3I7O
2DO3
2E6Z
2E70
3H7H
4L1U
Enriched GO Terms of Interacting Partners
?
Activin Receptor Signaling Pathway
Cellular Response To Organic Cyclic Compound
Response To Lipid
Response To Organic Cyclic Compound
Cellular Response To Steroid Hormone Stimulus
Regulation Of Extrinsic Apoptotic Signaling Pathway
Cellular Response To Glucocorticoid Stimulus
Cellular Response To Corticosteroid Stimulus
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Response To Organic Substance
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Urogenital System Development
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Pathway-restricted SMAD Protein Phosphorylation
Cellular Response To Lipid
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Organ Morphogenesis
Regulation Of Transcription From RNA Polymerase II Promoter
Transforming Growth Factor Beta Receptor Signaling Pathway
Cellular Response To Organic Substance
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pharyngeal System Development
Response To Steroid Hormone
Pattern Specification Process
Response To Glucocorticoid
Negative Regulation Of Signal Transduction
Regulation Of Gene Expression
Response To Corticosteroid
Response To Cholesterol
Transcription Initiation From RNA Polymerase II Promoter
Regulation Of Activin Receptor Signaling Pathway
Negative Regulation Of Signaling
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Cellular Response To Hormone Stimulus
Signal Transduction
Mesenchyme Development
Reproductive Process
DNA-templated Transcription, Initiation
Response To Stimulus
Signaling
Cell Communication
Regulation Of Apoptotic Process
Stem Cell Development
Developmental Process Involved In Reproduction
Negative Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Transcription Elongation From RNA Polymerase II Promoter
Positive Regulation Of Viral Process
Transcription, DNA-templated
RNA Biosynthetic Process
DNA-templated Transcription, Elongation
Positive Regulation Of Viral Transcription
Viral Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Viral Transcription
Macromolecule Biosynthetic Process
Regulation Of Viral Process
Regulation Of Nitrogen Compound Metabolic Process
RNA Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Cellular Nitrogen Compound Metabolic Process
DNA-templated Transcription, Initiation
Biosynthetic Process
Regulation Of Gene Expression
Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Regulation Of Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Regulation Of Cell Cycle
Regulation Of Cellular Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
7-methylguanosine MRNA Capping
7-methylguanosine RNA Capping
Transcription From RNA Polymerase II Promoter
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Transcription-coupled Nucleotide-excision Repair
Positive Regulation Of Metabolic Process
Cell Cycle
Cellular Metabolic Process
Nucleotide-excision Repair, DNA Damage Removal
Negative Regulation Of Gene Expression, Epigenetic
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Tagcloud
?
19q13
aa
acidic
argues
consensus
differ
end
family
homologue
lacks
like
map
maps
member
near
q
repeat
respond
ryanodine
seven
signals
similarity
spt5
spt6
terminus
unlike
w
yeast
Tagcloud (Difference)
?
19q13
aa
acidic
argues
consensus
differ
end
family
homologue
lacks
like
map
maps
member
near
q
repeat
respond
ryanodine
seven
signals
similarity
spt5
spt6
terminus
unlike
w
yeast
Tagcloud (Intersection)
?