DCAF6

Gene Name		DDB1 and CUL4 associated factor 6
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Focal Adhesion Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Protein Ubiquitination Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Schizophrenia ( 22037555)
Protein-protein Interactions		9 interactors: ACVR1 AR BMPR1B NR3C1 SMAD2 SUPT5H TGFBR1 TRIM55 TRIM63
Entrez ID		55827
HPRD ID		17156
Ensembl ID		ENSG00000143164
Uniprot IDs		Q58WW2
PDB IDs		3I7O
Enriched GO Terms of Interacting Partners?		Activin Receptor Signaling Pathway Cellular Response To Organic Cyclic Compound Response To Lipid Response To Organic Cyclic Compound Cellular Response To Steroid Hormone Stimulus Regulation Of Extrinsic Apoptotic Signaling Pathway Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Transcription, DNA-templated Response To Organic Substance Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Urogenital System Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Pathway-restricted SMAD Protein Phosphorylation Cellular Response To Lipid Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Organ Morphogenesis Regulation Of Transcription From RNA Polymerase II Promoter Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Transcription From RNA Polymerase II Promoter Pharyngeal System Development Response To Steroid Hormone Pattern Specification Process Response To Glucocorticoid Negative Regulation Of Signal Transduction Regulation Of Gene Expression Response To Corticosteroid Response To Cholesterol Transcription Initiation From RNA Polymerase II Promoter Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of Signaling Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Cellular Response To Hormone Stimulus Signal Transduction Mesenchyme Development Reproductive Process DNA-templated Transcription, Initiation Response To Stimulus Signaling Cell Communication Regulation Of Apoptotic Process Stem Cell Development Developmental Process Involved In Reproduction Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Cellular Metabolic Process
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