ZNF446 and PGBD1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZNF446	PGBD1
Gene Name		zinc finger protein 446	piggyBac transposable element derived 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus	Nucleus Membrane
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Metal Ion Binding	Sequence-specific DNA Binding Transcription Factor Activity Scavenger Receptor Activity
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter	Regulation Of Transcription, DNA-templated Receptor-mediated Endocytosis
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		25 interactors: ACTN2 DGCR6 DGCR6L FHL5 KRT40 KRTAP10-3 LZTS2 NOTCH2NL PGBD1 PIN1 SUFU TRIM27 ZKSCAN7 ZNF165 ZNF232 ZNF24 ZNF263 ZNF396 ZNF397 ZNF496 ZSCAN16 ZSCAN21 ZSCAN22 ZSCAN32 ZSCAN9	7 interactors: MEOX2 NR4A1 SCAND1 TRAF2 ZNF24 ZNF446 ZSCAN22
Entrez ID		55663	84547
HPRD ID		07934	11426
Ensembl ID		ENSG00000083838	ENSG00000137338
Uniprot IDs		Q9NWS9	Q96JS3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression RNA Metabolic Process Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Ion Transport Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Localization Negative Regulation Of Transport Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Negative Regulation Of Calcium Ion Import Microspike Assembly Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Negative Regulation Of Protein Localization To Cell Surface Interferon-gamma Secretion Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Spindle Midzone Assembly Negative Regulation Of Potassium Ion Transmembrane Transporter Activity	Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Somite Specification Negative Regulation Of Glial Cell Apoptotic Process Cell Death Death Cellular Metabolic Process Muscle Organ Development Positive Regulation Of Protein Homodimerization Activity Cellular Response To Nitric Oxide Striated Muscle Tissue Development Regulation Of Immunoglobulin Secretion Angiogenesis Muscle Tissue Development Response To Nitric Oxide Endothelial Cell Chemotaxis Regulation Of Endopeptidase Activity Segment Specification Protein Homotrimerization Positive Regulation Of T Cell Cytokine Production Regulation Of Protein Homodimerization Activity Regulation Of Peptidase Activity Cellular Response To Reactive Nitrogen Species Cell Migration Involved In Sprouting Angiogenesis Blood Vessel Morphogenesis Immune Response-regulating Signaling Pathway Regulation Of T Cell Cytokine Production
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