ZNF446 and ZNF397

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid, two hybrid)

		ZNF446	ZNF397
Gene Name		zinc finger protein 446	zinc finger protein 397
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus	Nucleus Cytoplasm
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Metal Ion Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		25 interactors: ACTN2 DGCR6 DGCR6L FHL5 KRT40 KRTAP10-3 LZTS2 NOTCH2NL PGBD1 PIN1 SUFU TRIM27 ZKSCAN7 ZNF165 ZNF232 ZNF24 ZNF263 ZNF396 ZNF397 ZNF496 ZSCAN16 ZSCAN21 ZSCAN22 ZSCAN32 ZSCAN9	6 interactors: LMO4 PRKAA2 SCAND1 ZNF396 ZNF410 ZNF446
Entrez ID		55663	84307
HPRD ID		07934	18335
Ensembl ID		ENSG00000083838	ENSG00000186812
Uniprot IDs		Q9NWS9	Q8NF99
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression RNA Metabolic Process Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Ion Transport Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Localization Negative Regulation Of Transport Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Negative Regulation Of Calcium Ion Import Microspike Assembly Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Negative Regulation Of Protein Localization To Cell Surface Interferon-gamma Secretion Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Spindle Midzone Assembly Negative Regulation Of Potassium Ion Transmembrane Transporter Activity	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Carnitine Shuttle Carnitine Transmembrane Transport Regulation Of Energy Homeostasis Carnitine Transport Positive Regulation Of Glycolytic Process Fatty Acid Homeostasis Spinal Cord Association Neuron Differentiation Quaternary Ammonium Group Transport Regulation Of Cell Fate Specification Ventral Spinal Cord Interneuron Differentiation Histone-serine Phosphorylation Dorsal Spinal Cord Development Cellular Metabolic Process Cellular Response To Glucose Starvation Regulation Of Glycolytic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of TOR Signaling Regulation Of Fatty Acid Biosynthetic Process Regulation Of Cell Fate Commitment Cholesterol Biosynthetic Process Positive Regulation Of Autophagy Long-chain Fatty Acid Transport Histone Phosphorylation Ammonium Transmembrane Transport Sterol Biosynthetic Process Anion Homeostasis Spinal Cord Motor Neuron Differentiation Ventricular Septum Development Ventral Spinal Cord Development Thymus Development
Tagcloud ?			18q11 alopecia apmr apmr1 apmr2 autosomes build covers d18s1102 d18s811 d18s866 dsc1 dsc3 dsg1 dsg3 dsg4 excluding flanked linkage lod multipoint polymorphic q12 retardation rutgers theta znf24 znf271
Tagcloud (Difference) ?			18q11 alopecia apmr apmr1 apmr2 autosomes build covers d18s1102 d18s811 d18s866 dsc1 dsc3 dsg1 dsg3 dsg4 excluding flanked linkage lod multipoint polymorphic q12 retardation rutgers theta znf24 znf271
Tagcloud (Intersection) ?