PLXNA3 and MAPK8IP2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		PLXNA3	MAPK8IP2
Gene Name		plexin A3	mitogen-activated protein kinase 8 interacting protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Semaphorin Receptor Complex Intracellular Plasma Membrane Membrane Integral Component Of Membrane	Cytoplasm Neuronal Cell Body Protein Complex Neuronal Postsynaptic Density
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Semaphorin Receptor Activity	Beta-amyloid Binding MAP-kinase Scaffold Activity Structural Molecule Activity Protein Binding Kinesin Binding Protein Kinase Binding Protein Kinase Activator Activity Protein Complex Binding
	Biological Process	Multicellular Organismal Development Axon Guidance Facial Nerve Structural Organization Trigeminal Nerve Structural Organization Hippocampus Development Branchiomotor Neuron Axon Guidance Pyramidal Neuron Development Negative Regulation Of Axon Extension Involved In Axon Guidance Negative Chemotaxis Positive Regulation Of Cytoskeleton Organization Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance	MAPK Cascade Behavioral Fear Response Signal Complex Assembly JNK Cascade Mating Behavior Regulation Of Receptor Activity Positive Regulation Of Stress-activated MAPK Cascade Social Behavior Positive Regulation Of Protein Kinase Activity Regulation Of JNK Cascade Nonassociative Learning Dendrite Morphogenesis Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity
Pathways		Axon guidance Semaphorin interactions Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CSNK2B MAPK8IP2 PPP2CB SMN1 TK1	52 interactors: ADRB2 AFG3L2 APP ASRGL1 BBS10 C14orf1 CFL1 CHN1 CRMP1 DUSP16 EGFR ERBB2 EZH2 FGF12 FSCN1 GBP2 ITSN1 KIFC2 KLC1 LRP1 LRP2 LRP8 MAGED4B MAP2K3 MAP2K7 MAP3K10 MAP3K11 MAP3K12 MAPK10 MAPK8 MAPK8IP1 MAPK8IP3 MAPK9 MASP1 NDUFS6 PLXNA3 PRSS23 RAI1 RBX1 RPS6KB2 SMARCB1 SMS SYNE2 TIAM1 TP53BP2 UNC119 VCP VPS33B VRK2 YY1AP1 ZNF593 ZNF784
Entrez ID		55558	23542
HPRD ID		02062	09674
Ensembl ID		ENSG00000130827	ENSG00000008735
Uniprot IDs		P51805	Q13387
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Macromolecular Complex Assembly Cellular Component Assembly Fetal Process Involved In Parturition Skeletal Muscle Cell Proliferation Response To Toxic Substance Protein Complex Assembly Nonassociative Learning Phosphate-containing Compound Metabolic Process Response To Cortisol Thymidine Metabolic Process Positive Regulation Of Activin Receptor Signaling Pathway Deoxyribonucleoside Monophosphate Biosynthetic Process Adiponectin-activated Signaling Pathway Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Cellular Protein Complex Assembly Endothelial Tube Morphogenesis Signal Complex Assembly Response To Inorganic Substance Parturition Negative Regulation Of Blood Vessel Endothelial Cell Migration System Development Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Phosphorylation Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Regulation Of Activin Receptor Signaling Pathway Response To Copper Ion Cell Morphogenesis Involved In Neuron Differentiation Multicellular Organismal Development Neuron Projection Morphogenesis Mating Behavior Negative Regulation Of Endothelial Cell Migration Anatomical Structure Development Nervous System Development Behavioral Fear Response Pyrimidine Nucleobase Metabolic Process Tube Development Fear Response Cell Morphogenesis Involved In Differentiation Social Behavior Positive Regulation Of Protein Phosphorylation Spliceosomal SnRNP Assembly Regulation Of Protein Kinase Activity Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Epithelial Cell Migration Response To Organic Substance Regulation Of Kinase Activity Pyrimidine Nucleoside Biosynthetic Process Neuron Projection Development	Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade JNK Cascade Signal Transduction By Phosphorylation MAPK Cascade Regulation Of Protein Kinase Activity Regulation Of MAPK Cascade Regulation Of Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Catalytic Activity Positive Regulation Of Kinase Activity JUN Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Transferase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Positive Regulation Of MAP Kinase Activity Response To Stress Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of MAPK Cascade Regulation Of Signal Transduction Response To Light Stimulus Response To External Stimulus Response To Radiation Regulation Of Signaling Intracellular Signal Transduction Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Axon Guidance Regulation Of Intracellular Signal Transduction Signal Transduction Axonogenesis Phosphorylation Cell Part Morphogenesis Axon Development Response To Stimulus Cell Morphogenesis Involved In Neuron Differentiation Response To Abiotic Stimulus Protein Phosphorylation Cellular Response To Stress Signaling
Tagcloud ?		analyse code crat ctsd ejaculated ejaculates elongating fertile fertilisation flna g6pd gapdh h3k9ac infertile intergenic mcf2l protamines semen semiquantitative sh3glb2 sox2 sperm spermatids spermatocytes spermatogenesis spermatogonia spermatozoa stk11ip testicular
Tagcloud (Difference) ?		analyse code crat ctsd ejaculated ejaculates elongating fertile fertilisation flna g6pd gapdh h3k9ac infertile intergenic mcf2l protamines semen semiquantitative sh3glb2 sox2 sperm spermatids spermatocytes spermatogenesis spermatogonia spermatozoa stk11ip testicular
Tagcloud (Intersection) ?