PIDD1 and MAFG

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PIDD1	MAFG
Gene Name		p53-induced death domain protein 1	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus	Nucleoplasm
	Molecular Function	Death Receptor Binding Protein Binding	Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To DNA Damage Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	In Utero Embryonic Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Blood Coagulation Adult Behavior Regulation Of Cellular PH Regulation Of Cell Proliferation Regulation Of Epidermal Cell Differentiation
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: AFP CASP2 CCDC85B CRADD EFEMP2 FADD KEAP1 MADD MAFG MDFI SOX8 TEAD3	26 interactors: ATF3 BACH1 BACH2 BATF3 CHD3 CREBBP CYP2E1 DDIT3 GTF2A1L HIF1A HOXD12 MAF MAFF MED31 NFE2 NFE2L1 NFE2L2 NFE2L3 NFIL3 PAX6 PIDD1 PPP1CA PRRX1 RBM48 SNRPN VIM
Entrez ID		55367	4097
HPRD ID		11284	03605
Ensembl ID		ENSG00000177595	ENSG00000197063
Uniprot IDs		Q9HB75	O15525
PDB IDs		2OF5
Enriched GO Terms of Interacting Partners?		Cellular Response To Mechanical Stimulus Extrinsic Apoptotic Signaling Pathway Regulation Of Cell Differentiation Response To Stimulus Reproductive Structure Development Positive Regulation Of Cellular Metabolic Process Reproductive System Development In Utero Embryonic Development Cellular Response To Stimulus Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cellular Protein Metabolic Process Signal Transduction Regulation Of Cysteine-type Endopeptidase Activity Response To Mechanical Stimulus Gonad Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Epidermal Cell Differentiation Development Of Primary Sexual Characteristics Protein Processing Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Signaling Regulation Of Proteolysis Regulation Of Cellular Process Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Reproductive Process Cell Communication Regulation Of Metabolic Process Developmental Process Involved In Reproduction Regulation Of Protein Metabolic Process Neural Retina Development DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Sex Differentiation Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Proteolysis Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Chordate Embryonic Development Regulation Of Apoptotic Process Embryo Development Ending In Birth Or Egg Hatching Regulation Of Epidermis Development Positive Regulation Of Metabolic Process Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Mitotic G1 DNA Damage Checkpoint Regulation Of Cell Death Apoptotic Signaling Pathway Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint	Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Cellular Process Multicellular Organismal Development Anatomical Structure Development Positive Regulation Of Cellular Metabolic Process Limb Development Positive Regulation Of Stem Cell Proliferation Response To Stress Developmental Process MRNA Transcription From RNA Polymerase II Promoter System Development Organ Development
Tagcloud ?			albeit arrested asymmetric constitute dimerizes dissect e2 erythroid heterodimeric lineages livers maff mafk megakaryocyte megakaryocytes megakaryocytic mpl nucleotides outside p18 p45 polypeptides predominate profound rarity readily recognizes thrombocytopenia
Tagcloud (Difference) ?			albeit arrested asymmetric constitute dimerizes dissect e2 erythroid heterodimeric lineages livers maff mafk megakaryocyte megakaryocytes megakaryocytic mpl nucleotides outside p18 p45 polypeptides predominate profound rarity readily recognizes thrombocytopenia
Tagcloud (Intersection) ?