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PIDD1 and TEAD3
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
PIDD1
TEAD3
Gene Name
p53-induced death domain protein 1
TEA domain family member 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Golgi Apparatus
Nucleoplasm
Transcription Factor Complex
Molecular Function
Death Receptor Binding
Protein Binding
RNA Polymerase II Transcription Factor Binding
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Biological Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cellular Response To DNA Damage Stimulus
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Female Pregnancy
Gene Expression
Hippo Signaling
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Stem Cell Maintenance
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Generic Transcription Pathway
Metabolism of lipids and lipoproteins
YAP1- and WWTR1 (TAZ)-stimulated gene expression
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions
12 interactors:
AFP
CASP2
CCDC85B
CRADD
EFEMP2
FADD
KEAP1
MADD
MAFG
MDFI
SOX8
TEAD3
13 interactors:
AP4S1
CTBP2
E2F1
E2F3
KIFC2
MYH7
PHB2
PIDD1
SUMO2
VGLL1
VGLL2
WWTR1
YAP1
Entrez ID
55367
7005
HPRD ID
11284
04411
Ensembl ID
ENSG00000177595
ENSG00000007866
Uniprot IDs
Q9HB75
Q99594
PDB IDs
2OF5
Enriched GO Terms of Interacting Partners
?
Cellular Response To Mechanical Stimulus
Extrinsic Apoptotic Signaling Pathway
Regulation Of Cell Differentiation
Response To Stimulus
Reproductive Structure Development
Positive Regulation Of Cellular Metabolic Process
Reproductive System Development
In Utero Embryonic Development
Cellular Response To Stimulus
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cellular Protein Metabolic Process
Signal Transduction
Regulation Of Cysteine-type Endopeptidase Activity
Response To Mechanical Stimulus
Gonad Development
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Epidermal Cell Differentiation
Development Of Primary Sexual Characteristics
Protein Processing
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Signal Transduction
Signaling
Regulation Of Proteolysis
Regulation Of Cellular Process
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Reproductive Process
Cell Communication
Regulation Of Metabolic Process
Developmental Process Involved In Reproduction
Regulation Of Protein Metabolic Process
Neural Retina Development
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Sex Differentiation
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Proteolysis
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Chordate Embryonic Development
Regulation Of Apoptotic Process
Embryo Development Ending In Birth Or Egg Hatching
Regulation Of Epidermis Development
Positive Regulation Of Metabolic Process
Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation
Mitotic G1 DNA Damage Checkpoint
Regulation Of Cell Death
Apoptotic Signaling Pathway
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Transcription, DNA-templated
Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation
RNA Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Regulation Of Nephron Tubule Epithelial Cell Differentiation
Regulation Of Epithelial Cell Differentiation Involved In Kidney Development
Regulation Of Cell Proliferation
Regulation Of Transcription, DNA-templated
Positive Regulation Of Macromolecule Biosynthetic Process
RNA Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Cellular Biosynthetic Process
Hippo Signaling
Positive Regulation Of Metabolic Process
Gene Expression
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
DNA-templated Transcription, Initiation
Positive Regulation Of Stem Cell Differentiation
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Cell Proliferation
Nucleobase-containing Compound Metabolic Process
Regulation Of Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Tissue Development
Organ Morphogenesis
Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Cellular Nitrogen Compound Metabolic Process
Signal Transduction By P53 Class Mediator
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Signal Transduction
Lens Fiber Cell Apoptotic Process
Negative Regulation Of Transcription, DNA-templated
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Epithelial Cell Differentiation
Notch Signaling Pathway
Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
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