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PIDD1
Gene Name
p53-induced death domain protein 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Golgi Apparatus
Molecular Function
Death Receptor Binding
Protein Binding
Biological Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cellular Response To DNA Damage Stimulus
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
12 interactors:
AFP
CASP2
CCDC85B
CRADD
EFEMP2
FADD
KEAP1
MADD
MAFG
MDFI
SOX8
TEAD3
Entrez ID
55367
HPRD ID
11284
Ensembl ID
ENSG00000177595
Uniprot IDs
Q9HB75
PDB IDs
2OF5
Enriched GO Terms of Interacting Partners
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Cellular Response To Mechanical Stimulus
Extrinsic Apoptotic Signaling Pathway
Regulation Of Cell Differentiation
Response To Stimulus
Reproductive Structure Development
Positive Regulation Of Cellular Metabolic Process
Reproductive System Development
In Utero Embryonic Development
Cellular Response To Stimulus
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cellular Protein Metabolic Process
Signal Transduction
Regulation Of Cysteine-type Endopeptidase Activity
Response To Mechanical Stimulus
Gonad Development
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Epidermal Cell Differentiation
Development Of Primary Sexual Characteristics
Protein Processing
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Signal Transduction
Signaling
Regulation Of Proteolysis
Regulation Of Cellular Process
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Reproductive Process
Cell Communication
Regulation Of Metabolic Process
Developmental Process Involved In Reproduction
Regulation Of Protein Metabolic Process
Neural Retina Development
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Sex Differentiation
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Proteolysis
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Chordate Embryonic Development
Regulation Of Apoptotic Process
Embryo Development Ending In Birth Or Egg Hatching
Regulation Of Epidermis Development
Positive Regulation Of Metabolic Process
Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation
Mitotic G1 DNA Damage Checkpoint
Regulation Of Cell Death
Apoptotic Signaling Pathway
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
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