RNF123 and UBAC1

Number of citations of the paper that reports this interaction (PMID 15531880)
100

Data Source:
HPRD (in vivo, in vitro)

		RNF123	UBAC1
Gene Name		ring finger protein 123	UBA domain containing 1
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Gene Ontology Annotations	Cellular Component	Cytoplasm	Cytoplasm Golgi Apparatus Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Zinc Ion Binding Ligase Activity	Protein Binding
	Biological Process	Protein Ubiquitination	Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CDKN1B SMAD2 SMAD9 UBAC1 UBE2W	14 interactors: AIRE APP CDKN1B CPSF6 CSNK2A1 DAZAP2 HTT LAPTM5 NEDD4L RNF11 RNF123 TRIM2 TRIM39 ZDHHC17
Entrez ID		63891	10422
HPRD ID		11499	12170
Ensembl ID		ENSG00000164068	ENSG00000130560
Uniprot IDs		C9JS59 Q5XPI4	Q9BSL1
PDB IDs		2MA6	2DAI
Enriched GO Terms of Interacting Partners?		Cellular Response To Organic Cyclic Compound Cellular Response To Growth Factor Stimulus Response To Growth Factor Cellular Response To Organic Substance Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Response To Glucose Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Kidney Epithelium Development Response To Organic Cyclic Compound Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Response To Carbohydrate Response To Organic Substance Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Zygotic Specification Of Dorsal/ventral Axis Response To Transforming Growth Factor Beta Protein Metabolic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Mesoderm Development Primary MiRNA Processing Autophagic Cell Death Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Response To Hypoxia Positive Regulation Of Activin Receptor Signaling Pathway Mullerian Duct Regression Cellular Protein Modification Process Kidney Development Renal System Development SMAD Protein Complex Assembly Urogenital System Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Paraxial Mesoderm Morphogenesis Positive Regulation Of Microtubule Polymerization Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Nodal Signaling Pathway Mitotic Cell Cycle Arrest Response To Misfolded Protein Cellular Response To Lithium Ion Anatomical Structure Regression Cellular Response To Antibiotic Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Intracellular Signal Transduction Production Of MiRNAs Involved In Gene Silencing By MiRNA Embryonic Foregut Morphogenesis	Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Protein Catabolic Process Cellular Protein Modification Process Apoptotic Process MRNA Polyadenylation Programmed Cell Death Positive Regulation Of Cation Channel Activity Cell Death Death RNA Polyadenylation Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Growth Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Proteolysis Axon Cargo Transport Mating Positive Regulation Of Transporter Activity Positive Regulation Of Cell Cycle Neuron Apoptotic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Visual Learning Protein Metabolic Process Regulation Of Protein Metabolic Process Neural Plate Formation Visual Behavior Neuron Death Cellular Protein Metabolic Process Response To Metal Ion Regulation Of Apoptotic Process Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Ion Transmembrane Transport Negative Regulation Of Cellular Protein Catabolic Process Regulation Of Cation Channel Activity Negative Regulation Of Proteolysis Metal Ion Transport MRNA 3'-end Processing Negative Regulation Of Protein Processing Regulation Of Cell Death Associative Learning Negative Regulation Of Protein Metabolic Process Regulation Of Endopeptidase Activity Synaptic Growth At Neuromuscular Junction Serotonin Uptake Positive Regulation Of Caveolin-mediated Endocytosis Lactate Biosynthetic Process From Pyruvate Regulation Of Protein Processing Regulation Of Cell Cycle
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