PPIG and PNMA2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PPIG	PNMA2
Description		peptidylprolyl isomerase G	PNMA family member 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Speck	Nucleus Nucleolus
	Molecular Function	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Isomerase Activity	Protein Binding
	Biological Process	Protein Folding RNA Splicing	Positive Regulation Of Apoptotic Process
Pathways		mRNA Splicing - Major Pathway SARS-CoV-1 activates/modulates innate immune responses
Drugs		Proline
Diseases
GWAS			Age at first sexual intercourse ( 34211149) Brain morphology (MOSTest) ( 32665545) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		26 interacting genes: BEND7 CACNA1A CEP70 CLK1 DAB1 DACH1 FHL3 KCTD6 LGALS3 PCBP1 PNMA2 PNN POLR2A PPCDC PRPF38A PRPF40A RNF10 SLU7 SMN1 SMN2 SP1 TFCP2 THAP1 TRIM54 YWHAG ZCCHC10	32 interacting genes: BYSL CBX8 CCDC33 CDC37 CNNM3 ENKD1 FAM161A GPATCH2L HAPLN2 INO80B LRR1 MISP MORF4L2 NTAQ1 PPIG PRPF31 PSMA1 RNF6 RNF8 RPL9 RSPH1 RTP5 SCNM1 SDCBP THAP7 TOP3B TTLL10 ZNF408 ZNF417 ZNF587 ZNF669 ZNF688
Entrez ID		9360	10687
HPRD ID		12083	04915
Ensembl ID		ENSG00000138398	ENSG00000240694
Uniprot IDs		Q13427	Q5U5Z3 Q9UL42
PDB IDs		2GW2 2WFI 2WFJ 5YZG	8UYO
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process RNA Splicing RNA Splicing, Via Transesterification Reactions RNA Metabolic Process MRNA Processing DNA-templated Transcription Termination Z Disc Nucleus Nucleic Acid Metabolic Process SMN Complex Gemini Of Cajal Bodies Spliceosomal Complex Nucleobase-containing Compound Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Biosynthetic Process Cytoplasmic Ribonucleoprotein Granule SMN-Sm Protein Complex RNA Binding Nuclear Speck Transcription Cis-regulatory Region Binding DNA Binding Nucleoplasm Protein Binding Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Positive Regulation Of Hydrogen Sulfide Biosynthetic Process Cellular Response To Wortmannin Second Spliceosomal Transesterification Activity Phosphopantothenoylcysteine Decarboxylase Activity Phosphopantothenoylcysteine Decarboxylase Complex	Nucleus
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