TMEM161A and OXTR

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		TMEM161A	OXTR
Description		transmembrane protein 161A	oxytocin receptor
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity Oxytocin Receptor Activity Vasopressin Receptor Activity
	Biological Process	Response To Retinoic Acid Cellular Response To Oxidative Stress Cellular Response To UV Positive Regulation Of DNA Repair Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Regulation Of Systemic Arterial Blood Pressure By Vasopressin System Process Muscle Contraction Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Female Pregnancy Lactation Cellular Response To Hormone Stimulus Positive Regulation Of Blood Pressure Positive Regulation Of Vasoconstriction Maternal Process Involved In Parturition Regulation Of Biological Quality Positive Regulation Of Cold-induced Thermogenesis
Pathways			Vasopressin-like receptors G alpha (q) signalling events
Drugs			Vasopressin Oxytocin Carbetocin Atosiban Relcovaptan
Diseases
GWAS			Caudate activity during reward ( 28927378) Chronotype ( 30696823) Depression and alcohol dependence ( 22064162) Liver fibrosis severity in HIV/hepatitis C co-infection ( 27339598) Morning person ( 30696823)
Interacting Genes		12 interacting genes: AGTR1 CCR2 CHRM5 F2RL1 GNRHR GPR35 GPR37 NR1H2 NR1H3 OXTR PTGER4 SLC22A2	18 interacting genes: ALAS1 ARRB2 ASH1L AVP CD81 CYFIP2 EMC10 FSCN1 GPRASP1 LCNL1 MVB12A OXT PSMA7 SIRT2 THOC5 TMEM161A TSPAN7 YIPF3
Entrez ID		54929	5021
HPRD ID		07905	01328
Ensembl ID		ENSG00000064545	ENSG00000180914
Uniprot IDs		K7EPA3 Q9NX61	B2R9L7 P30559
PDB IDs			6TPK 7QVM 7RYC
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Biological Quality Regulation Of Body Fluid Levels Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Cold-induced Thermogenesis Regulation Of Systemic Arterial Blood Pressure Negative Regulation Of Pinocytosis Signal Transduction Regulation Of Inflammatory Response Negative Regulation Of Transport Negative Regulation Of Type II Interferon-mediated Signaling Pathway Positive Regulation Of Defense Response Regulation Of Defense Response Negative Regulation Of Cholesterol Storage Vascular Process In Circulatory System Regulation Of System Process Regulation Of Secretion By Cell Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Immune System Process Negative Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Triglyceride Biosynthetic Process Regulation Of Type II Interferon-mediated Signaling Pathway Regulation Of Response To Type II Interferon Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Response To Cytokine Stimulus Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Phosphatidylcholine Acyl-chain Remodeling Regulation Of Secretion Circulatory System Process Regulation Of Lipid Metabolic Process Regulation Of Triglyceride Biosynthetic Process Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure Dopamine Transport Negative Regulation Of Lipid Storage Positive Regulation Of Triglyceride Metabolic Process Chemokine Receptor Activity Positive Regulation Of Fatty Acid Biosynthetic Process Regulation Of Lipid Transport Positive Regulation Of Lipid Metabolic Process Apoptotic Cell Clearance Positive Regulation Of Metabolic Process Negative Regulation Of Secretion By Cell Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Blood Vessel Diameter Maintenance Regulation Of Tube Size Plasma Membrane Positive Regulation Of Cholesterol Efflux Positive Regulation Of Small Molecule Metabolic Process	Neurohypophyseal Hormone Activity Maternal Aggressive Behavior Regulation Of Female Receptivity Female Mating Behavior Aggressive Behavior Maternal Behavior Grooming Behavior Parental Behavior Receptor Catabolic Process Mating Behavior Neuronal Dense Core Vesicle Positive Regulation Of Fatty Acid Biosynthetic Process Neuropeptide Hormone Activity Positive Regulation Of Blood Pressure Regulation Of Fatty Acid Biosynthetic Process Response To Electrical Stimulus Reproductive Behavior V1B Vasopressin Receptor Binding Positive Regulation Of Fatty Acid Metabolic Process Macrophage Fusion Positive Regulation Of Adaptive Immune Memory Response CD4-positive, Alpha-beta T Cell Costimulation Positive Regulation Of Hindgut Contraction Oxytocin Receptor Binding Receptor Metabolic Process Negative Regulation Of Oligodendrocyte Progenitor Proliferation Cellular Response To Caloric Restriction Tarsal Gland Development Uterine Gland Development
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?