NUTM2F and SH3GL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NUTM2F	SH3GL1
Description		NUT family member 2F	SH3 domain containing GRB2 like 1, endophilin A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Podosome Cytoplasm Endosome Cytosol Membrane Early Endosome Membrane Cell Projection Anchoring Junction Presynapse Glutamatergic Synapse
	Molecular Function		Protein Binding Lipid Binding Identical Protein Binding Cadherin Binding
	Biological Process		Endocytosis Signal Transduction Central Nervous System Development
Pathways			EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Body mass index ( 28892062) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954)	Appendicular lean mass ( 33097823) Hematocrit ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		20 interacting genes: AIRIM ANKS1A ATXN1L FADD GRB2 HGS LENG8 MORN4 NCK1 NCK2 NFYC OSTF1 PRPF18 RAD23A RBM47 SH3GL1 SH3RF1 VPS37C ZMYND10 ZNF148	35 interacting genes: ARHGAP1 ARHGAP8 AXIN1 B3GAT1 CCDC50 CMTM5 CREBBP DNM1 DNM1L DPPA4 DPYSL4 EEIG1 FBXO32 GPKOW ITCH ITSN2 MAL2 MTA1 NUTM2F PDCD6IP PML PRB3 PSMB1 PTPRO RHEX SCAMP5 SEPTIN8 SH2D4A SH3D19 SH3GL3 SOCS1 SPG21 SYNJ1 VPS37C YWHAZ
Entrez ID		54754	6455
HPRD ID		19318	03462
Ensembl ID		ENSG00000130950	ENSG00000141985
Uniprot IDs		A1L443	Q6FGM0 Q99961
PDB IDs
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Binding Vesicle Membrane Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Actin Filament Polymerization Ephrin Receptor Signaling Pathway Positive Regulation Of Translation In Response To Stress Signal Complex Assembly Regulation Of Translation In Response To Endoplasmic Reticulum Stress Regulation Of T Cell Proliferation Regulation Of Translational Initiation In Response To Stress Regulation Of T Cell Activation Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of PERK-mediated Unfolded Protein Response Signaling Adaptor Activity Positive Regulation Of Protein Polymerization Regulation Of PERK-mediated Unfolded Protein Response Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of T Cell Activation Positive Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Lymphocyte Activation Cytoskeletal Anchor Activity Positive Regulation Of T Cell Proliferation Regulation Of Translation In Response To Stress Regulation Of Leukocyte Proliferation Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Type I Interferon-mediated Signaling Pathway T Cell Activation Regulation Of Actin Filament Polymerization Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Cell-cell Adhesion Positive Regulation Of Lymphocyte Activation Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Cell Activation Signaling Receptor Complex Adaptor Activity Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Multivesicular Body Organization Multivesicular Body Assembly Lamellipodium Assembly Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Unfolded Protein Response Late Endosome To Vacuole Transport Positive Regulation Of Supramolecular Fiber Organization Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Cell Activation	Negative Regulation Of Endocytic Recycling Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cytoplasm Membrane Fission
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