GNL3L and LDOC1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GNL3L	LDOC1
Gene Name		guanine nucleotide binding protein-like 3 (nucleolar)-like	leucine zipper, down-regulated in cancer 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Membrane	Nucleus Nucleolus
	Molecular Function	GTPase Activity Protein Binding GTP Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	Metabolic Process Ribosome Biogenesis	Negative Regulation Of Cell Proliferation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ADRB2 ALAS1 LDOC1 LZTS2 ROPN1 TERF1	62 interactors: AATF ABLIM1 AEBP2 AES AP1M1 ATF4 ATP6V1G1 BARD1 C1orf109 CCDC33 CCDC85B CEBPE CTNNBL1 DPF2 DPPA4 FAM107A FAM193B FAM208B FAM50B FAM90A1 FOSL1 FXR2 GNL3L HAUS1 HDAC4 HGS IKZF5 INPP1 KRT15 KRT18 LATS1 LENG1 LNX1 MEAF6 MFAP1 MYC MZF1 NRIP1 NXF1 PEG10 PLEKHF2 POLL PRPF31 PSMA1 PSMF1 RAB29 SDCBP SETD5 SH2D4A SMARCD1 TBC1D7 TMSB4XP1 TNNT1 TTC23 UTP14A ZBTB16 ZBTB24 ZGPAT ZNF250 ZNF408 ZNF564 ZNF774
Entrez ID		54552	23641
HPRD ID		06514	02322
Ensembl ID			ENSG00000182195
Uniprot IDs		Q05DU1 Q9NVN8	O95751
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Telomeric Loop Formation Age-dependent Telomere Shortening Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Protein Complex Assembly Telomere Maintenance Via Telomere Shortening Negative Regulation Of Telomere Maintenance Via Telomerase Heat Generation Diet Induced Thermogenesis Mitotic Nuclear Division Replicative Cell Aging Protoporphyrinogen IX Biosynthetic Process Cellular Protein Complex Assembly Regulation Of Nuclear Cell Cycle DNA Replication Spindle Midzone Assembly Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Protoporphyrinogen IX Metabolic Process Microtubule Severing Positive Regulation Of Microtubule Polymerization Cell Division Negative Regulation Of Smooth Muscle Contraction Regulation Of Telomerase Activity Adrenergic Receptor Signaling Pathway Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Response To Dietary Excess Regulation Of Telomere Maintenance Negative Regulation Of Multicellular Organism Growth Cellular Component Assembly Negative Regulation Of Muscle Contraction RNA-dependent DNA Replication Negative Regulation Of Systemic Arterial Blood Pressure Negative Regulation Of DNA Biosynthetic Process Temperature Homeostasis Heme Biosynthetic Process Activation Of Adenylate Cyclase Activity Regulation Of Microtubule Polymerization Endosome To Lysosome Transport Telomere Maintenance Via Telomere Lengthening Cellular Macromolecular Complex Assembly Vasodilation Mitotic Spindle Assembly Checkpoint Bone Resorption Negative Regulation Of Cell Proliferation Positive Regulation Of Adenylate Cyclase Activity Spindle Assembly Checkpoint	Gene Expression Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Apoptotic Process Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Programmed Cell Death Cell Death Death Negative Regulation Of Gene Expression Regulation Of Cellular Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Apoptotic Process Biosynthetic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Gene Expression Regulation Of Cell Death Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Negative Regulation Of Wnt Signaling Pathway Melanosome Organization Pigment Granule Organization
Tagcloud ?		60s appreciable biogenesis carrying collapse delays depth description faceted gnl2 homology impairments lethality ns nucleostemin obscure rescue rescues ribosome rrna stabilization surprisingly ultimately unexpected unrelated vertebrate vertebrates zebrafish	abcc5 cabpr cbr3 clonogenic comprehensive differentially dock8 dsc2 esophageal extracted fabp5 global gpx2 hence know microarray ndn nme oligonucleotide radiation radioresistant radiosensitive radiosensitivities radiosensitivity radiotherapy rpa1 skp1a spot te
Tagcloud (Difference) ?		60s appreciable biogenesis carrying collapse delays depth description faceted gnl2 homology impairments lethality ns nucleostemin obscure rescue rescues ribosome rrna stabilization surprisingly ultimately unexpected unrelated vertebrate vertebrates zebrafish	abcc5 cabpr cbr3 clonogenic comprehensive differentially dock8 dsc2 esophageal extracted fabp5 global gpx2 hence know microarray ndn nme oligonucleotide radiation radioresistant radiosensitive radiosensitivities radiosensitivity radiotherapy rpa1 skp1a spot te
Tagcloud (Intersection) ?